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Synthetic and structure/activity studies on acid-substituted 2-arylphenols: discovery of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- hydroxyphenoxy]-propoxy]phenoxy]benzoic acid, a high-affinity leukotriene B4 receptor antagonist.
Sawyer JS, Bach NJ, Baker SR, Baldwin RF, Borromeo PS, Cockerham SL, Fleisch JH, Floreancig P, Froelich LL, Jackson WT, et al. Sawyer JS, et al. Among authors: bach nj. J Med Chem. 1995 Oct 27;38(22):4411-32. doi: 10.1021/jm00022a006. J Med Chem. 1995. PMID: 7473568
o-phenylphenols: potent and orally active leukotriene B4 receptor antagonists.
Sofia MJ, Floreancig P, Bach NJ, Baker SR, Cockerham SL, Fleisch JH, Froelich LL, Jackson WT, Marder P, Roman CR, et al. Sofia MJ, et al. Among authors: bach nj. J Med Chem. 1993 Nov 26;36(24):3978-81. doi: 10.1021/jm00076a029. J Med Chem. 1993. PMID: 7902871 No abstract available.
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides.
Dillard RD, Bach NJ, Draheim SE, Berry DR, Carlson DG, Chirgadze NY, Clawson DK, Hartley LW, Johnson LM, Jones ND, McKinney ER, Mihelich ED, Olkowski JL, Schevitz RW, Smith AC, Snyder DW, Sommers CD, Wery JP. Dillard RD, et al. Among authors: bach nj. J Med Chem. 1996 Dec 20;39(26):5119-36. doi: 10.1021/jm960485v. J Med Chem. 1996. PMID: 9005255
127 results