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Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
J Am Acad Orthop Surg Glob Res Rev. 2026 Jan 2;10(1):e25.00236. doi: 10.5435/JAAOSGlobal-D-25-00236. eCollection 2026 Jan 1.
J Am Acad Orthop Surg Glob Res Rev. 2026.
PMID: 41490200
Free PMC article.
Review.
By acting on key pathways such as PI3K/Akt, mTOR, MAPK, TGF-beta, and AMPK, peptides exert influence over tissue regeneration, inflammation resolution, and neuromuscular recovery. Wound-healing peptides such as BPC-157, TB-500, and GHK-Cu promote angio …
By acting on key pathways such as PI3K/Akt, mTOR, MAPK, TGF-beta, and AMPK, peptides exert influence over tissue regeneration, inflammation …
Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.
Mayfield CK, Bolia IK, Feingold CL, Lin EH, Liu JN, Rick Hatch GF, Gamradt SC, Weber AE.
Mayfield CK, et al.
Am J Sports Med. 2026 Jan;54(1):223-229. doi: 10.1177/03635465251357593. Epub 2026 Jan 1.
Am J Sports Med. 2026.
PMID: 41476424
Review.
METHODS: A comprehensive literature search was conducted using PubMed to identify biochemical and clinical studies on the most popular types of injectable peptide therapy. Key peptides evaluated included BPC-157, TB-4, TB-500, CJC-1295 + ipamorelin, te …
METHODS: A comprehensive literature search was conducted using PubMed to identify biochemical and clinical studies on the most popular types …
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