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1970 1
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1985 3
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1989 8
1990 2
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1992 4
1993 3
1994 2
1995 3
1996 2
1997 8
1998 5
1999 8
2000 3
2001 10
2002 14
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2004 17
2005 10
2006 8
2007 13
2008 13
2009 17
2010 10
2011 11
2012 17
2013 12
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623 results

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Page 1
Autoimmune chronic spontaneous urticaria.
Kolkhir P, Muñoz M, Asero R, Ferrer M, Kocatürk E, Metz M, Xiang YK, Maurer M. Kolkhir P, et al. J Allergy Clin Immunol. 2022 Jun;149(6):1819-1831. doi: 10.1016/j.jaci.2022.04.010. J Allergy Clin Immunol. 2022. PMID: 35667749 Review.
Chronic spontaneous urticaria (CSU) is a debilitating mast cell-driven disease characterized by recurrent wheals and/or angioedema. Substantial progress has been made in dissecting the 2 main autoimmune mechanisms that drive the pathogenesis of CSU. ...Further studi …
Chronic spontaneous urticaria (CSU) is a debilitating mast cell-driven disease characterized by recurrent wheals and/or angioedema. S …
Chronic Spontaneous Urticaria: A Review.
Kolkhir P, Bonnekoh H, Metz M, Maurer M. Kolkhir P, et al. JAMA. 2024 Nov 5;332(17):1464-1477. doi: 10.1001/jama.2024.15568. JAMA. 2024. PMID: 39325444 Review.
Diagnosis is based on clinical presentation, ie, spontaneously recurring wheals, angioedema, or both. Chronic spontaneous urticaria persists for more than 1 year in most patients (1 or repeated episodes) and may present with comorbidities including chronic inducible urtica …
Diagnosis is based on clinical presentation, ie, spontaneously recurring wheals, angioedema, or both. Chronic spontaneous urticaria p …
Urticaria and Angioedema: an Update on Classification and Pathogenesis.
Radonjic-Hoesli S, Hofmeier KS, Micaletto S, Schmid-Grendelmeier P, Bircher A, Simon D. Radonjic-Hoesli S, et al. Clin Rev Allergy Immunol. 2018 Feb;54(1):88-101. doi: 10.1007/s12016-017-8628-1. Clin Rev Allergy Immunol. 2018. PMID: 28748365 Free article. Review.
Urticaria is a common, mast cell-driven disease presenting with wheals or angioedema or both. In the last years, urticaria has increasingly attracted notice to clinicians and researchers, last but not least inspired by the approval of omalizumab, an anti-IgE antibody, for …
Urticaria is a common, mast cell-driven disease presenting with wheals or angioedema or both. In the last years, urticaria has increa …
Angioedema without urticaria: Diagnosis and management.
Young MC, Banerji A. Young MC, et al. Allergy Asthma Proc. 2025 May 1;46(3):185-191. doi: 10.2500/aap.2025.46.250013. Allergy Asthma Proc. 2025. PMID: 40380367 Review.
Bradykinin-mediated angioedema presents without urticaria, whereas histaminergic angioedema is usually associated with urticaria (i.e., chronic spontaneous urticaria and angioedema) but manifests with isolated angioedema in 20% of patients and clinica …
Bradykinin-mediated angioedema presents without urticaria, whereas histaminergic angioedema is usually associated with urticar …
Endotypes of chronic spontaneous urticaria and angioedema.
Wong D, Waserman S, Sussman GL. Wong D, et al. J Allergy Clin Immunol. 2025 Jul;156(1):17-23. doi: 10.1016/j.jaci.2025.04.004. Epub 2025 Apr 10. J Allergy Clin Immunol. 2025. PMID: 40220911 Free article. Review.
The current understanding of chronic spontaneous urticaria (CSU) suggests that a complex network of inflammatory pathways is involved in its pathogenesis. Recent development highlighted autoimmunity as one of the key pathogenic mechanisms of CSU. Two endotypes, type I auto …
The current understanding of chronic spontaneous urticaria (CSU) suggests that a complex network of inflammatory pathways is involved in its …
CRISPR-Based Therapy for Hereditary Angioedema.
Cohn DM, Gurugama P, Magerl M, Katelaris CH, Launay D, Bouillet L, Petersen RS, Lindsay K, Aygören-Pürsün E, Maag D, Butler JS, Shah MY, Golden A, Xu Y, Abdelhady AM, Lebwohl D, Longhurst HJ. Cohn DM, et al. N Engl J Med. 2025 Jan 30;392(5):458-467. doi: 10.1056/NEJMoa2405734. Epub 2024 Oct 24. N Engl J Med. 2025. PMID: 39445704 Clinical Trial.
BACKGROUND: Hereditary angioedema is a rare genetic disease characterized by severe and unpredictable swelling attacks. ...CONCLUSIONS: NTLA-2002 administered in a single dose of 25 mg or 50 mg reduced angioedema attacks and led to robust and sustained reduction in …
BACKGROUND: Hereditary angioedema is a rare genetic disease characterized by severe and unpredictable swelling attacks. ...CONCLUSION …
Angioedema.
Kaplan AP, Greaves MW. Kaplan AP, et al. J Am Acad Dermatol. 2005 Sep;53(3):373-88; quiz 389-92. doi: 10.1016/j.jaad.2004.09.032. J Am Acad Dermatol. 2005. PMID: 16112343 Review.
Angioedema caused by a C'1 esterase inhibitor deficiency can also be acquired in several clinical settings, including lymphoma and autoimmune connective tissue disease. ...We have reviewed the clinical features, diagnosis, and management of these different subtypes …
Angioedema caused by a C'1 esterase inhibitor deficiency can also be acquired in several clinical settings, including lymphoma and …
The autoimmune side of hereditary angioedema: insights on the pathogenesis.
Triggianese P, Chimenti MS, Toubi E, Ballanti E, Guarino MD, Perricone C, Perricone R. Triggianese P, et al. Autoimmun Rev. 2015 Aug;14(8):665-9. doi: 10.1016/j.autrev.2015.03.006. Epub 2015 Mar 28. Autoimmun Rev. 2015. PMID: 25827463 Review.
In HAE, the potential inadequate clearance of immune-complexes (IC) in the presence of reduced levels of CS components and in turn an excess of IC in the tissues results in inflammatory damage and release of autoantigens that may trigger an autoimmune response. Occasional …
In HAE, the potential inadequate clearance of immune-complexes (IC) in the presence of reduced levels of CS components and in turn an excess …
Autoimmune angioedema: a new role for autoantibody in disease pathogenesis.
Jackson J, Feighery C. Jackson J, et al. Autoimmunity. 1990;7(2-3):181-7. doi: 10.3109/08916939008993390. Autoimmunity. 1990. PMID: 2104184 Free article. Review.
Angioedema may be due to hereditary forms of Cl-Inh deficiency, but recently an autoimmune form of angioedema has been described in which the mechanism is novel. While the peripheral blood monocytes of patients with autoimmune angioedema produce …
Angioedema may be due to hereditary forms of Cl-Inh deficiency, but recently an autoimmune form of angioedema has been …
Chronic Spontaneous Urticaria: The Devil's Itch.
Saini SS, Kaplan AP. Saini SS, et al. J Allergy Clin Immunol Pract. 2018 Jul-Aug;6(4):1097-1106. doi: 10.1016/j.jaip.2018.04.013. J Allergy Clin Immunol Pract. 2018. PMID: 30033911 Free PMC article. Review.
A search for such an external "cause" is fruitless because the underlying abnormality is "intrinsic," whether it is autoimmune, or some unknown process. Approximately 40% of patients with chronic spontaneous urticaria report accompanying episodes of angioedema, wher …
A search for such an external "cause" is fruitless because the underlying abnormality is "intrinsic," whether it is autoimmune, or so …
623 results