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Page 1
Showing results for autoantibodies sex the vasculature.
Search for Autoantibodies vex the vasculature. instead (1 results)
Contribution of Sex and Autoantibodies to Microangiopathy Assessed by Nailfold Videocapillaroscopy in Systemic Sclerosis: A Systematic Review of the Literature.
van Leeuwen NM, Ciaffi J, Schoones JW, Huizinga TWJ, de Vries-Bouwstra JK. van Leeuwen NM, et al. Arthritis Care Res (Hoboken). 2021 May;73(5):722-731. doi: 10.1002/acr.24149. Epub 2021 Apr 3. Arthritis Care Res (Hoboken). 2021. PMID: 31962005 Free PMC article.
RESULTS: We included 11 studies that described the relationship between SSc-specific autoantibodies and microangiopathy and 6 studies that reported on the association between sex and microangiopathy. Contradictory results were found on the association between SSc-sp …
RESULTS: We included 11 studies that described the relationship between SSc-specific autoantibodies and microangiopathy and 6 studies …
Autoimmune Disease-Associated Hypertension.
Wolf VL, Ryan MJ. Wolf VL, et al. Curr Hypertens Rep. 2019 Feb 2;21(1):10. doi: 10.1007/s11906-019-0914-2. Curr Hypertens Rep. 2019. PMID: 30712132 Free PMC article. Review.
A complex interaction among genetic, environmental, hormonal, and metabolic factors contribute to autoimmune disease susceptibility while promoting chronic inflammation that can lead to alterations in blood pressure. Recent studies emphasize an important mechanistic role f …
A complex interaction among genetic, environmental, hormonal, and metabolic factors contribute to autoimmune disease susceptibility while pr …
Autoantibodies are present before the clinical diagnosis of systemic sclerosis.
Burbelo PD, Gordon SM, Waldman M, Edison JD, Little DJ, Stitt RS, Bailey WT, Hughes JB, Olson SW. Burbelo PD, et al. PLoS One. 2019 Mar 26;14(3):e0214202. doi: 10.1371/journal.pone.0214202. eCollection 2019. PLoS One. 2019. PMID: 30913258 Free PMC article. Clinical Trial.
Systemic sclerosis (SSc) is a heterogeneous autoimmune disorder associated with vascular dysfunction and fibrotic changes in the skin, vasculature and internal organs. Although serologic abnormalities are an important diagnostic tool for SSc, little is known about whether …
Systemic sclerosis (SSc) is a heterogeneous autoimmune disorder associated with vascular dysfunction and fibrotic changes in the skin, va …
Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice.
Garciafigueroa Y, Phillips BE, Engman C, Trucco M, Giannoukakis N. Garciafigueroa Y, et al. Front Endocrinol (Lausanne). 2021 Mar 10;12:565981. doi: 10.3389/fendo.2021.565981. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 33776903 Free PMC article.
We also detect components of neutrophil extracellular traps (NET) mainly in the exocrine tissue of the pancreas during this time as well as markers of vascular pathology as early as 2 weeks of age. Age- and sex-matched C57BL/6 mice do not exhibit these features inside the …
We also detect components of neutrophil extracellular traps (NET) mainly in the exocrine tissue of the pancreas during this time as well as …
The pathogenesis, diagnosis and treatment of Raynaud phenomenon.
Herrick AL. Herrick AL. Nat Rev Rheumatol. 2012 Aug;8(8):469-79. doi: 10.1038/nrrheum.2012.96. Epub 2012 Jul 10. Nat Rev Rheumatol. 2012. PMID: 22782008 Review.
Although the pathogenesis of Raynaud phenomenon is complex, abnormalities of the blood vessel wall, of neural control mechanisms and of intravascular (circulating) factors are known to interact and contribute. ...The main advances in diagnosis have been a clearer understan …
Although the pathogenesis of Raynaud phenomenon is complex, abnormalities of the blood vessel wall, of neural control mechanisms and …
Role of Selenium Intake for Risk and Development of Hyperthyroidism.
Wang Y, Zhao F, Rijntjes E, Wu L, Wu Q, Sui J, Liu Y, Zhang M, He M, Chen P, Hu S, Hou P, Schomburg L, Shi B. Wang Y, et al. J Clin Endocrinol Metab. 2019 Feb 1;104(2):568-580. doi: 10.1210/jc.2018-01713. J Clin Endocrinol Metab. 2019. PMID: 30265356
We investigated the effects of a different dietary Se supply (0.02, 0.18, 0.6, or 2.0 ppm Se) on disease development in a mouse model of Graves disease (GD). RESULTS: The cross-sectional study revealed a comparable prevalence of hyperthyroidism, irrespective of Se intake, …
We investigated the effects of a different dietary Se supply (0.02, 0.18, 0.6, or 2.0 ppm Se) on disease development in a mouse model …
Pericyte dysfunction and impaired vasomotion are hallmarks of islets during the pathogenesis of type 1 diabetes.
Mateus Gonçalves L, Fahd Qadir MM, Boulina M, Makhmutova M, Pereira E, Almaça J. Mateus Gonçalves L, et al. Cell Rep. 2023 Aug 29;42(8):112913. doi: 10.1016/j.celrep.2023.112913. Epub 2023 Aug 1. Cell Rep. 2023. PMID: 37531253 Free PMC article.
Here, we investigate islet pericyte density, phenotype, and function using living pancreas slices from donors without diabetes, donors with a single T1D-associated autoantibody (GADA+), and recent onset T1D cases. Our data show that islet pericyte and capillary responses t …
Here, we investigate islet pericyte density, phenotype, and function using living pancreas slices from donors without diabetes, donors with …
Autoantibodies against Endothelin 1 Type A Receptor Are Strong Predictors of Digital Ulcers in Systemic Sclerosis.
Avouac J, Riemekasten G, Meune C, Ruiz B, Kahan A, Allanore Y. Avouac J, et al. J Rheumatol. 2015 Oct;42(10):1801-7. doi: 10.3899/jrheum.150061. Epub 2015 Aug 1. J Rheumatol. 2015. PMID: 26233500
A first multivariate Cox analysis including functional autoantibodies and clinical predictors of new DU confirmed anti-ETAR autoantibodies as independent predictors of the occurrence of new ischemic DU (HR 3.15, 95% CI 1.22-8.13) together with a history of DU at bas …
A first multivariate Cox analysis including functional autoantibodies and clinical predictors of new DU confirmed anti-ETAR autoan …
Intracranial hemodynamic changes in primary Sjögren syndrome: a transcranial Doppler case-control study.
Morreale M, Francia A, Marchione P, Manuppella F, Giacomini P. Morreale M, et al. Neurol Sci. 2015 Sep;36(9):1589-95. doi: 10.1007/s10072-015-2204-3. Epub 2015 Apr 14. Neurol Sci. 2015. PMID: 25868598
The increase in systolic-diastolic ratio significantly correlates with neuropsychological impairment. Anti-SSA autoantibodies positively correlate with impaired systolic-diastolic ratio and with neuropsychiatric symptoms. The correlation between haemodynamic changes and an …
The increase in systolic-diastolic ratio significantly correlates with neuropsychological impairment. Anti-SSA autoantibodies positiv …
Haptoglobin 2-2 genotype is associated with increased risk of cardiovascular disease in patients with rheumatoid arthritis: a matched case-control study.
Xu C, Khin LW, Tam HZ, Goh LL, Koh ET, Dalan R, Leong KP. Xu C, et al. Front Med (Lausanne). 2024 Dec 17;11:1442858. doi: 10.3389/fmed.2024.1442858. eCollection 2024. Front Med (Lausanne). 2024. PMID: 39741512 Free PMC article.
The Haptoglobin (Hp) 2-2 genotype confers a lower anti-oxidant and higher inflammatory effect on the vasculature compared to the non-Hp 2-2 genotype. This study investigates the association of the Hp genotype with CVD in patients with RA. METHODS: Data from 69 RA patients …
The Haptoglobin (Hp) 2-2 genotype confers a lower anti-oxidant and higher inflammatory effect on the vasculature compared to the non- …
37 results