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Discordant effects of glucosamine on insulin-stimulated glucose metabolism and phosphatidylinositol 3-kinase activity.
Hawkins M, Hu M, Yu J, Eder H, Vuguin P, She L, Barzilai N, Leiser M, Backer JM, Rossetti L. Hawkins M, et al. J Biol Chem. 1999 Oct 29;274(44):31312-9. doi: 10.1074/jbc.274.44.31312. J Biol Chem. 1999. PMID: 10531330
Specific requirement for the p85-p110alpha phosphatidylinositol 3-kinase during epidermal growth factor-stimulated actin nucleation in breast cancer cells.
Hill K, Welti S, Yu J, Murray JT, Yip SC, Condeelis JS, Segall JE, Backer JM. Hill K, et al. J Biol Chem. 2000 Feb 11;275(6):3741-4. doi: 10.1074/jbc.275.6.3741. J Biol Chem. 2000. PMID: 10660520
Kinase insert domain receptor (KDR) extracellular immunoglobulin-like domains 4-7 contain structural features that block receptor dimerization and vascular endothelial growth factor-induced signaling.
Tao Q, Backer MV, Backer JM, Terman BI. Tao Q, et al. J Biol Chem. 2001 Jun 15;276(24):21916-23. doi: 10.1074/jbc.M100763200. Epub 2001 Mar 16. J Biol Chem. 2001. PMID: 11399777
N-terminal domains of the class ia phosphoinositide 3-kinase regulatory subunit play a role in cytoskeletal but not mitogenic signaling.
Hill KM, Huang Y, Yip SC, Yu J, Segall JE, Backer JM. Hill KM, et al. J Biol Chem. 2001 May 11;276(19):16374-8. doi: 10.1074/jbc.M006985200. Epub 2001 Feb 14. J Biol Chem. 2001. PMID: 11278326
Regulation of the p85/p110alpha phosphatidylinositol 3'-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains.
Yu J, Wjasow C, Backer JM. Yu J, et al. J Biol Chem. 1998 Nov 13;273(46):30199-203. doi: 10.1074/jbc.273.46.30199. J Biol Chem. 1998. PMID: 9804776
., and Backer, J. M. (1998) Mol. Cell. Biol. 18, 1379-1387). We now define the domains of p85 required for inhibition of p110alpha. ...
., and Backer, J. M. (1998) Mol. Cell. Biol. 18, 1379-1387). We now define the domains of p85 required for inhibition of p110alpha. . …
In vitro binding and phosphorylation of insulin receptor substrate 1 by the insulin receptor. Role of interactions mediated by the phosphotyrosine-binding domain and the pleckstrin-homology domain.
Backer JM, Wjasow C, Zhang Y. Backer JM, et al. Eur J Biochem. 1997 Apr 1;245(1):91-6. doi: 10.1111/j.1432-1033.1997.t01-1-00091.x. Eur J Biochem. 1997. PMID: 9128728
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