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The evolutionary genomics of pathogen recombination.
Awadalla P. Awadalla P. Nat Rev Genet. 2003 Jan;4(1):50-60. doi: 10.1038/nrg964. Nat Rev Genet. 2003. PMID: 12509753 Review.
Recombination affects accumulation of damaging and disease-associated mutations in human populations.
Hussin JG, Hodgkinson A, Idaghdour Y, Grenier JC, Goulet JP, Gbeha E, Hip-Ki E, Awadalla P. Hussin JG, et al. Among authors: awadalla p. Nat Genet. 2015 Apr;47(4):400-4. doi: 10.1038/ng.3216. Epub 2015 Feb 16. Nat Genet. 2015. PMID: 25685891
Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome.
Mu J, Awadalla P, Duan J, McGee KM, Keebler J, Seydel K, McVean GA, Su XZ. Mu J, et al. Among authors: awadalla p. Nat Genet. 2007 Jan;39(1):126-30. doi: 10.1038/ng1924. Epub 2006 Dec 10. Nat Genet. 2007. PMID: 17159981
Here we surveyed 3,539 P. falciparum genes ( approximately 65% of the predicted genes) for polymorphisms and identified various highly polymorphic loci and genes, some of which encode new antigens that we confirmed using human immune sera. ...
Here we surveyed 3,539 P. falciparum genes ( approximately 65% of the predicted genes) for polymorphisms and identified various highl …
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs.
Mu J, Myers RA, Jiang H, Liu S, Ricklefs S, Waisberg M, Chotivanich K, Wilairatana P, Krudsood S, White NJ, Udomsangpetch R, Cui L, Ho M, Ou F, Li H, Song J, Li G, Wang X, Seila S, Sokunthea S, Socheat D, Sturdevant DE, Porcella SF, Fairhurst RM, Wellems TE, Awadalla P, Su XZ. Mu J, et al. Among authors: awadalla p. Nat Genet. 2010 Mar;42(3):268-71. doi: 10.1038/ng.528. Epub 2010 Jan 31. Nat Genet. 2010. PMID: 20101240 Free PMC article.
Here we report the first Plasmodium GWAS, which included 189 culture-adapted P. falciparum parasites genotyped using a custom-built Affymetrix molecular inversion probe 3K malaria panel array with a coverage of approximately 1 SNP per 7 kb. ...This study provides valuable …
Here we report the first Plasmodium GWAS, which included 189 culture-adapted P. falciparum parasites genotyped using a custom-built A …
Diversity and linkage of genes in the self-incompatibility gene family in Arabidopsis lyrata.
Charlesworth D, Mable BK, Schierup MH, Bartolomé C, Awadalla P. Charlesworth D, et al. Among authors: awadalla p. Genetics. 2003 Aug;164(4):1519-35. Genetics. 2003. PMID: 12930757 Free PMC article.
A coalescent-based method for detecting and estimating recombination from gene sequences.
McVean G, Awadalla P, Fearnhead P. McVean G, et al. Among authors: awadalla p. Genetics. 2002 Mar;160(3):1231-41. Genetics. 2002. PMID: 11901136 Free PMC article.
Recombination and selection at Brassica self-incompatibility loci.
Awadalla P, Charlesworth D. Awadalla P, et al. Genetics. 1999 May;152(1):413-25. Genetics. 1999. PMID: 10224271 Free PMC article.
Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus.
Barbash DA, Awadalla P, Tarone AM. Barbash DA, et al. Among authors: awadalla p. PLoS Biol. 2004 Jun;2(6):e142. doi: 10.1371/journal.pbio.0020142. Epub 2004 Jun 15. PLoS Biol. 2004. PMID: 15208709 Free PMC article.
Relaxed Selection During a Recent Human Expansion.
Peischl S, Dupanloup I, Foucal A, Jomphe M, Bruat V, Grenier JC, Gouy A, Gilbert KJ, Gbeha E, Bosshard L, Hip-Ki E, Agbessi M, Hodgkinson A, Vézina H, Awadalla P, Excoffier L. Peischl S, et al. Among authors: awadalla p. Genetics. 2018 Feb;208(2):763-777. doi: 10.1534/genetics.117.300551. Epub 2017 Nov 29. Genetics. 2018. PMID: 29187508 Free PMC article.
Does human mtDNA recombine?
Eyre-Walker A, Awadalla P. Eyre-Walker A, et al. Among authors: awadalla p. J Mol Evol. 2001 Oct-Nov;53(4-5):430-5. doi: 10.1007/s002390010232. J Mol Evol. 2001. PMID: 11675602 Review.
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