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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer.
Cameron EE, Bachman KE, Myöhänen S, Herman JG, Baylin SB. Cameron EE, et al. Among authors: bachman ke. Nat Genet. 1999 Jan;21(1):103-7. doi: 10.1038/5047. Nat Genet. 1999. PMID: 9916800
Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic.
Stone ML, Chiappinelli KB, Li H, Murphy LM, Travers ME, Topper MJ, Mathios D, Lim M, Shih IM, Wang TL, Hung CF, Bhargava V, Wiehagen KR, Cowley GS, Bachman KE, Strick R, Strissel PL, Baylin SB, Zahnow CA. Stone ML, et al. Among authors: bachman ke. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8583-E8584. doi: 10.1073/pnas.1811015115. Epub 2018 Sep 4. Proc Natl Acad Sci U S A. 2018. PMID: 30181297 Free PMC article. No abstract available.
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Stone ML, Chiappinelli KB, Li H, Murphy LM, Travers ME, Topper MJ, Mathios D, Lim M, Shih IM, Wang TL, Hung CF, Bhargava V, Wiehagen KR, Cowley GS, Bachman KE, Strick R, Strissel PL, Baylin SB, Zahnow CA. Stone ML, et al. Among authors: bachman ke. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10981-E10990. doi: 10.1073/pnas.1712514114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203668 Free PMC article.
De novo CpG island methylation in human cancer cells.
Jair KW, Bachman KE, Suzuki H, Ting AH, Rhee I, Yen RW, Baylin SB, Schuebel KE. Jair KW, et al. Among authors: bachman ke. Cancer Res. 2006 Jan 15;66(2):682-92. doi: 10.1158/0008-5472.CAN-05-1980. Cancer Res. 2006. PMID: 16423997
p21(WAF1/CIP1) mediates the growth response to TGF-beta in human epithelial cells.
Bachman KE, Blair BG, Brenner K, Bardelli A, Arena S, Zhou S, Hicks J, De Marzo AM, Argani P, Park BH. Bachman KE, et al. Cancer Biol Ther. 2004 Feb;3(2):221-5. doi: 10.4161/cbt.3.2.666. Epub 2004 Feb 1. Cancer Biol Ther. 2004. PMID: 14726675
The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1.
Reese BE, Bachman KE, Baylin SB, Rountree MR. Reese BE, et al. Among authors: bachman ke. Mol Cell Biol. 2003 May;23(9):3226-36. doi: 10.1128/mcb.23.9.3226-3236.2003. Mol Cell Biol. 2003. PMID: 12697822 Free PMC article.
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.
Bachman KE, Park BH, Rhee I, Rajagopalan H, Herman JG, Baylin SB, Kinzler KW, Vogelstein B. Bachman KE, et al. Cancer Cell. 2003 Jan;3(1):89-95. doi: 10.1016/s1535-6108(02)00234-9. Cancer Cell. 2003. PMID: 12559178
Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density.
Galm O, Rountree MR, Bachman KE, Jair KW, Baylin SB, Herman JG. Galm O, et al. Among authors: bachman ke. Genome Res. 2002 Jan;12(1):153-7. doi: 10.1101/gr.202501. Genome Res. 2002. PMID: 11779840 Free PMC article.
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Rhee I, Bachman KE, Park BH, Jair KW, Yen RW, Schuebel KE, Cui H, Feinberg AP, Lengauer C, Kinzler KW, Baylin SB, Vogelstein B. Rhee I, et al. Among authors: bachman ke. Nature. 2002 Apr 4;416(6880):552-6. doi: 10.1038/416552a. Nature. 2002. PMID: 11932749
Tamoxifen-stimulated growth of breast cancer due to p21 loss.
Abukhdeir AM, Vitolo MI, Argani P, De Marzo AM, Karakas B, Konishi H, Gustin JP, Lauring J, Garay JP, Pendleton C, Konishi Y, Blair BG, Brenner K, Garrett-Mayer E, Carraway H, Bachman KE, Park BH. Abukhdeir AM, et al. Among authors: bachman ke. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):288-93. doi: 10.1073/pnas.0710887105. Epub 2007 Dec 27. Proc Natl Acad Sci U S A. 2008. PMID: 18162533 Free PMC article.
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