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Year Number of Results
1991 1
1994 1
1995 3
1996 1
1997 1
1998 5
1999 5
2000 6
2001 15
2002 11
2003 11
2004 11
2005 18
2006 14
2007 13
2008 16
2009 15
2010 9
2011 14
2012 17
2013 14
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2015 28
2016 19
2017 15
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2024 9

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363 results

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Page 1
BUB3, beyond the Simple Role of Partner.
Silva PMA, Bousbaa H. Silva PMA, et al. Pharmaceutics. 2022 May 18;14(5):1084. doi: 10.3390/pharmaceutics14051084. Pharmaceutics. 2022. PMID: 35631670 Free PMC article. Review.
Besides its role in SAC signaling, BUB3 regulates chromosome attachment to the spindle microtubules. It is also involved in telomere replication and maintenance. Deficiency of the BUB3 gene has been closely linked to premature aging. Upregulation of the BUB3
Besides its role in SAC signaling, BUB3 regulates chromosome attachment to the spindle microtubules. It is also involved in telomere …
Research progress of Bub3 gene in malignant tumors.
Wang C, Cheng D, Pan C, Wang C, Nie Z. Wang C, et al. Cell Biol Int. 2022 May;46(5):673-682. doi: 10.1002/cbin.11740. Epub 2022 Feb 24. Cell Biol Int. 2022. PMID: 34882895 Free PMC article. Review.
Abnormal expression of Bub3 results in mitotic defects, defective spindle gate function, chromosomal instability and the development of aneuploidy cells. ...In this review, we summarize the expression and clinical significance of Bub3 in a variety of tumors and sugg …
Abnormal expression of Bub3 results in mitotic defects, defective spindle gate function, chromosomal instability and the development …
Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila.
Zhang Q, Zheng H, Yang S, Feng T, Jie M, Chen H, Jiang H. Zhang Q, et al. Cell Rep. 2023 Apr 25;42(4):112343. doi: 10.1016/j.celrep.2023.112343. Epub 2023 Apr 5. Cell Rep. 2023. PMID: 37027296 Free article.
Bidirectional deviations of the Bub1 or Bub3 level affect the consumption of triacylglycerol (TAG) of fat bodies and the survival rate of adult flies under starving. Moreover, Bub1 and Bub3 work together to attenuate lipid degradation via macrolipophagy upon fasting …
Bidirectional deviations of the Bub1 or Bub3 level affect the consumption of triacylglycerol (TAG) of fat bodies and the survival rat …
Bub3 activation and inhibition of the APC/C.
Yang Y, Lacefield S. Yang Y, et al. Cell Cycle. 2016;15(1):1-2. doi: 10.1080/15384101.2015.1106746. Cell Cycle. 2016. PMID: 26771710 Free PMC article. No abstract available.
Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival.
Kudryashova TV, Dabral S, Nayakanti S, Ray A, Goncharov DA, Avolio T, Shen Y, Rode A, Pena A, Jiang L, Lin D, Baust J, Bachman TN, Graumann J, Ruppert C, Guenther A, Schmoranzer M, Grobs Y, Eve Lemay S, Tremblay E, Breuils-Bonnet S, Boucherat O, Mora AL, DeLisser H, Zhao J, Zhao Y, Bonnet S, Seeger W, Pullamsetti SS, Goncharova EA. Kudryashova TV, et al. Circ Res. 2022 Mar 4;130(5):760-778. doi: 10.1161/CIRCRESAHA.121.319100. Epub 2022 Feb 7. Circ Res. 2022. PMID: 35124974 Free PMC article.
In PAH pulmonary arterial vascular smooth muscle cells, MST1/2 acted via forming a disease-specific interaction with BUB3 and supported ECM (extracellular matrix)- and USP10-dependent BUB3 accumulation, upregulation of Akt-mTORC1, cell proliferation, and survival. . …
In PAH pulmonary arterial vascular smooth muscle cells, MST1/2 acted via forming a disease-specific interaction with BUB3 and support …
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3.
Perlee S, Kikuchi S, Nakadai T, Masuda T, Ohtsuki S, Matsumoto M, Rahmutulla B, Fukuyo M, Cifani P, Kentsis A, Roeder RG, Kaneda A, Hoshii T. Perlee S, et al. EMBO Rep. 2023 Oct 9;24(10):e57108. doi: 10.15252/embr.202357108. Epub 2023 Aug 3. EMBO Rep. 2023. PMID: 37535603 Free article.
Our screen for FLOS domain-binding partners reveals that the SETD1A FLOS domain binds mitosis-associated proteins BuGZ/BUB3. Inhibition of both cyclin K and BuGZ/BUB3-binding motifs in SETD1A shows synergistic antileukemic effects. BuGZ/BUB3 localize to SETD1 …
Our screen for FLOS domain-binding partners reveals that the SETD1A FLOS domain binds mitosis-associated proteins BuGZ/BUB3. Inhibiti …
The BUB3-BUB1 Complex Promotes Telomere DNA Replication.
Li F, Kim H, Ji Z, Zhang T, Chen B, Ge Y, Hu Y, Feng X, Han X, Xu H, Zhang Y, Yu H, Liu D, Ma W, Songyang Z. Li F, et al. Mol Cell. 2018 May 3;70(3):395-407.e4. doi: 10.1016/j.molcel.2018.03.032. Mol Cell. 2018. PMID: 29727616 Free PMC article.
Loss of the BUB3-BUB1 complex results in telomere replication defects, including fragile and shortened telomeres. We also demonstrate that the telomere-binding ability of BUB3 and kinase activity of BUB1 are indispensable to BUB3-BUB1 function at telomeres. . …
Loss of the BUB3-BUB1 complex results in telomere replication defects, including fragile and shortened telomeres. We also demonstrate …
Bub3 promotes Cdc20-dependent activation of the APC/C in S. cerevisiae.
Yang Y, Tsuchiya D, Lacefield S. Yang Y, et al. J Cell Biol. 2015 May 25;209(4):519-27. doi: 10.1083/jcb.201412036. Epub 2015 May 18. J Cell Biol. 2015. PMID: 25987604 Free PMC article.
In this paper, we demonstrate that Bub3 has an unexpected role promoting metaphase progression in budding yeast. ...Although Bub1 binds Bub3 at the kinetochore, bub1delta cells did not have compromised APC/C and Cdc20 binding. ...
In this paper, we demonstrate that Bub3 has an unexpected role promoting metaphase progression in budding yeast. ...Although Bub1 bin …
Spindly and Bub3 expression in oral cancer: Prognostic and therapeutic implications.
Silva PMA, Delgado ML, Ribeiro N, Florindo C, Tavares ÁA, Ribeiro D, Lopes C, do Amaral B, Bousbaa H, Monteiro LS. Silva PMA, et al. Oral Dis. 2019 Jul;25(5):1291-1301. doi: 10.1111/odi.13089. Epub 2019 Apr 4. Oral Dis. 2019. PMID: 30866167
RESULTS: Overexpression of Bub3 and Spindly was detected in OSCC patients. High expression of Spindly, Bub3, or both was an independent prognostic indicator for cancer-specific survival and was associated with increased cellular proliferation. Accordingly, Bub3
RESULTS: Overexpression of Bub3 and Spindly was detected in OSCC patients. High expression of Spindly, Bub3, or both was an in …
Analysis of Bub3 and Nup75 in the Drosophila male germline lineage.
Yildirim K, van Nierop Y Sanchez P, Lohmann I. Yildirim K, et al. Cells Dev. 2023 Sep;175:203863. doi: 10.1016/j.cdev.2023.203863. Epub 2023 Jun 5. Cells Dev. 2023. PMID: 37286104 Free article.
To improve our understanding of these processes, we analysed the function of the mitotic checkpoint complex (MCC) component Bub3 and the nucleoporin Nup75, a component of the nuclear pore complex realizing the transport of signalling effector molecules to the nucleus, in t …
To improve our understanding of these processes, we analysed the function of the mitotic checkpoint complex (MCC) component Bub3 and …
363 results