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Cholesterol crystals cause mechanical damage to biological membranes: a proposed mechanism of plaque rupture and erosion leading to arterial thrombosis.
Abela GS, Aziz K. Abela GS, et al. Among authors: aziz k. Clin Cardiol. 2005 Sep;28(9):413-20. doi: 10.1002/clc.4960280906. Clin Cardiol. 2005. PMID: 16250264 Free PMC article.
Arterial wall cholesterol content is a predictor of development and severity of arterial thrombosis.
Ma H, Aziz KS, Huang R, Abela GS. Ma H, et al. Among authors: aziz ks. J Thromb Thrombolysis. 2006 Aug;22(1):5-11. doi: 10.1007/s11239-006-7861-x. J Thromb Thrombolysis. 2006. PMID: 16786227
Noninvasive detection and localization of vulnerable plaque and arterial thrombosis with computed tomography angiography/positron emission tomography.
Aziz K, Berger K, Claycombe K, Huang R, Patel R, Abela GS. Aziz K, et al. Circulation. 2008 Apr 22;117(16):2061-70. doi: 10.1161/CIRCULATIONAHA.106.652313. Epub 2008 Apr 7. Circulation. 2008. PMID: 18391115
Plaque rupture and thrombosis are reduced by lowering cholesterol levels and crystallization with ezetimibe and are correlated with fluorodeoxyglucose positron emission tomography.
Patel R, Janoudi A, Vedre A, Aziz K, Tamhane U, Rubinstein J, Abela OG, Berger K, Abela GS. Patel R, et al. Among authors: aziz k. Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2007-14. doi: 10.1161/ATVBAHA.111.226167. Epub 2011 Aug 4. Arterioscler Thromb Vasc Biol. 2011. PMID: 21817102
Effect of cholesterol crystals on plaques and intima in arteries of patients with acute coronary and cerebrovascular syndromes.
Abela GS, Aziz K, Vedre A, Pathak DR, Talbott JD, Dejong J. Abela GS, et al. Among authors: aziz k. Am J Cardiol. 2009 Apr 1;103(7):959-68. doi: 10.1016/j.amjcard.2008.12.019. Epub 2009 Feb 7. Am J Cardiol. 2009. PMID: 19327423
Cholesterol crystals rupture biological membranes and human plaques during acute cardiovascular events--a novel insight into plaque rupture by scanning electron microscopy.
Abela GS, Aziz K. Abela GS, et al. Among authors: aziz k. Scanning. 2006 Jan-Feb;28(1):1-10. doi: 10.1002/sca.4950280101. Scanning. 2006. PMID: 16502619
Update on coronary angioscopy: review of a 20-year experience and potential application for detection of vulnerable plaque.
Ishibashi F, Aziz K, Abela GS, Waxman S. Ishibashi F, et al. Among authors: aziz k. J Interv Cardiol. 2006 Feb;19(1):17-25. doi: 10.1111/j.1540-8183.2006.00099.x. J Interv Cardiol. 2006. PMID: 16483335 Review.
Integration of clinical and imaging data to predict the presence of coronary artery disease with the use of neural networks.
Scott JA, Aziz K, Yasuda T, Gewirtz H. Scott JA, et al. Among authors: aziz k. Coron Artery Dis. 2004 Nov;15(7):427-34. doi: 10.1097/00019501-200411000-00010. Coron Artery Dis. 2004. PMID: 15492592
High-dose folic acid acutely improves coronary vasodilator function in patients with coronary artery disease.
Tawakol A, Migrino RQ, Aziz KS, Waitkowska J, Holmvang G, Alpert NM, Muller JE, Fischman AJ, Gewirtz H. Tawakol A, et al. Among authors: aziz ks. J Am Coll Cardiol. 2005 May 17;45(10):1580-4. doi: 10.1016/j.jacc.2005.02.038. Epub 2005 Apr 26. J Am Coll Cardiol. 2005. PMID: 15893170 Free PMC article. Clinical Trial.
Myocardial blood flow and oxygen consumption in patients with Friedreich's ataxia prior to the onset of cardiomyopathy.
Gregory SA, MacRae CA, Aziz K, Sims KB, Schmahmann JD, Kardan A, Morss AM, Ellinor PT, Tawakol A, Fischman AJ, Gewirtz H. Gregory SA, et al. Among authors: aziz k. Coron Artery Dis. 2007 Feb;18(1):15-22. doi: 10.1097/01.mca.0000236289.02178.60. Coron Artery Dis. 2007. PMID: 17172925
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