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Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.
Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Lévy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P. Ichimura A, et al. Among authors: ayukawa k. Nature. 2012 Feb 19;483(7389):350-4. doi: 10.1038/nature10798. Nature. 2012. PMID: 22343897 Free article.
High-Throughput Screening for Linear Ubiquitin Chain Assembly Complex (LUBAC) Selective Inhibitors Using Homogenous Time-Resolved Fluorescence (HTRF)-Based Assay System.
Katsuya K, Hori Y, Oikawa D, Yamamoto T, Umetani K, Urashima T, Kinoshita T, Ayukawa K, Tokunaga F, Tamaru M. Katsuya K, et al. Among authors: ayukawa k. SLAS Discov. 2018 Dec;23(10):1018-1029. doi: 10.1177/2472555218793066. Epub 2018 Aug 2. SLAS Discov. 2018. PMID: 30071751 Free article.
Phenotypic Screening for Small Molecules that Protect β-Cells from Glucolipotoxicity.
Small JC, Joblin-Mills A, Carbone K, Kost-Alimova M, Ayukawa K, Khodier C, Dancik V, Clemons PA, Munkacsi AB, Wagner BK. Small JC, et al. Among authors: ayukawa k. ACS Chem Biol. 2022 May 20;17(5):1131-1142. doi: 10.1021/acschembio.2c00052. Epub 2022 Apr 19. ACS Chem Biol. 2022. PMID: 35439415 Free PMC article.
Phase II study of ceritinib in alectinib-pretreated patients with anaplastic lymphoma kinase-rearranged metastatic non-small-cell lung cancer in Japan: ASCEND-9.
Hida T, Seto T, Horinouchi H, Maemondo M, Takeda M, Hotta K, Hirai F, Kim YH, Matsumoto S, Ito M, Ayukawa K, Tokushige K, Yonemura M, Mitsudomi T, Nishio M. Hida T, et al. Among authors: ayukawa k. Cancer Sci. 2018 Sep;109(9):2863-2872. doi: 10.1111/cas.13721. Epub 2018 Jul 25. Cancer Sci. 2018. PMID: 29959809 Free PMC article. Clinical Trial.
Calcium channel blocker attenuated opioid withdrawal syndrome.
Shimatani T, Adachi H, Mihashi H, Usumoto N, Yoshimoto K, Ayukawa K. Shimatani T, et al. Among authors: ayukawa k. Acute Med Surg. 2014 Aug 8;2(2):114-116. doi: 10.1002/ams2.72. eCollection 2015 Apr. Acute Med Surg. 2014. PMID: 29123703 Free PMC article.
45 results