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Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors.
Delaney JR, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR, Stupack DG. Delaney JR, et al. Among authors: axelrod j. PLoS Genet. 2020 Jan 10;16(1):e1008558. doi: 10.1371/journal.pgen.1008558. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31923184 Free PMC article.
Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.
Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG. Delaney JR, et al. Among authors: axelrod j. Nat Commun. 2017 Feb 15;8:14423. doi: 10.1038/ncomms14423. Nat Commun. 2017. PMID: 28198375 Free PMC article.
Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy.
Xu H, Tong Z, Ye Q, Sun T, Hong Z, Zhang L, Bortnick A, Cho S, Beuzer P, Axelrod J, Hu Q, Wang M, Evans SM, Murre C, Lu LF, Sun S, Corbett KD, Cang H. Xu H, et al. Among authors: axelrod j. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18423-18428. doi: 10.1073/pnas.1902440116. Epub 2019 Aug 23. Proc Natl Acad Sci U S A. 2019. PMID: 31444302 Free PMC article.
Single dish gradient screening of small molecule localization.
Beuzer P, Axelrod J, Trzoss L, Fenical W, Dasari R, Evidente A, Kornienko A, Cang H, La Clair JJ. Beuzer P, et al. Among authors: axelrod j. Org Biomol Chem. 2016 Sep 21;14(35):8241-5. doi: 10.1039/c6ob01418f. Epub 2016 Aug 17. Org Biomol Chem. 2016. PMID: 27530345 Free PMC article.
743 results