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In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue.
Houten SM, Volle DH, Cummins CL, Mangelsdorf DJ, Auwerx J. Houten SM, et al. Among authors: auwerx j. Mol Endocrinol. 2007 Jun;21(6):1312-23. doi: 10.1210/me.2007-0113. Epub 2007 Apr 10. Mol Endocrinol. 2007. PMID: 17426284
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors.
Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, Auwerx J, Mangelsdorf DJ. Lu TT, et al. Among authors: auwerx j. Mol Cell. 2000 Sep;6(3):507-15. doi: 10.1016/s1097-2765(00)00050-2. Mol Cell. 2000. PMID: 11030331
Uses of forward and reverse genetics in mice to study gene function.
Argmann CA, Dierich A, Auwerx J. Argmann CA, et al. Among authors: auwerx j. Curr Protoc Mol Biol. 2006 Feb;Chapter 29:Unit 29A.1. doi: 10.1002/0471142727.mb29a01s73. Curr Protoc Mol Biol. 2006. PMID: 18265381
Ppargamma2 is a key driver of longevity in the mouse.
Argmann C, Dobrin R, Heikkinen S, Auburtin A, Pouilly L, Cock TA, Koutnikova H, Zhu J, Schadt EE, Auwerx J. Argmann C, et al. Among authors: auwerx j. PLoS Genet. 2009 Dec;5(12):e1000752. doi: 10.1371/journal.pgen.1000752. Epub 2009 Dec 4. PLoS Genet. 2009. PMID: 19997628 Free PMC article.
Transcriptional coregulators in the control of energy homeostasis.
Feige JN, Auwerx J. Feige JN, et al. Among authors: auwerx j. Trends Cell Biol. 2007 Jun;17(6):292-301. doi: 10.1016/j.tcb.2007.04.001. Epub 2007 May 1. Trends Cell Biol. 2007. PMID: 17475497 Review.
Targeting bile-acid signalling for metabolic diseases.
Thomas C, Pellicciari R, Pruzanski M, Auwerx J, Schoonjans K. Thomas C, et al. Among authors: auwerx j. Nat Rev Drug Discov. 2008 Aug;7(8):678-93. doi: 10.1038/nrd2619. Nat Rev Drug Discov. 2008. PMID: 18670431 Review.
Lipid and bile acid analysis.
Argmann CA, Houten SM, Champy MF, Auwerx J. Argmann CA, et al. Among authors: auwerx j. Curr Protoc Mol Biol. 2006 Aug;Chapter 29:Unit 29B.2. doi: 10.1002/0471142727.mb29b02s75. Curr Protoc Mol Biol. 2006. PMID: 18265385
Sirtuin functions in health and disease.
Yamamoto H, Schoonjans K, Auwerx J. Yamamoto H, et al. Among authors: auwerx j. Mol Endocrinol. 2007 Aug;21(8):1745-55. doi: 10.1210/me.2007-0079. Epub 2007 Apr 24. Mol Endocrinol. 2007. PMID: 17456799 Review.
LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling.
Terrand J, Bruban V, Zhou L, Gong W, El Asmar Z, May P, Zurhove K, Haffner P, Philippe C, Woldt E, Matz RL, Gracia C, Metzger D, Auwerx J, Herz J, Boucher P. Terrand J, et al. Among authors: auwerx j. J Biol Chem. 2009 Jan 2;284(1):381-8. doi: 10.1074/jbc.M806538200. Epub 2008 Nov 6. J Biol Chem. 2009. PMID: 18990694 Free PMC article.
LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.
Boucher P, Li WP, Matz RL, Takayama Y, Auwerx J, Anderson RG, Herz J. Boucher P, et al. Among authors: auwerx j. PLoS One. 2007 May 16;2(5):e448. doi: 10.1371/journal.pone.0000448. PLoS One. 2007. PMID: 17505534 Free PMC article.
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