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Relations of diabetes intrusiveness and personal control to symptoms of depression among adults with diabetes.
Talbot F, Nouwen A, Gingras J, Bélanger A, Audet J. Talbot F, et al. Health Psychol. 1999 Sep;18(5):537-42. doi: 10.1037//0278-6133.18.5.537. Health Psychol. 1999. PMID: 10519470
The generalizability of a model linking illness characteristics to psychosocial well-being was tested in a cross-sectional study of 237 adults with type 2 diabetes. ...Assessment of an alternative model excluding personal control suggested that the extent to which d …
The generalizability of a model linking illness characteristics to psychosocial well-being was tested in a cross-sectional stu …
UGT2B23, a novel uridine diphosphate-glucuronosyltransferase enzyme expressed in steroid target tissues that conjugates androgen and estrogen metabolites.
Barbier O, Lévesque E, Bélanger A, Hum DW. Barbier O, et al. Endocrinology. 1999 Dec;140(12):5538-48. doi: 10.1210/endo.140.12.7192. Endocrinology. 1999. PMID: 10579317
Glucuronidation is widely accepted as a mechanism involved in the catabolism and elimination of steroid hormones from the body. ...A 1768-bp complementary DNA, encoding UGT2B23 was isolated from a monkey liver library. Stable expression of UGT2B23 in human HK …
Glucuronidation is widely accepted as a mechanism involved in the catabolism and elimination of steroid hormones from the body. ... …
31P NMR first spectral moment study of the partial magnetic orientation of phospholipid membranes.
Picard F, Paquet MJ, Levesque J, Bélanger A, Auger M. Picard F, et al. Biophys J. 1999 Aug;77(2):888-902. doi: 10.1016/S0006-3495(99)76940-7. Biophys J. 1999. PMID: 10423434 Free PMC article.
Structural data can be obtained on proteins inserted in magnetically oriented phospholipid membranes such as bicelles, which are most often made of a mixture of long and short chain phosphatidylcholine. ...From this first moment, an order parameter is defined that allows …
Structural data can be obtained on proteins inserted in magnetically oriented phospholipid membranes such as bicelles, which are most often …
Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine.
Bélanger AS, Caron P, Harvey M, Zimmerman PA, Mehlotra RK, Guillemette C. Bélanger AS, et al. Drug Metab Dispos. 2009 Sep;37(9):1793-6. doi: 10.1124/dmd.109.027706. Epub 2009 Jun 1. Drug Metab Dispos. 2009. PMID: 19487252 Free PMC article.
Moreover, assuming that concentrations of EFV achieved in plasma (C(max) = 12.9 microM) are in a range similar to its K(i) value, it was estimated that EFV could produce a theoretical 43% inhibition of AZT glucuronidation in vivo. We conclude that UGT2B7 has a
Moreover, assuming that concentrations of EFV achieved in plasma (C(max) = 12.9 microM) are in a range similar to its K(i) value, it …
Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells.
Bélanger AS, Tojcic J, Harvey M, Guillemette C. Bélanger AS, et al. BMC Mol Biol. 2010 Jan 22;11:9. doi: 10.1186/1471-2199-11-9. BMC Mol Biol. 2010. PMID: 20096102 Free PMC article.
BACKGROUND: UDP-glucuronosyltransferase 1A1 (UGT1A1) is a pivotal enzyme involved in metabolism of SN-38, the active metabolite of irinotecan commonly used to treat metastatic colorectal cancer. ...In agreement with the presence of CpG islands in the HNF1A promoter, treatm …
BACKGROUND: UDP-glucuronosyltransferase 1A1 (UGT1A1) is a pivotal enzyme involved in metabolism of SN-38, the active metabolite of ir …
EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium.
Labrie F, Labrie C, Bélanger A, Simard J, Gauthier S, Luu-The V, Mérand Y, Giguere V, Candas B, Luo S, Martel C, Singh SM, Fournier M, Coquet A, Richard V, Charbonneau R, Charpenet G, Tremblay A, Tremblay G, Cusan L, Veilleux R. Labrie F, et al. J Steroid Biochem Mol Biol. 1999 Apr-Jun;69(1-6):51-84. doi: 10.1016/s0960-0760(99)00065-5. J Steroid Biochem Mol Biol. 1999. PMID: 10418981 Review.
EM-800, the prodrug of EM-652, has been shown to prevent the development of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat, a well-recognized model of human breast cancer. It is of interest that the addition of dehydroepiandrosterone, a
EM-800, the prodrug of EM-652, has been shown to prevent the development of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinom …
Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology.
Labrie F, Bélanger A, Cusan L, Candas B. Labrie F, et al. J Clin Endocrinol Metab. 1997 Aug;82(8):2403-9. doi: 10.1210/jcem.82.8.4161. J Clin Endocrinol Metab. 1997. PMID: 9253308
This study analyzes in detail the serum concentration of the active androgens and estrogens, as well as a series of free and conjugated forms of their precursors and metabolites, after daily application for 2 weeks of 10 mL 20% dehydroepiandrosterone (DHEA) solution on the …
This study analyzes in detail the serum concentration of the active androgens and estrogens, as well as a series of free and conjugat …
Levels of eighteen non-conjugated and conjugated steroids in human breast cyst fluid: relationships with cyst type.
Bélanger A, Caron S, Labrie F, Naldoni C, Dogliotti L, Angeli A. Bélanger A, et al. Eur J Cancer. 1990 Mar;26(3):277-81. doi: 10.1016/0277-5379(90)90222-f. Eur J Cancer. 1990. PMID: 2141484
The present study investigates the levels of a large series of 18 non-conjugated or conjugated steroids in 71 samples of human breast cyst fluid (BCF) as divided into three groups corresponding to different electrolyte composition. ...A small or no difference was se …
The present study investigates the levels of a large series of 18 non-conjugated or conjugated steroids in 71 samples of human breast …
Androgen metabolites in bovine follicular fluid.
Prévost J, Bélanger A, Bernard C, Lambert RD. Prévost J, et al. Theriogenology. 1989 Mar;31(3):675-81. doi: 10.1016/0093-691x(89)90250-1. Theriogenology. 1989. PMID: 16726584
In the three cows treated with a hormone regimen to induce superovulation, the levels of progesterone and estradiol determined in 3 to 6 follicles per cow ranged from 65 to 448 ng/ml and 1.9 to 8.6 ng/ml, respectively while the concentrations of androstenedione and testost …
In the three cows treated with a hormone regimen to induce superovulation, the levels of progesterone and estradiol determined in 3 t …
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