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Page 1
Branched Chain Amino Acids.
Neinast M, Murashige D, Arany Z. Neinast M, et al. Annu Rev Physiol. 2019 Feb 10;81:139-164. doi: 10.1146/annurev-physiol-020518-114455. Epub 2018 Nov 28. Annu Rev Physiol. 2019. PMID: 30485760 Free PMC article. Review.
Branched chain amino acids (BCAAs) are building blocks for all life-forms. We review here the fundamentals of BCAA metabolism in mammalian physiology. ...Inborn errors of metabolism highlight the importance of organismal regulation of BCAA …
Branched chain amino acids (BCAAs) are building blocks for all life-forms. We review here the fundamentals of …
Branched-Chain Amino Acids in Liver Diseases: Complexity and Controversy.
Zhang Y, Zhan L, Zhang L, Shi Q, Li L. Zhang Y, et al. Nutrients. 2024 Jun 14;16(12):1875. doi: 10.3390/nu16121875. Nutrients. 2024. PMID: 38931228 Free PMC article. Review.
Branched-chain amino acids (BCAAs), as essential amino acids, engage in various physiological processes, such as protein synthesis, energy supply, and cellular signaling. The liver is a crucial site for BCAA metabolism, linking the …
Branched-chain amino acids (BCAAs), as essential amino acids, engage in various physiological proc …
Branched-Chain Amino Acids.
Yamamoto K, Tsuchisaka A, Yukawa H. Yamamoto K, et al. Adv Biochem Eng Biotechnol. 2017;159:103-128. doi: 10.1007/10_2016_28. Adv Biochem Eng Biotechnol. 2017. PMID: 27872960 Review.
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that cannot be synthesized in higher organisms and are important nutrition for humans as well as livestock. ...Here, we describe th …
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino a …
Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street.
White PJ, McGarrah RW, Herman MA, Bain JR, Shah SH, Newgard CB. White PJ, et al. Mol Metab. 2021 Oct;52:101261. doi: 10.1016/j.molmet.2021.101261. Epub 2021 May 24. Mol Metab. 2021. PMID: 34044180 Free PMC article. Review.
BACKGROUND: A strong association of obesity and insulin resistance with increased circulating levels of branched-chain and aromatic amino acids and decreased glycine levels has been recognized in human subjects for decades. SCOPE OF REVIEW: More recent …
BACKGROUND: A strong association of obesity and insulin resistance with increased circulating levels of branched-chain and aro …
Isolated Leucine and Branched-Chain Amino Acid Supplementation for Enhancing Muscular Strength and Hypertrophy: A Narrative Review.
Plotkin DL, Delcastillo K, Van Every DW, Tipton KD, Aragon AA, Schoenfeld BJ. Plotkin DL, et al. Int J Sport Nutr Exerc Metab. 2021 May 1;31(3):292-301. doi: 10.1123/ijsnem.2020-0356. Epub 2021 Mar 18. Int J Sport Nutr Exerc Metab. 2021. PMID: 33741748 Free article. Review.
Branched-chain amino acids (BCAA) are one of the most popular sports supplements, marketed under the premise that they enhance muscular adaptations. Despite their prevalent consumption among athletes and the general public, the efficacy of BC …
Branched-chain amino acids (BCAA) are one of the most popular sports supplements, marketed under the prem …
Branched chain amino acids exacerbate myocardial ischemia/reperfusion vulnerability via enhancing GCN2/ATF6/PPAR-alpha pathway-dependent fatty acid oxidation.
Li Y, Xiong Z, Yan W, Gao E, Cheng H, Wu G, Liu Y, Zhang L, Li C, Wang S, Fan M, Zhao H, Zhang F, Tao L. Li Y, et al. Theranostics. 2020 Apr 27;10(12):5623-5640. doi: 10.7150/thno.44836. eCollection 2020. Theranostics. 2020. PMID: 32373236 Free PMC article.
Rationale: Myocardial vulnerability to ischemia/reperfusion (I/R) injury is strictly regulated by energy substrate metabolism. Branched chain amino acids (BCAA), consisting of valine, leucine and isoleucine, are a group of essential amino …
Rationale: Myocardial vulnerability to ischemia/reperfusion (I/R) injury is strictly regulated by energy substrate metabolism. Branched …
Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids.
Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z. Neinast MD, et al. Cell Metab. 2019 Feb 5;29(2):417-429.e4. doi: 10.1016/j.cmet.2018.10.013. Epub 2018 Nov 15. Cell Metab. 2019. PMID: 30449684 Free PMC article.
Elevations in branched-chain amino acids (BCAAs) associate with numerous systemic diseases, including cancer, diabetes, and heart failure. ...Genetic and pharmacologic suppression of branched-chain alpha-ketoacid dehydrogenase kinase, a c …
Elevations in branched-chain amino acids (BCAAs) associate with numerous systemic diseases, including cancer, di …
Branched-chain amino acids deficiency promotes diabetic cardiomyopathy by activating autophagy of cardiac fibroblasts.
Zhou ZY, Song K, Liu ZY, Ke YF, Shi Y, Cai K, Zhao R, Sun X, Tao H, Zhao JY. Zhou ZY, et al. Theranostics. 2024 Oct 28;14(19):7333-7348. doi: 10.7150/thno.102708. eCollection 2024. Theranostics. 2024. PMID: 39659577 Free PMC article.
In high-fat diet/low-dose streptozotocin-induced T2D and leptin receptor-deficient diabetic mouse models, we investigated the effect of altering branched-chain amino acids (BCAAs) levels on DCM. Results: We discovered that the levels of plasma BCAAs ar …
In high-fat diet/low-dose streptozotocin-induced T2D and leptin receptor-deficient diabetic mouse models, we investigated the effect of alte …
The effects of branched-chain amino acids on muscle protein synthesis, muscle protein breakdown and associated molecular signalling responses in humans: an update.
Kaspy MS, Hannaian SJ, Bell ZW, Churchward-Venne TA. Kaspy MS, et al. Nutr Res Rev. 2024 Dec;37(2):273-286. doi: 10.1017/S0954422423000197. Epub 2023 Sep 8. Nutr Res Rev. 2024. PMID: 37681443 Review.
Branched-chain amino acids (BCAA: leucine, isoleucine and valine) are three of the nine indispensable amino acids, and are frequently consumed as a dietary supplement by athletes and recreationally active individuals alike. ...Howe …
Branched-chain amino acids (BCAA: leucine, isoleucine and valine) are three of the nine indispensable …
Circulating Branched Chain Amino Acids and Cardiometabolic Disease.
Fine KS, Wilkins JT, Sawicki KT. Fine KS, et al. J Am Heart Assoc. 2024 Apr 2;13(7):e031617. doi: 10.1161/JAHA.123.031617. Epub 2024 Mar 18. J Am Heart Assoc. 2024. PMID: 38497460 Free PMC article. Review.
Branched chain amino acids (BCAAs) are essential for protein homeostasis, energy balance, and signaling pathways. ...In this review, we provide a detailed overview of BCAA metabolism, focus on molecular mechanisms linking disrupted BCAA h …
Branched chain amino acids (BCAAs) are essential for protein homeostasis, energy balance, and signaling pathways …
3,133 results