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Rare allelic forms of PRDM9 associated with childhood leukemogenesis.
Hussin J, Sinnett D, Casals F, Idaghdour Y, Bruat V, Saillour V, Healy J, Grenier JC, de Malliard T, Busche S, Spinella JF, Larivière M, Gibson G, Andersson A, Holmfeldt L, Ma J, Wei L, Zhang J, Andelfinger G, Downing JR, Mullighan CG, Awadalla P. Hussin J, et al. Among authors: awadalla p. Genome Res. 2013 Mar;23(3):419-30. doi: 10.1101/gr.144188.112. Epub 2012 Dec 5. Genome Res. 2013. PMID: 23222848 Free PMC article.
Age-dependent recombination rates in human pedigrees.
Hussin J, Roy-Gagnon MH, Gendron R, Andelfinger G, Awadalla P. Hussin J, et al. Among authors: awadalla p. PLoS Genet. 2011 Sep;7(9):e1002251. doi: 10.1371/journal.pgen.1002251. Epub 2011 Sep 1. PLoS Genet. 2011. PMID: 21912527 Free PMC article.
Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans.
Casals F, Hodgkinson A, Hussin J, Idaghdour Y, Bruat V, de Maillard T, Grenier JC, Gbeha E, Hamdan FF, Girard S, Spinella JF, Larivière M, Saillour V, Healy J, Fernández I, Sinnett D, Michaud JL, Rouleau GA, Haddad E, Le Deist F, Awadalla P. Casals F, et al. Among authors: awadalla p. PLoS Genet. 2013;9(9):e1003815. doi: 10.1371/journal.pgen.1003815. Epub 2013 Sep 26. PLoS Genet. 2013. PMID: 24086152 Free PMC article.
The impact of recombination on human mutation load and disease.
Alves I, Houle AA, Hussin JG, Awadalla P. Alves I, et al. Among authors: awadalla p. Philos Trans R Soc Lond B Biol Sci. 2017 Dec 19;372(1736):20160465. doi: 10.1098/rstb.2016.0465. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 29109227 Free PMC article. Review.
Aberrant PRDM9 expression impacts the pan-cancer genomic landscape.
Houle AA, Gibling H, Lamaze FC, Edgington HA, Soave D, Fave MJ, Agbessi M, Bruat V, Stein LD, Awadalla P. Houle AA, et al. Among authors: awadalla p. Genome Res. 2018 Nov;28(11):1611-1620. doi: 10.1101/gr.231696.117. Epub 2018 Oct 19. Genome Res. 2018. PMID: 30341163 Free PMC article.
A population genetic approach to mapping neurological disorder genes using deep resequencing.
Myers RA, Casals F, Gauthier J, Hamdan FF, Keebler J, Boyko AR, Bustamante CD, Piton AM, Spiegelman D, Henrion E, Zilversmit M, Hussin J, Quinlan J, Yang Y, Lafrenière RG, Griffing AR, Stone EA, Rouleau GA, Awadalla P. Myers RA, et al. Among authors: awadalla p. PLoS Genet. 2011 Feb;7(2):e1001318. doi: 10.1371/journal.pgen.1001318. Epub 2011 Feb 24. PLoS Genet. 2011. PMID: 21383861 Free PMC article.
181 results