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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1980 1
1983 3
1985 1
1987 1
1988 3
1989 5
1990 8
1991 5
1992 2
1993 7
1994 9
1995 9
1996 20
1997 13
1998 12
1999 9
2000 17
2001 11
2002 19
2003 20
2004 20
2005 35
2006 59
2007 53
2008 65
2009 65
2010 99
2011 114
2012 127
2013 151
2014 183
2015 214
2016 250
2017 269
2018 332
2019 312
2020 334
2021 338
2022 388
2023 382
2024 324

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3,812 results

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Page 1
Targeting Cbl-b in cancer immunotherapy.
Augustin RC, Bao R, Luke JJ. Augustin RC, et al. Among authors: bao r. J Immunother Cancer. 2023 Feb;11(2):e006007. doi: 10.1136/jitc-2022-006007. J Immunother Cancer. 2023. PMID: 36750253 Free PMC article. Review.
The CD28 costimulatory pathway is necessary for antigen-specific T cell activation, though prior CD28 agonists did not translate successfully to clinic due to toxicity. Casitas B lymphoma-b (Cbl-b) is a downstream, master regulator of both CD28 and CTLA-4 sig …
The CD28 costimulatory pathway is necessary for antigen-specific T cell activation, though prior CD28 agonists did not translate successfull …
Salvianolic acid B inhibits atherosclerosis and TNF-alpha-induced inflammation by regulating NF-kappaB/NLRP3 signaling pathway.
Zhao Y, Shao C, Zhou H, Yu L, Bao Y, Mao Q, Yang J, Wan H. Zhao Y, et al. Among authors: bao y. Phytomedicine. 2023 Oct;119:155002. doi: 10.1016/j.phymed.2023.155002. Epub 2023 Aug 1. Phytomedicine. 2023. PMID: 37572566
The aim of this study was to investigate the protective effect of salvianolic acid B (Sal B) on AS and to explore the molecular mechanism of tumor necrosis factor-alpha (TNF-alpha)-induced damage in human umbilical vein endothelial cells (HUVECs). ...The pathologica …
The aim of this study was to investigate the protective effect of salvianolic acid B (Sal B) on AS and to explore the molecula …
Single-cell sequencing reveals the heterogeneity of B cells and tertiary lymphoid structures in muscle-invasive bladder cancer.
Yuan H, Mao X, Yan Y, Huang R, Zhang Q, Zeng Y, Bao M, Dai Y, Fang B, Mi J, Xie Y, Wang X, Zhang H, Mo Z, Yang R. Yuan H, et al. Among authors: bao m. J Transl Med. 2024 Jan 12;22(1):48. doi: 10.1186/s12967-024-04860-1. J Transl Med. 2024. PMID: 38216927 Free PMC article.
However, the function and mechanisms of tumor-infiltrating B cells and TLSs in MIBC need to be explored further. METHODS: We performed single-cell RNA sequencing analysis of 11,612 B cells and 55,392 T cells from 12 bladder cancer patients and found naive B c …
However, the function and mechanisms of tumor-infiltrating B cells and TLSs in MIBC need to be explored further. METHODS: We performe …
Single-Cell Profiling of Bone Marrow B Cells and Early B Cell Developmental Disorders Associated With Systemic Lupus Erythematosus.
Dong C, Guo Y, Chen Z, Li T, Ji J, Sun C, Li J, Cao H, Xia Y, Xue Z, Gu X, Liang Q, Zhao R, Fu T, Ma J, Jiang S, Wu C, Fu Q, Guo G, Bao Y, Guo H, Yang J, Xu M, Zhang X, Sheng Z, Gu Z. Dong C, et al. Among authors: bao y. Arthritis Rheumatol. 2024 Apr;76(4):599-613. doi: 10.1002/art.42750. Epub 2024 Jan 30. Arthritis Rheumatol. 2024. PMID: 37946666
OBJECTIVE: The peripheral B cell compartment is heavily disturbed in systemic lupus erythematosus (SLE), but whether B cells develop aberrantly in the bone marrow (BM) is largely unknown. METHODS: We performed single-cell RNA/B cell receptor (BCR) sequencing …
OBJECTIVE: The peripheral B cell compartment is heavily disturbed in systemic lupus erythematosus (SLE), but whether B cells d …
Exploring the dual role of B cells in solid tumors: implications for head and neck squamous cell carcinoma.
Bao J, Betzler AC, Hess J, Brunner C. Bao J, et al. Front Immunol. 2023 Oct 5;14:1233085. doi: 10.3389/fimmu.2023.1233085. eCollection 2023. Front Immunol. 2023. PMID: 37868967 Free PMC article. Review.
These cells are known as regulatory B (Breg) cells. Breg cells suppress immune responses by secreting a series of immunosuppressive cytokines, including IL-10, IL-35, TGF-beta, granzyme B, and adenosine or dampen effector TILs by intercellular contacts. ...However, …
These cells are known as regulatory B (Breg) cells. Breg cells suppress immune responses by secreting a series of immunosuppressive c …
B-Cell-Derived TGF-beta1 Inhibits Osteogenesis and Contributes to Bone Loss in Periodontitis.
Chen Y, Wang H, Ni Q, Wang T, Bao C, Geng Y, Lu Y, Cao Y, Li Y, Li L, Xu Y, Sun W. Chen Y, et al. Among authors: bao c. J Dent Res. 2023 Jul;102(7):767-776. doi: 10.1177/00220345231161005. Epub 2023 Apr 21. J Dent Res. 2023. PMID: 37082865
Besides, B-cell depletion therapy reduces the alveolar bone loss in a ligature-induced murine PD model. ...Lastly, CD19(+)CD27(+)CD38(-) memory B cells dominate the B-cell infiltrates in periodontal tissues from both patients with PD and patients with PD afte …
Besides, B-cell depletion therapy reduces the alveolar bone loss in a ligature-induced murine PD model. ...Lastly, CD19(+)CD27(+)CD38 …
Hepatic progenitor cell-originated ductular reaction facilitates liver fibrosis through activation of hedgehog signaling.
Hu Y, Bao X, Zhang Z, Chen L, Liang Y, Qu Y, Zhou Q, Zhou X, Fang J, Xiao Z, Fu Y, Yang H, Liu W, Lv Y, Cao H, Chen G, Ping J, Zhang H, Mu Y, Liu C, Lin CP, Wu J, Liu P, Chen J. Hu Y, et al. Among authors: bao x. Theranostics. 2024 Mar 25;14(6):2379-2395. doi: 10.7150/thno.91572. eCollection 2024. Theranostics. 2024. PMID: 38646644 Free PMC article.
Epigenetic Control of B Cell Development and B-Cell-Related Immune Disorders.
Bao Y, Cao X. Bao Y, et al. Clin Rev Allergy Immunol. 2016 Jun;50(3):301-11. doi: 10.1007/s12016-015-8494-7. Clin Rev Allergy Immunol. 2016. PMID: 26066671 Review.
Better understanding of the epigenetic mechanisms for regulating B cell development and involving B cell abnormal differentiation and function will shed light on the design of new therapeutic approaches to B-cell-related diseases, and potential candidates of …
Better understanding of the epigenetic mechanisms for regulating B cell development and involving B cell abnormal differentiat …
Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the "Smart" exosome nanoparticle therapy.
Wu X, Ban C, Deng W, Bao X, Tang N, Wu Y, Deng Z, Xiong J, Zhao Q. Wu X, et al. Among authors: bao x. Mol Cancer. 2024 Jul 15;23(1):144. doi: 10.1186/s12943-024-02057-0. Mol Cancer. 2024. PMID: 39004737 Free PMC article.
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) represents a prevalent malignant tumor, with approximately 40% of patients encountering treatment challenges or relapse attributed to rituximab resistance, primarily due to diminished or absent CD20 expression. ...
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) represents a prevalent malignant tumor, with approximately 40% of patients encounte …
Mature tertiary lymphoid structures: important contributors to anti-tumor immune efficacy.
Bao X, Lin X, Xie M, Yao J, Song J, Ma X, Zhang X, Zhang Y, Liu Y, Han W, Liang Y, Hu H, Xu L, Xue X. Bao X, et al. Front Immunol. 2024 Jul 4;15:1413067. doi: 10.3389/fimmu.2024.1413067. eCollection 2024. Front Immunol. 2024. PMID: 39026670 Free PMC article. Review.
Mature TLS, characterized by germinal centers and areas of T-cell and B-cell aggregation, are considered primary locations for activating and maintaining both humoral and cellular anti-tumor immune effects. ...
Mature TLS, characterized by germinal centers and areas of T-cell and B-cell aggregation, are considered primary locations for activa …
3,812 results