Aylon Y - Search Results

1

LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state.

Furth N, Pateras IS, Rotkopf R, Vlachou V, Rivkin I, Schmitt I, Bakaev D, Gershoni A, Ainbinder E, Leshkowitz D, Johnson RL, Gorgoulis VG, Oren M, Aylon Y. Furth N, et al. Among authors: aylon y. Life Sci Alliance. 2018 Oct 30;1(5):e201800171. doi: 10.26508/lsa.201800171. eCollection 2018 Oct. Life Sci Alliance. 2018. PMID: 30456386 Free PMC article.

2

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization.

Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, Oren M. Aylon Y, et al. Genes Dev. 2006 Oct 1;20(19):2687-700. doi: 10.1101/gad.1447006. Genes Dev. 2006. PMID: 17015431 Free PMC article.

3

Living with p53, dying of p53.

Aylon Y, Oren M. Aylon Y, et al. Cell. 2007 Aug 24;130(4):597-600. doi: 10.1016/j.cell.2007.08.005. Cell. 2007. PMID: 17719538 Free article. Review.

4

Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.

Finkin S, Aylon Y, Anzi S, Oren M, Shaulian E. Finkin S, et al. Among authors: aylon y. Oncogene. 2008 Jul 24;27(32):4411-21. doi: 10.1038/onc.2008.77. Epub 2008 Apr 7. Oncogene. 2008. PMID: 18391985

5

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.

Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M. Shema E, et al. Among authors: aylon y. Genes Dev. 2008 Oct 1;22(19):2664-76. doi: 10.1101/gad.1703008. Genes Dev. 2008. PMID: 18832071 Free PMC article.

6

Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation.

Aylon Y, Yabuta N, Besserglick H, Buganim Y, Rotter V, Nojima H, Oren M. Aylon Y, et al. Oncogene. 2009 Dec 17;28(50):4469-79. doi: 10.1038/onc.2009.270. Epub 2009 Oct 26. Oncogene. 2009. PMID: 19855428 Free PMC article.

7

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1.

Aylon Y, Ofir-Rosenfeld Y, Yabuta N, Lapi E, Nojima H, Lu X, Oren M. Aylon Y, et al. Genes Dev. 2010 Nov 1;24(21):2420-9. doi: 10.1101/gad.1954410. Genes Dev. 2010. PMID: 21041410 Free PMC article.

8

A novel Chk1/2-Lats2-14-3-3 signaling pathway regulates P-body formation in response to UV damage.

Okada N, Yabuta N, Suzuki H, Aylon Y, Oren M, Nojima H. Okada N, et al. Among authors: aylon y. J Cell Sci. 2011 Jan 1;124(Pt 1):57-67. doi: 10.1242/jcs.072918. Epub 2010 Nov 30. J Cell Sci. 2011. PMID: 21118956

9

New plays in the p53 theater.

Aylon Y, Oren M. Aylon Y, et al. Curr Opin Genet Dev. 2011 Feb;21(1):86-92. doi: 10.1016/j.gde.2010.10.002. Epub 2010 Nov 4. Curr Opin Genet Dev. 2011. PMID: 21317061 Free PMC article. Review.

10

p53: guardian of ploidy.

Aylon Y, Oren M. Aylon Y, et al. Mol Oncol. 2011 Aug;5(4):315-23. doi: 10.1016/j.molonc.2011.07.007. Epub 2011 Jul 30. Mol Oncol. 2011. PMID: 21852209 Free PMC article. Review.

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