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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1994 1
1995 3
1996 1
1997 1
1998 5
1999 5
2000 6
2001 15
2002 11
2003 11
2004 11
2005 18
2006 14
2007 13
2008 16
2009 15
2010 9
2011 14
2012 17
2013 14
2014 26
2015 28
2016 19
2017 15
2018 16
2019 10
2020 12
2021 13
2022 18
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335 results
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Page 1
BUB3, beyond the Simple Role of Partner.
Silva PMA, Bousbaa H. Silva PMA, et al. Pharmaceutics. 2022 May 18;14(5):1084. doi: 10.3390/pharmaceutics14051084. Pharmaceutics. 2022. PMID: 35631670 Free PMC article. Review.
Besides its role in SAC signaling, BUB3 regulates chromosome attachment to the spindle microtubules. It is also involved in telomere replication and maintenance. Deficiency of the BUB3 gene has been closely linked to premature aging. Upregulation of the BUB3
Besides its role in SAC signaling, BUB3 regulates chromosome attachment to the spindle microtubules. It is also involved in telomere …
Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer.
Park SH, Fong KW, Kim J, Wang F, Lu X, Lee Y, Brea LT, Wadosky K, Guo C, Abdulkadir SA, Crispino JD, Fang D, Ntziachristos P, Liu X, Li X, Wan Y, Goodrich DW, Zhao JC, Yu J. Park SH, et al. Sci Adv. 2021 Apr 7;7(15):eabe2261. doi: 10.1126/sciadv.abe2261. Print 2021 Apr. Sci Adv. 2021. PMID: 33827814 Free PMC article.
Here, we report FOXA1 as a nonhistone substrate of enhancer of zeste homolog 2 (EZH2), which methylates FOXA1 at lysine-295. This methylation is recognized by WD40 repeat protein BUB3, which subsequently recruits ubiquitin-specific protease 7 (USP7) to remove ubiquitinatio …
Here, we report FOXA1 as a nonhistone substrate of enhancer of zeste homolog 2 (EZH2), which methylates FOXA1 at lysine-295. This methylatio …
Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival.
Kudryashova TV, Dabral S, Nayakanti S, Ray A, Goncharov DA, Avolio T, Shen Y, Rode A, Pena A, Jiang L, Lin D, Baust J, Bachman TN, Graumann J, Ruppert C, Guenther A, Schmoranzer M, Grobs Y, Eve Lemay S, Tremblay E, Breuils-Bonnet S, Boucherat O, Mora AL, DeLisser H, Zhao J, Zhao Y, Bonnet S, Seeger W, Pullamsetti SS, Goncharova EA. Kudryashova TV, et al. Circ Res. 2022 Mar 4;130(5):760-778. doi: 10.1161/CIRCRESAHA.121.319100. Epub 2022 Feb 7. Circ Res. 2022. PMID: 35124974
In PAH pulmonary arterial vascular smooth muscle cells, MST1/2 acted via forming a disease-specific interaction with BUB3 and supported ECM (extracellular matrix)- and USP10-dependent BUB3 accumulation, upregulation of Akt-mTORC1, cell proliferation, and survival. . …
In PAH pulmonary arterial vascular smooth muscle cells, MST1/2 acted via forming a disease-specific interaction with BUB3 and support …
Research progress of Bub3 gene in malignant tumors.
Wang C, Cheng D, Pan C, Wang C, Nie Z. Wang C, et al. Cell Biol Int. 2022 May;46(5):673-682. doi: 10.1002/cbin.11740. Epub 2022 Feb 24. Cell Biol Int. 2022. PMID: 34882895 Free PMC article. Review.
Abnormal expression of Bub3 results in mitotic defects, defective spindle gate function, chromosomal instability and the development of aneuploidy cells. ...In this review, we summarize the expression and clinical significance of Bub3 in a variety of tumors and sugg …
Abnormal expression of Bub3 results in mitotic defects, defective spindle gate function, chromosomal instability and the development …
The BUB3-BUB1 Complex Promotes Telomere DNA Replication.
Li F, Kim H, Ji Z, Zhang T, Chen B, Ge Y, Hu Y, Feng X, Han X, Xu H, Zhang Y, Yu H, Liu D, Ma W, Songyang Z. Li F, et al. Mol Cell. 2018 May 3;70(3):395-407.e4. doi: 10.1016/j.molcel.2018.03.032. Mol Cell. 2018. PMID: 29727616 Free PMC article.
Loss of the BUB3-BUB1 complex results in telomere replication defects, including fragile and shortened telomeres. We also demonstrate that the telomere-binding ability of BUB3 and kinase activity of BUB1 are indispensable to BUB3-BUB1 function at telomeres. . …
Loss of the BUB3-BUB1 complex results in telomere replication defects, including fragile and shortened telomeres. We also demonstrate …
Bub3 activation and inhibition of the APC/C.
Yang Y, Lacefield S. Yang Y, et al. Cell Cycle. 2016;15(1):1-2. doi: 10.1080/15384101.2015.1106746. Cell Cycle. 2016. PMID: 26771710 Free PMC article. No abstract available.
Role of the BUB3 protein in phragmoplast microtubule reorganization during cytokinesis.
Zhang H, Deng X, Sun B, Lee Van S, Kang Z, Lin H, Lee YJ, Liu B. Zhang H, et al. Nat Plants. 2018 Jul;4(7):485-494. doi: 10.1038/s41477-018-0192-z. Epub 2018 Jul 2. Nat Plants. 2018. PMID: 29967519
BUB3;1 and BUB3;2 interacted with the carboxy-terminal segment of MAP65-3 (but not MAP65-1), which harbours its microtubule-binding domain for its post-mitotic localization. Reciprocally, BUB3;1 and BUB3;2 also regulated MAP65-3 localization in the phr
BUB3;1 and BUB3;2 interacted with the carboxy-terminal segment of MAP65-3 (but not MAP65-1), which harbours its microtubule-bi
Spindly and Bub3 expression in oral cancer: Prognostic and therapeutic implications.
Silva PMA, Delgado ML, Ribeiro N, Florindo C, Tavares ÁA, Ribeiro D, Lopes C, do Amaral B, Bousbaa H, Monteiro LS. Silva PMA, et al. Oral Dis. 2019 Jul;25(5):1291-1301. doi: 10.1111/odi.13089. Epub 2019 Apr 4. Oral Dis. 2019. PMID: 30866167
RESULTS: Overexpression of Bub3 and Spindly was detected in OSCC patients. High expression of Spindly, Bub3, or both was an independent prognostic indicator for cancer-specific survival and was associated with increased cellular proliferation. Accordingly, Bub3
RESULTS: Overexpression of Bub3 and Spindly was detected in OSCC patients. High expression of Spindly, Bub3, or both was an in …
[Expression and clinical significance of Spindly and Bub3 in oral squamous cell carcinoma].
Zheng J, Li TK, Bao Y, Zhang SX. Zheng J, et al. Shanghai Kou Qiang Yi Xue. 2020 Oct;29(5):528-532. Shanghai Kou Qiang Yi Xue. 2020. PMID: 33543222 Chinese.
The 5-year survival rate of patients with high expression of Spindly, Bub3, Spindly/Bub3 were significantly higher than the counterparts with low expression, and the 5-year survival rate of patients with high expression of Spindly/Bub3 was significantly lower …
The 5-year survival rate of patients with high expression of Spindly, Bub3, Spindly/Bub3 were significantly higher than the co …
335 results