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Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins.
Pirazzini M, Azarnia Tehran D, Zanetti G, Megighian A, Scorzeto M, Fillo S, Shone CC, Binz T, Rossetto O, Lista F, Montecucco C. Pirazzini M, et al. Among authors: azarnia tehran d. Cell Rep. 2014 Sep 25;8(6):1870-1878. doi: 10.1016/j.celrep.2014.08.017. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220457 Free article.
Erratum to "Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism" [Biochem. Pharmacol. 98 (2015) 522-530].
Zanetti G, Azarnia Tehran D, Pirazzini M, Binz T, Shone CC, Fillo S, Lista F, Rossetto O, Montecucco C. Zanetti G, et al. Among authors: azarnia tehran d. Biochem Pharmacol. 2016 Sep 1;115:152. doi: 10.1016/j.bcp.2016.07.006. Epub 2016 Jul 12. Biochem Pharmacol. 2016. PMID: 27498956 No abstract available.
Genomic characterization of Italian Clostridium botulinum group I strains.
Giordani F, Fillo S, Anselmo A, Palozzi AM, Fortunato A, Gentile B, Azarnia Tehran D, Ciammaruconi A, Spagnolo F, Pittiglio V, Anniballi F, Auricchio B, De Medici D, Lista F. Giordani F, et al. Among authors: azarnia tehran d. Infect Genet Evol. 2015 Dec;36:62-71. doi: 10.1016/j.meegid.2015.08.042. Epub 2015 Sep 1. Infect Genet Evol. 2015. PMID: 26341861
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