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Prediction of acute myeloid leukaemia risk in healthy individuals.
Abelson S, Collord G, Ng SWK, Weissbrod O, Mendelson Cohen N, Niemeyer E, Barda N, Zuzarte PC, Heisler L, Sundaravadanam Y, Luben R, Hayat S, Wang TT, Zhao Z, Cirlan I, Pugh TJ, Soave D, Ng K, Latimer C, Hardy C, Raine K, Jones D, Hoult D, Britten A, McPherson JD, Johansson M, Mbabaali F, Eagles J, Miller JK, Pasternack D, Timms L, Krzyzanowski P, Awadalla P, Costa R, Segal E, Bratman SV, Beer P, Behjati S, Martincorena I, Wang JCY, Bowles KM, Quirós JR, Karakatsani A, La Vecchia C, Trichopoulou A, Salamanca-Fernández E, Huerta JM, Barricarte A, Travis RC, Tumino R, Masala G, Boeing H, Panico S, Kaaks R, Krämer A, Sieri S, Riboli E, Vineis P, Foll M, McKay J, Polidoro S, Sala N, Khaw KT, Vermeulen R, Campbell PJ, Papaemmanuil E, Minden MD, Tanay A, Balicer RD, Wareham NJ, Gerstung M, Dick JE, Brennan P, Vassiliou GS, Shlush LI. Abelson S, et al. Nature. 2018 Jul;559(7714):400-404. doi: 10.1038/s41586-018-0317-6. Epub 2018 Jul 9. Nature. 2018. PMID: 29988082 Free PMC article.
Variation in genome-wide mutation rates within and between human families.
Conrad DF, Keebler JE, DePristo MA, Lindsay SJ, Zhang Y, Casals F, Idaghdour Y, Hartl CL, Torroja C, Garimella KV, Zilversmit M, Cartwright R, Rouleau GA, Daly M, Stone EA, Hurles ME, Awadalla P; 1000 Genomes Project. Conrad DF, et al. Nat Genet. 2011 Jun 12;43(7):712-4. doi: 10.1038/ng.862. Nat Genet. 2011. PMID: 21666693 Free PMC article.
Gene-by-environment interactions in urban populations modulate risk phenotypes.
Favé MJ, Lamaze FC, Soave D, Hodgkinson A, Gauvin H, Bruat V, Grenier JC, Gbeha E, Skead K, Smargiassi A, Johnson M, Idaghdour Y, Awadalla P. Favé MJ, et al. Nat Commun. 2018 Mar 6;9(1):827. doi: 10.1038/s41467-018-03202-2. Nat Commun. 2018. PMID: 29511166 Free PMC article.
Allele-specific expression reveals interactions between genetic variation and environment.
Knowles DA, Davis JR, Edgington H, Raj A, Favé MJ, Zhu X, Potash JB, Weissman MM, Shi J, Levinson DF, Awadalla P, Mostafavi S, Montgomery SB, Battle A. Knowles DA, et al. Nat Methods. 2017 Jul;14(7):699-702. doi: 10.1038/nmeth.4298. Epub 2017 May 22. Nat Methods. 2017. PMID: 28530654 Free PMC article.
Aberrant PRDM9 expression impacts the pan-cancer genomic landscape.
Houle AA, Gibling H, Lamaze FC, Edgington HA, Soave D, Fave MJ, Agbessi M, Bruat V, Stein LD, Awadalla P. Houle AA, et al. Genome Res. 2018 Nov;28(11):1611-1620. doi: 10.1101/gr.231696.117. Epub 2018 Oct 19. Genome Res. 2018. PMID: 30341163 Free PMC article.
The impact of recombination on human mutation load and disease.
Alves I, Houle AA, Hussin JG, Awadalla P. Alves I, et al. Philos Trans R Soc Lond B Biol Sci. 2017 Dec 19;372(1736):20160465. doi: 10.1098/rstb.2016.0465. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 29109227 Free PMC article. Review.
Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion.
Troyanov S, Delmas-Frenette C, Bollée G, Youhanna S, Bruat V, Awadalla P, Devuyst O, Madore F. Troyanov S, et al. Clin J Am Soc Nephrol. 2016 Jan 7;11(1):62-9. doi: 10.2215/CJN.04770415. Epub 2015 Dec 18. Clin J Am Soc Nephrol. 2016. PMID: 26683887 Free PMC article.
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