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Page 1
Apolipoprotein C3 facilitates internalization of cationic lipid nanoparticles into bone marrow-derived mouse mast cells.
Alam SB, Wang F, Qian H, Kulka M. Alam SB, et al. Sci Rep. 2023 Jan 9;13(1):431. doi: 10.1038/s41598-022-25737-7. Sci Rep. 2023. PMID: 36624108 Free PMC article.
LNP preparations made up of DODMA or DODMA, DODAP and DOTAP lipids were coated with seven apolipoproteins (Apo A1, B, C3, D, E2, E4 and H). Differentiated bone-marrow derived mouse mast cells (BMMCs) were exposed to apolipoprotein-LNP and internalization was measure …
LNP preparations made up of DODMA or DODMA, DODAP and DOTAP lipids were coated with seven apolipoproteins (Apo A1, B, C3, D, E …
Effects of intravenous butaphosphan and cyanocobalamin to late pregnant ewes on the metabolic indices around parturition and weight gain of their lambs after birth.
Mohammadi Barimanloo A, Chalmeh A, Pourjafar M, Mirzaei A. Mohammadi Barimanloo A, et al. Vet Med Sci. 2022 Mar;8(2):781-791. doi: 10.1002/vms3.687. Epub 2021 Dec 13. Vet Med Sci. 2022. PMID: 34904397 Free PMC article.
METHODS: Twenty-eight clinically healthy 3-year-old pregnant Afshari ewes from 21 days before parturition were enrolled into four equal groups: control (Ctrl), B+C1, B+C2 and B+C3. The Ctrl group only received intravenous normal saline and B+C1, B+C2 and B+ …
METHODS: Twenty-eight clinically healthy 3-year-old pregnant Afshari ewes from 21 days before parturition were enrolled into four equal grou …
Properdin Is a Key Player in Lysis of Red Blood Cells and Complement Activation on Endothelial Cells in Hemolytic Anemias Caused by Complement Dysregulation.
Chen JY, Galwankar NS, Emch HN, Menon SS, Cortes C, Thurman JM, Merrill SA, Brodsky RA, Ferreira VP. Chen JY, et al. Front Immunol. 2020 Jul 22;11:1460. doi: 10.3389/fimmu.2020.01460. eCollection 2020. Front Immunol. 2020. PMID: 32793201 Free PMC article.
In in vitro models of PNH, properdin inhibition prevented hemolysis of patient PNH type II and III RBCs more than inhibition of Factor B, C3, and C5 (>17-fold, or >81-fold, or >12-fold lower molar IC(90) values, respectively). ...
In in vitro models of PNH, properdin inhibition prevented hemolysis of patient PNH type II and III RBCs more than inhibition of Factor B …
Synthesis and catalytic activity of heteroatom doped metal-free single-wall carbon nanohorns.
Wu X, Cui L, Tang P, Hu Z, Ma D, Shi Z. Wu X, et al. Chem Commun (Camb). 2016 Apr 7;52(31):5391-3. doi: 10.1039/c5cc10683d. Chem Commun (Camb). 2016. PMID: 27006980
These as-prepared doped materials consist of uniform isolated nanohorns and exhibit greatly enhanced catalytic capabilities in the reduction reaction of nitrobenzene and a volcano-shape trend between their activities with a B dopant content is found. Moreover, the B-C3 …
These as-prepared doped materials consist of uniform isolated nanohorns and exhibit greatly enhanced catalytic capabilities in the reduction …
Case report: lupus nephritis with autoantibodies to complement alternative pathway proteins and C3 gene mutation.
Nozal P, Garrido S, Martínez-Ara J, Picazo ML, Yébenes L, Álvarez-Doforno R, Pinto S, de Córdoba SR, López-Trascasa M. Nozal P, et al. BMC Nephrol. 2015 Mar 30;16:40. doi: 10.1186/s12882-015-0032-6. BMC Nephrol. 2015. PMID: 25886501 Free PMC article.
Serial sera samples were analyzed, and autoantibodies to complement alternative pathway proteins (Factor I, Factor B, C3 and Properdin) were found. Functional assays showed that these autoantibodies cause alternative pathway activation. CONCLUSION: This case is the …
Serial sera samples were analyzed, and autoantibodies to complement alternative pathway proteins (Factor I, Factor B, C3 and P …
Temporal transcriptome analysis of the chicken embryo yolk sac.
Yadgary L, Wong EA, Uni Z. Yadgary L, et al. BMC Genomics. 2014 Aug 19;15(1):690. doi: 10.1186/1471-2164-15-690. BMC Genomics. 2014. PMID: 25141977 Free PMC article.
Several lysosomal genes (CTSA, PSAP, NPC2) and apolipoproteins genes (apoA1, A2, B, C3) were among the highest expressed, reflecting the intensive digestion and re-synthesis of lipoproteins in YS epithelial cells. ...
Several lysosomal genes (CTSA, PSAP, NPC2) and apolipoproteins genes (apoA1, A2, B, C3) were among the highest expressed, refl …
Monobenzofused 1,4-azaborines: synthesis, characterization, and discovery of a unique coordination mode.
Xu S, Haeffner F, Li B, Zakharov LN, Liu SY. Xu S, et al. Angew Chem Int Ed Engl. 2014 Jun 23;53(26):6795-9. doi: 10.1002/anie.201403903. Epub 2014 May 18. Angew Chem Int Ed Engl. 2014. PMID: 24838444
We report the first general synthesis of boron-substituted monobenzofused 1,4-azaborines using ring-closing metathesis of an enamine-containing diene as a key synthetic strategy. As part of our investigations, we discovered that the B-C3 moiety in a 1,4-azaborine ca …
We report the first general synthesis of boron-substituted monobenzofused 1,4-azaborines using ring-closing metathesis of an enamine-contain …
Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis.
Lee JD, Kamaruzaman NA, Fung JN, Taylor SM, Turner BJ, Atkin JD, Woodruff TM, Noakes PG. Lee JD, et al. J Neuroinflammation. 2013 Sep 26;10:119. doi: 10.1186/1742-2094-10-119. J Neuroinflammation. 2013. PMID: 24067070 Free PMC article.
This study therefore aimed to determine the expression of complement components (C1qB, C4, factor B, C3/C3b, C5 and CD88) and regulators (CD55 and CD59a) in the lumbar spinal cord of hSOD1(G93A) mice during defined disease stages. ...Statistical differences between …
This study therefore aimed to determine the expression of complement components (C1qB, C4, factor B, C3/C3b, C5 and CD88) and …
Proteomic profiling following immunoaffinity capture of high-density lipoprotein: association of acute-phase proteins and complement factors with proinflammatory high-density lipoprotein in rheumatoid arthritis.
Watanabe J, Charles-Schoeman C, Miao Y, Elashoff D, Lee YY, Katselis G, Lee TD, Reddy ST. Watanabe J, et al. Arthritis Rheum. 2012 Jun;64(6):1828-37. doi: 10.1002/art.34363. Epub 2012 Jan 9. Arthritis Rheum. 2012. PMID: 22231638 Free PMC article.
These proteins included the acute-phase proteins apolipoprotein J, fibrinogen, haptoglobin, serum amyloid A, and complement factors (B, C3, and C9). The associations between proinflammatory HDL and 4 of the proteins were validated in a second RA cohort. ...
These proteins included the acute-phase proteins apolipoprotein J, fibrinogen, haptoglobin, serum amyloid A, and complement factors (B …
RhoA-ROCK-Myosin pathway regulates morphological plasticity of cultured olfactory ensheathing cells.
Huang ZH, Wang Y, Yuan XB, He C. Huang ZH, et al. Exp Cell Res. 2011 Dec 10;317(20):2823-34. doi: 10.1016/j.yexcr.2011.09.004. Epub 2011 Sep 17. Exp Cell Res. 2011. PMID: 21946234
Local disruption of these active RhoA distributions led to the morphological change from the flattened into process-bearing shape and promoted process outgrowth. Furthermore, RhoA pathway inhibitors, Toxin-B, C3, Y-27632 or over-expression of DN-RhoA blocked serum-i …
Local disruption of these active RhoA distributions led to the morphological change from the flattened into process-bearing shape and promot …
45 results