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Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.
Wells DK, van Buuren MM, Dang KK, Hubbard-Lucey VM, Sheehan KCF, Campbell KM, Lamb A, Ward JP, Sidney J, Blazquez AB, Rech AJ, Zaretsky JM, Comin-Anduix B, Ng AHC, Chour W, Yu TV, Rizvi H, Chen JM, Manning P, Steiner GM, Doan XC; Tumor Neoantigen Selection Alliance; Merghoub T, Guinney J, Kolom A, Selinsky C, Ribas A, Hellmann MD, Hacohen N, Sette A, Heath JR, Bhardwaj N, Ramsdell F, Schreiber RD, Schumacher TN, Kvistborg P, Defranoux NA. Wells DK, et al. Cell. 2020 Oct 29;183(3):818-834.e13. doi: 10.1016/j.cell.2020.09.015. Epub 2020 Oct 9. Cell. 2020. PMID: 33038342 Free PMC article.
Structure Prediction and Mechanical Properties of Silicon Hexaboride on Ab Initio Level.
Škundrić T, Matović B, Zarubica A, Zagorac J, Tatarko P, Zagorac D. Škundrić T, et al. Materials (Basel). 2021 Dec 20;14(24):7887. doi: 10.3390/ma14247887. Materials (Basel). 2021. PMID: 34947479 Free PMC article.
Silicon borides represent very appealing industrial materials for research owing to their remarkable features, and, together with other boride and carbide-based materials, have very wide applications. Various Si-B phases have been investigated in the past, however a limite …
Silicon borides represent very appealing industrial materials for research owing to their remarkable features, and, together with other bori …
Emerging role of IL-16 in cytokine-mediated regulation of multiple sclerosis.
Skundric DS, Cruikshank WW, Montgomery PC, Lisak RP, Tse HY. Skundric DS, et al. Cytokine. 2015 Oct;75(2):234-48. doi: 10.1016/j.cyto.2015.01.005. Epub 2015 Feb 18. Cytokine. 2015. PMID: 25703787
Other major biological properties of IL-16 essential for the function of CD4(+) T cells include regulation of: T cell activation, CD25 expression, MHC class II expression, dendritic cell (DC)-T cell cooperation, B cell-T cell and T cell-T cell cooperation, inflammatory cyt …
Other major biological properties of IL-16 essential for the function of CD4(+) T cells include regulation of: T cell activation, CD25 expre …
Distinct immune regulation of the response to H-2b restricted epitope of MOG causes relapsing-remitting EAE in H-2b/s mice.
Skundric DS, Zakarian V, Dai R, Lisak RP, Tse HY, James J. Skundric DS, et al. J Neuroimmunol. 2003 Mar;136(1-2):34-45. doi: 10.1016/s0165-5728(03)00005-5. J Neuroimmunol. 2003. PMID: 12620641
To find immune mechanisms underlying relapse regulation, we developed a model of relapsing-remitting experimental autoimmune encephalomyelitis (EAE) in (B6xSJL) F1 (H-2(b/s)) mice by immunization with myelin oligodendrocyte glycoprotein peptide 35-55 (MOG(35-55)) and compa …
To find immune mechanisms underlying relapse regulation, we developed a model of relapsing-remitting experimental autoimmune encephalomyelit …
Role of IL-16 in CD4+ T cell-mediated regulation of relapsing multiple sclerosis.
Skundric DS, Cruikshank WW, Drulovic J. Skundric DS, et al. J Neuroinflammation. 2015 Apr 22;12:78. doi: 10.1186/s12974-015-0292-x. J Neuroinflammation. 2015. PMID: 25896927 Free PMC article.
Concomitant studies of RRMS lesions and corresponding MOG35-55-induced relapsing EAE in (B6 JL)F1 (H-2(b/s)) mice discovered similar roles of IL-16 in regulation of relapsing disease. In RRMS and EAE relapse, peak levels of IL-16 and active caspase-3 correlated with CD4( …
Concomitant studies of RRMS lesions and corresponding MOG35-55-induced relapsing EAE in (B6 JL)F1 (H-2(b/s)) mice discovered simila …
Anti-IL-16 therapy reduces CD4+ T-cell infiltration and improves paralysis and histopathology of relapsing EAE.
Skundric DS, Dai R, Zakarian VL, Bessert D, Skoff RP, Cruikshank WW, Kurjakovic Z. Skundric DS, et al. J Neurosci Res. 2005 Mar 1;79(5):680-93. doi: 10.1002/jnr.20377. J Neurosci Res. 2005. PMID: 15682385
IL-16 levels in the CNS correlated well with the extent of CD4+ T-cell and B-cell infiltration during acute and relapsing disease. Infiltrating CD4+ T cells, B cells, and to a lesser extent CD8+ T cells all contained IL-16 immunoreactivity. ...
IL-16 levels in the CNS correlated well with the extent of CD4+ T-cell and B-cell infiltration during acute and relapsing disease. In …
Experimental allergic encephalomyelitis. T cell trafficking to the central nervous system in a resistant Thy-1 congenic mouse strain.
Skundric DS, Huston K, Shaw M, Tse HY, Raine CS. Skundric DS, et al. Lab Invest. 1994 Nov;71(5):671-9. Lab Invest. 1994. PMID: 7526038
CONCLUSIONS: These results suggest that: (a) T lymphocytes from an EAE-resistant strain of mouse are capable of homing to the CNS; (b) T lymphocytes from an EAE-resistant strain express phenotypic characteristics, activation, memory, and cytokine profiles similar to infilt …
CONCLUSIONS: These results suggest that: (a) T lymphocytes from an EAE-resistant strain of mouse are capable of homing to the CNS; (b …