B cells inhibit induction of T cell-dependent tumor immunity.
Nat Med. 1998.
PMID: 9585241
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B cells inhibit induction of T cell-dependent tumor immunity.
Nat Med. 1998 May;4(5):627-30. doi: 10.1038/nm0598-627.
Nat Med. 1998.
PMID: 9585241
Cytotoxic T lymphocyte (CTL) mediated tumor immunity against major histocompatibility antigen (MHC) class I-positive but class II-negative tumors often requires help from CD4+ T cells. ...These mice appear normal with regard to T cell …
Cytotoxic T lymphocyte (CTL) mediated tumor immunity against major histocompatibility antigen (MHC) class I-positive bu …
Vaccine-induced tumor-specific immunity despite severe B-cell depletion in mantle cell lymphoma.
Nat Med. 2005 Sep;11(9):986-91. doi: 10.1038/nm1290. Epub 2005 Aug 21.
Nat Med. 2005.
PMID: 16116429
Clinical Trial.
The role of B cells in T-cell priming is unclear, and the effects of B-cell depletion on immune responses to cancer vaccines are unknown. Although results from some mouse models suggest that B cells may inhibit induction of …
The role of B cells in T-cell priming is unclear, and the effects of B-cell depletion on immune responses to can …
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy.
J Exp Med. 1999 Nov 15;190(10):1535-40. doi: 10.1084/jem.190.10.1535.
J Exp Med. 1999.
PMID: 10562327
Free PMC article.
Inhibition of humoral immunity occurred only when anti-4-1BB mAb was given within 1 wk after immunization. ...However, B cells from the SRBC-immunized, anti-4-1BB-treated BALB/c mice, together with normal naive T cells, exhibited a …
Inhibition of humoral immunity occurred only when anti-4-1BB mAb was given within 1 wk after immunization. ...However, …
CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy in established tumors.
J Immunol. 2010 Jul 1;185(1):532-41. doi: 10.4049/jimmunol.0903624. Epub 2010 May 26.
J Immunol. 2010.
PMID: 20505139
Free article.
FcR mediated cross-linking of MD5-1 significantly inhibited the growth of MC38 colon adenocarcinomas through the induction of TRAIL-R-dependent tumor cell apoptosis. ...Overall, these data show that Ab-mediated targeting of DR5 triggers tumor cell apop …
FcR mediated cross-linking of MD5-1 significantly inhibited the growth of MC38 colon adenocarcinomas through the induction of …
The syngeneic T-T lymphocyte reaction (STTLR). II. Induction of primary T anti-T cell cytotoxic responses in vitro in T cell cultures stimulated with syngeneic self-reactive T cells.
J Mol Cell Immunol. 1986;2(6):345-57.
J Mol Cell Immunol. 1986.
PMID: 3509919
Resting T cells are also resistant to Dbl cells. Using LPS-induced splenic B cells from H-2 congenic mice, we map the anti-self specificity of uncloned and cloned anti-Lbd cells to the Kk + IAk regions of the MHC. ...These results suggested that the antigen r …
Resting T cells are also resistant to Dbl cells. Using LPS-induced splenic B cells from H-2 congenic mice, we map the a …
Inhibition of cytolytic T lymphocyte proliferation by autologous CD4+/CD25+ regulatory T cells in a colorectal carcinoma patient is mediated by transforming growth factor-beta.
Cancer Res. 2002 Sep 15;62(18):5267-72.
Cancer Res. 2002.
PMID: 12234995
The cytotoxic T-cell line and a clonal derivative specifically lysed the autologous tumor cells but not the B lymphocytes. ...The clone produced IFN-gamma and TNF-alpha. The regulatory CD4+/CD25+ T-cell line was tumor cell-depen …
The cytotoxic T-cell line and a clonal derivative specifically lysed the autologous tumor cells but not the B lympho …
The effects of T cell subpopulations and recombinant interleukin (IL)-2 on peripheral B cell function in patients with myasthenia gravis.
Hum Antibodies. 1997;8(2):90-4.
Hum Antibodies. 1997.
PMID: 9289393
The production of anti-AChR antibodies has been shown to be T cell dependent. To elucidate the mechanism(s) of anti-AChR antibody production in myasthenic patients, we studied the effects of regulatory T cells and/or IL-2 on the differentiation of AChR …
The production of anti-AChR antibodies has been shown to be T cell dependent. To elucidate the mechanism(s) of anti-ACh …
Cellular basis for the immune response to methylcholanthrene-induced tumors in mice. Heterogeneity of effector cells.
Int J Cancer. 1975 Mar 15;15(3):438-50. doi: 10.1002/ijc.2910150310.
Int J Cancer. 1975.
PMID: 1079792
Both phases were found to be T-cell-dependent in vivo. Thus, adult thymectomized, irradiated, bone-marrow-protected mice bearing H-1 tumor isografts showed impaired resistance to challenge with homologous (H-1) and heterologous (H-3) tumor cells …
Both phases were found to be T-cell-dependent in vivo. Thus, adult thymectomized, irradiated, bone-marrow-protected mic …
Recombinant interferon-beta blocks proliferation but enhances interleukin-10 secretion by activated human T-cells.
J Neuroimmunol. 1996 Jul;67(2):111-8. doi: 10.1016/0165-5728(96)00060-4.
J Neuroimmunol. 1996.
PMID: 8765333
To gain insight into the immunoregulatory properties of this cytokine, we analyzed effects of interferon-beta (IFN-beta) on T-cell functions in vitro. Interferon-beta inhibited T-cell proliferation, as well as T-cell-dependent immunoglobu …
To gain insight into the immunoregulatory properties of this cytokine, we analyzed effects of interferon-beta (IFN-beta) on T-cell fu …
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