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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1953 3
1955 1
1957 2
1959 2
1960 2
1962 1
1963 1
1964 2
1965 3
1967 4
1969 1
1970 1
1971 3
1972 3
1973 4
1974 5
1975 14
1976 14
1977 7
1978 7
1979 11
1980 13
1981 9
1982 17
1983 9
1984 14
1985 16
1986 29
1987 24
1988 24
1989 25
1990 27
1991 24
1992 34
1993 36
1994 30
1995 51
1996 39
1997 29
1998 36
1999 24
2000 42
2001 37
2002 46
2003 27
2004 27
2005 36
2006 50
2007 57
2008 45
2009 31
2010 43
2011 44
2012 68
2013 65
2014 67
2015 112
2016 121
2017 107
2018 102
2019 82
2020 79
2021 89
2022 93
2023 101
2024 112
2025 5

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2,146 results

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Page 1
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Among authors: shapiro vs. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.
B cells reach the meninges from the calvaria through specialized vascular connections. This calvarial-meningeal path of B cell development may provide the CNS with a constant supply of B cells educated by CNS antigens. ...
B cells reach the meninges from the calvaria through specialized vascular connections. This calvarial-meningeal path of B cell …
Apolipoproteins in vascular biology and atherosclerotic disease.
Mehta A, Shapiro MD. Mehta A, et al. Among authors: shapiro md. Nat Rev Cardiol. 2022 Mar;19(3):168-179. doi: 10.1038/s41569-021-00613-5. Epub 2021 Oct 8. Nat Rev Cardiol. 2022. PMID: 34625741 Review.
Clinically important apolipoproteins related to lipid metabolism and atherogenesis include apolipoprotein B-100, apolipoprotein B-48, apolipoprotein A-I, apolipoprotein C-II, apolipoprotein C-III, apolipoprotein E and apolipoprotein(a). Apolipoprotein B-100 i …
Clinically important apolipoproteins related to lipid metabolism and atherogenesis include apolipoprotein B-100, apolipoprotein B …
Concizumab: a novel anti-TFPI therapeutic for hemophilia.
Shapiro AD. Shapiro AD. Blood Adv. 2021 Jan 12;5(1):279. doi: 10.1182/bloodadvances.2019001140. Blood Adv. 2021. PMID: 33570646 Free PMC article.
Results from 2 phase 2 trials in patients with hemophilia A or B with and without inhibitors demonstrated that concizumab had a favorable safety profile, with no deaths, no thromboembolic events, and no adverse events leading to withdrawal. ...In the ongoing concizumab pha …
Results from 2 phase 2 trials in patients with hemophilia A or B with and without inhibitors demonstrated that concizumab had a favor …
Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B.
Chowdary P, Shapiro S, Makris M, Evans G, Boyce S, Talks K, Dolan G, Reiss U, Phillips M, Riddell A, Peralta MR, Quaye M, Patch DW, Tuddenham E, Dane A, Watissée M, Long A, Nathwani A. Chowdary P, et al. Among authors: shapiro s. N Engl J Med. 2022 Jul 21;387(3):237-247. doi: 10.1056/NEJMoa2119913. N Engl J Med. 2022. PMID: 35857660 Free article. Clinical Trial.
BACKGROUND: FLT180a (verbrinacogene setparvovec) is a liver-directed adeno-associated virus (AAV) gene therapy that uses a synthetic capsid and a gain-of-function protein to normalize factor IX levels in patients with hemophilia B. METHODS: In this multicenter, open-label, …
BACKGROUND: FLT180a (verbrinacogene setparvovec) is a liver-directed adeno-associated virus (AAV) gene therapy that uses a synthetic capsid …
Parametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool: the Vitiligo Area Scoring Index.
Hamzavi I, Jain H, McLean D, Shapiro J, Zeng H, Lui H. Hamzavi I, et al. Among authors: shapiro j. Arch Dermatol. 2004 Jun;140(6):677-83. doi: 10.1001/archderm.140.6.677. Arch Dermatol. 2004. PMID: 15210457 Clinical Trial.
OBJECTIVE: To develop and apply a simple clinical tool, the Vitiligo Area Scoring Index (VASI), to model the response of vitiligo to narrowband UV-B (NB-UV-B) phototherapy using parametric tests. DESIGN: Prospective, randomized, controlled, bilateral left-right comp …
OBJECTIVE: To develop and apply a simple clinical tool, the Vitiligo Area Scoring Index (VASI), to model the response of vitiligo to narrowb …
Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B.
Cuker A, Kavakli K, Frenzel L, Wang JD, Astermark J, Cerqueira MH, Iorio A, Katsarou-Fasouli O, Klamroth R, Shapiro AD, Hermans C, Ishiguro A, Leavitt AD, Oldenburg JB, Ozelo MC, Teitel J, Biondo F, Fang A, Fuiman J, McKay J, Sun P, Rasko JEJ, Rupon J; BENEGENE-2 Trial Investigators. Cuker A, et al. Among authors: shapiro ad. N Engl J Med. 2024 Sep 26;391(12):1108-1118. doi: 10.1056/NEJMoa2302982. N Engl J Med. 2024. PMID: 39321362 Clinical Trial.
BACKGROUND: Fidanacogene elaparvovec, an adeno-associated virus (AAV) gene-therapy vector for hemophilia B containing a high-activity human factor IX variant (FIX-R338L/FIX-Padua), was associated with sustained factor IX activity in a phase 1-2a study. ...Men 18 to 65 year …
BACKGROUND: Fidanacogene elaparvovec, an adeno-associated virus (AAV) gene-therapy vector for hemophilia B containing a high-activity …
Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease.
Shapiro MD, Fazio S. Shapiro MD, et al. F1000Res. 2017 Feb 13;6:134. doi: 10.12688/f1000research.9845.1. eCollection 2017. F1000Res. 2017. PMID: 28299190 Free PMC article. Review.
Cholesterol-rich, apolipoprotein B (apoB)-containing lipoproteins are now widely accepted as the most important causal agents of atherosclerotic cardiovascular disease. ...
Cholesterol-rich, apolipoprotein B (apoB)-containing lipoproteins are now widely accepted as the most important causal agents of athe …
Howard B. Eichenbaum (1947-2017).
Cohen NJ, Shapiro M. Cohen NJ, et al. Among authors: shapiro m. Am Psychol. 2018 Apr;73(3):290. doi: 10.1037/amp0000203. Am Psychol. 2018. PMID: 29648848
Presents an obituary of Howard B. Eichenbaum (1947-2017). Eichenbaum, a world leader in the study of memory and the brain, died in Boston, Massachusetts, on July 21, 2017, at age 69, following recent spine surgery. ...
Presents an obituary of Howard B. Eichenbaum (1947-2017). Eichenbaum, a world leader in the study of memory and the brain, died in Bo …
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Zhu X, Wu Y, Li Y, Zhou X, Watzlawik JO, Chen YM, Raybuck AL, Billadeau DD, Shapiro VS, Springer W, Sun J, Boothby MR, Zeng H. Zhu X, et al. Among authors: shapiro vs. Nat Commun. 2024 Nov 23;15(1):10163. doi: 10.1038/s41467-024-54344-5. Nat Commun. 2024. PMID: 39580479 Free PMC article.
However, the contribution of these factors to humoral immunity remains undefined. Here, we show that B cell-intrinsic Rag-GTPases are critical for the development and activation of B cells. ...Deletion of RagA/RagB in GC B cells leads to abnormal dark zone (D …
However, the contribution of these factors to humoral immunity remains undefined. Here, we show that B cell-intrinsic Rag-GTPases are …
Epidemiology of hepatitis B.
Shapiro CN. Shapiro CN. Pediatr Infect Dis J. 1993 May;12(5):433-7. doi: 10.1097/00006454-199305000-00036. Pediatr Infect Dis J. 1993. PMID: 8392167 Review.
Because chronic hepatitis B virus infection is associated with long term consequences of cirrhosis and primary hepatocellular carcinoma, prevention of chronic infection is the most important reason for vaccination against hepatitis B. Routine infant immunization is …
Because chronic hepatitis B virus infection is associated with long term consequences of cirrhosis and primary hepatocellular carcino …
2,146 results