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Epigenetics and lifestyle.
Alegría-Torres JA, Baccarelli A, Bollati V. Alegría-Torres JA, et al. Among authors: baccarelli a. Epigenomics. 2011 Jun;3(3):267-77. doi: 10.2217/epi.11.22. Epigenomics. 2011. PMID: 22122337 Free PMC article. Review.
Most of the studies conducted so far have been centered on DNA methylation, whereas only a few investigations have studied lifestyle factors in relation to histone modifications and miRNAs. ...
Most of the studies conducted so far have been centered on DNA methylation, whereas only a few investigations have studied lifestyle …
Epigenetics and environmental chemicals.
Baccarelli A, Bollati V. Baccarelli A, et al. Curr Opin Pediatr. 2009 Apr;21(2):243-51. doi: 10.1097/mop.0b013e32832925cc. Curr Opin Pediatr. 2009. PMID: 19663042 Free PMC article. Review.
RECENT FINDINGS: In-vitro, animal, and human investigations have identified several classes of environmental chemicals that modify epigenetic marks, including metals (cadmium, arsenic, nickel, chromium, and methylmercury), peroxisome proliferators (trichloroethylene, dichloroacet …
RECENT FINDINGS: In-vitro, animal, and human investigations have identified several classes of environmental chemicals that modify epigeneti …
Environmental epigenetics.
Bollati V, Baccarelli A. Bollati V, et al. Among authors: baccarelli a. Heredity (Edinb). 2010 Jul;105(1):105-12. doi: 10.1038/hdy.2010.2. Epub 2010 Feb 24. Heredity (Edinb). 2010. PMID: 20179736 Free PMC article. Review.
Recent investigations have identified a number of environmental toxicants that cause altered methylation of human repetitive elements or genes. ...
Recent investigations have identified a number of environmental toxicants that cause altered methylation of human repetitive elements …
Collaboration between centres of the World Health Organization. Italy supports a Mexican university.
Alegria-Torres J, Baccarelli A. Alegria-Torres J, et al. Among authors: baccarelli a. Med Lav. 2010 Nov-Dec;101(6):453-7. Med Lav. 2010. PMID: 21141348
A sizeable percentage of Mexicans live under unfavorable conditions such as malnutrition, marginalization and overcrowding. Environmental injustice includes: indigenous exposed to wood smoke, families living in mining zones, children working and living in garbage dumps and
A sizeable percentage of Mexicans live under unfavorable conditions such as malnutrition, marginalization and overcrowding. Environme
The epigenetics of autoimmunity.
Meda F, Folci M, Baccarelli A, Selmi C. Meda F, et al. Among authors: baccarelli a. Cell Mol Immunol. 2011 May;8(3):226-36. doi: 10.1038/cmi.2010.78. Epub 2011 Jan 31. Cell Mol Immunol. 2011. PMID: 21278766 Free PMC article. Review.
Concordance rates in monozygotic twins are lower than 50% while genome-wide association studies propose numerous significant associations representing only a minority of patients. ...In recent years, several studies both in clinical settings and experimental models propose …
Concordance rates in monozygotic twins are lower than 50% while genome-wide association studies propose numerous significant associations re …
Environmental chemical exposures and human epigenetics.
Hou L, Zhang X, Wang D, Baccarelli A. Hou L, et al. Among authors: baccarelli a. Int J Epidemiol. 2012 Feb;41(1):79-105. doi: 10.1093/ije/dyr154. Epub 2011 Dec 13. Int J Epidemiol. 2012. PMID: 22253299 Free PMC article.
DNA methylation in repetitive elements and post-traumatic stress disorder: a case-control study of US military service members.
Rusiecki JA, Chen L, Srikantan V, Zhang L, Yan L, Polin ML, Baccarelli A. Rusiecki JA, et al. Among authors: baccarelli a. Epigenomics. 2012 Feb;4(1):29-40. doi: 10.2217/epi.11.116. Epigenomics. 2012. PMID: 22332656 Free PMC article.
METHODS: Cases (n = 75) had a postdeployment diagnosis of PTSD. Controls (n = 75) were randomly selected service members with no postdeployment PTSD diagnosis. ...
METHODS: Cases (n = 75) had a postdeployment diagnosis of PTSD. Controls (n = 75) were randomly selected service members with no post …
Nasal cell DNA methylation, inflammation, lung function and wheezing in children with asthma.
Baccarelli A, Rusconi F, Bollati V, Catelan D, Accetta G, Hou L, Barbone F, Bertazzi PA, Biggeri A. Baccarelli A, et al. Epigenomics. 2012 Feb;4(1):91-100. doi: 10.2217/epi.11.106. Epigenomics. 2012. PMID: 22332661 Free PMC article.
AIMS: DNA methylation is increasingly proposed as a mechanism for underlying asthma-related inflammation. However, epigenetic studies are constrained by uncertainties on whether samples that can be easily collected in human individuals can provide informative results. ...
AIMS: DNA methylation is increasingly proposed as a mechanism for underlying asthma-related inflammation. However, epigenetic studies …
Environmental exposures, epigenetics and cardiovascular disease.
Baccarelli A, Ghosh S. Baccarelli A, et al. Curr Opin Clin Nutr Metab Care. 2012 Jul;15(4):323-9. doi: 10.1097/MCO.0b013e328354bf5c. Curr Opin Clin Nutr Metab Care. 2012. PMID: 22669047 Free PMC article. Review.
Signatures of epigenetic dysregulation can be detected in peripheral blood samples, even within a few hours of environmental exposure. ...
Signatures of epigenetic dysregulation can be detected in peripheral blood samples, even within a few hours of environmental exposure …
Environmental epigenetics: a role in endocrine disease?
Fleisch AF, Wright RO, Baccarelli AA. Fleisch AF, et al. Among authors: baccarelli aa. J Mol Endocrinol. 2012 Aug 30;49(2):R61-7. doi: 10.1530/JME-12-0066. Print 2012 Oct. J Mol Endocrinol. 2012. PMID: 22798698 Free PMC article. Review.
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