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Therapeutic uses of drug-carrier systems for imidazole-containing dipeptide compounds that act as pharmacological chaperones and have significant impact on the treatment of chronic diseases associated with increased oxidative stress and the formation of advanced glycation end products.
Babizhayev MA, Yegorov YE. Babizhayev MA, et al. Crit Rev Ther Drug Carrier Syst. 2010;27(2):85-154. doi: 10.1615/critrevtherdrugcarriersyst.v27.i2.10. Crit Rev Ther Drug Carrier Syst. 2010. PMID: 20486899 Review.
The Role of Oxidative Stress in Diabetic Neuropathy: Generation of Free Radical Species in the Glycation Reaction and Gene Polymorphisms Encoding Antioxidant Enzymes to Genetic Susceptibility to Diabetic Neuropathy in Population of Type I Diabetic Patients.
Babizhayev MA, Strokov IA, Nosikov VV, Savel'yeva EL, Sitnikov VF, Yegorov YE, Lankin VZ. Babizhayev MA, et al. Cell Biochem Biophys. 2015 Apr;71(3):1425-43. doi: 10.1007/s12013-014-0365-y. Cell Biochem Biophys. 2015. PMID: 25427889
Reactive Oxygen Species and the Aging Eye: Specific Role of Metabolically Active Mitochondria in Maintaining Lens Function and in the Initiation of the Oxidation-Induced Maturity Onset Cataract--A Novel Platform of Mitochondria-Targeted Antioxidants With Broad Therapeutic Potential for Redox Regulation and Detoxification of Oxidants in Eye Diseases.
Babizhayev MA, Yegorov YE. Babizhayev MA, et al. Am J Ther. 2016 Jan-Feb;23(1):e98-117. doi: 10.1097/MJT.0b013e3181ea31ff. Am J Ther. 2016. PMID: 21048433 Review.
Telomere Attrition in Human Lens Epithelial Cells Associated with Oxidative Stress Provide a New Therapeutic Target for the Treatment, Dissolving and Prevention of Cataract with N-Acetylcarnosine Lubricant Eye Drops. Kinetic, Pharmacological and Activity-Dependent Separation of Therapeutic Targeting: Transcorneal Penetration and Delivery of L-Carnosine in the Aqueous Humor and Hormone-Like Hypothalamic Antiaging Effects of the Instilled Ophthalmic Drug Through a Safe Eye Medication Technique.
Babizhayev MA, Yegorov YE. Babizhayev MA, et al. Recent Pat Drug Deliv Formul. 2016;10(2):82-129. doi: 10.2174/1872211309666150618104657. Recent Pat Drug Deliv Formul. 2016. PMID: 26084629 Review.
An "enigmatic" L-carnosine (β-alanyl-L-histidine)? Cell proliferative activity as a fundamental property of a natural dipeptide inherent to traditional antioxidant, anti-aging biological activities: balancing and a hormonally correct agent, novel patented oral therapy dosage formulation for mobility, skeletal muscle power and functional performance, hypothalamic-pituitary- brain relationship in health, aging and stress studies.
Babizhayev MA, Yegorov YE. Babizhayev MA, et al. Recent Pat Drug Deliv Formul. 2015;9(1):1-64. doi: 10.2174/1872211309666141218145408. Recent Pat Drug Deliv Formul. 2015. PMID: 25524476 Review.
88 results