Backes BJ - Search Results

1

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries.

Harris JL, Backes BJ, Leonetti F, Mahrus S, Ellman JA, Craik CS. Harris JL, et al. Among authors: backes bj. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7754-9. doi: 10.1073/pnas.140132697. Proc Natl Acad Sci U S A. 2000. PMID: 10869434 Free PMC article.

2

Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore.

Maly DJ, Leonetti F, Backes BJ, Dauber DS, Harris JL, Craik CS, Ellman JA. Maly DJ, et al. Among authors: backes bj. J Org Chem. 2002 Feb 8;67(3):910-5. doi: 10.1021/jo016140o. J Org Chem. 2002. PMID: 11856036

3

Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.

Backes BJ, Harris JL, Leonetti F, Craik CS, Ellman JA. Backes BJ, et al. Nat Biotechnol. 2000 Feb;18(2):187-93. doi: 10.1038/72642. Nat Biotechnol. 2000. PMID: 10657126

4

Definition of the extended substrate specificity determinants for beta-tryptases I and II.

Harris JL, Niles A, Burdick K, Maffitt M, Backes BJ, Ellman JA, Kuntz I, Haak-Frendscho M, Craik CS. Harris JL, et al. Among authors: backes bj. J Biol Chem. 2001 Sep 14;276(37):34941-7. doi: 10.1074/jbc.M102997200. Epub 2001 Jul 3. J Biol Chem. 2001. PMID: 11438529 Free article.

5

A strategy to profile prime and non-prime proteolytic substrate specificity.

Petrassi HM, Williams JA, Li J, Tumanut C, Ek J, Nakai T, Masick B, Backes BJ, Harris JL. Petrassi HM, et al. Among authors: backes bj. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3162-6. doi: 10.1016/j.bmcl.2005.04.019. Bioorg Med Chem Lett. 2005. PMID: 15878267

6

Solid support linker strategies.

Backes BJ, Ellman JA. Backes BJ, et al. Curr Opin Chem Biol. 1997 Jun;1(1):86-93. doi: 10.1016/s1367-5931(97)80113-5. Curr Opin Chem Biol. 1997. PMID: 9667836 Review.

7

Substrate specificity of the human proteasome.

Harris JL, Alper PB, Li J, Rechsteiner M, Backes BJ. Harris JL, et al. Among authors: backes bj. Chem Biol. 2001 Dec;8(12):1131-41. doi: 10.1016/s1074-5521(01)00080-1. Chem Biol. 2001. PMID: 11755392

8

Biochemical analysis of the 20 S proteasome of Trypanosoma brucei.

Wang CC, Bozdech Z, Liu CL, Shipway A, Backes BJ, Harris JL, Bogyo M. Wang CC, et al. Among authors: backes bj. J Biol Chem. 2003 May 2;278(18):15800-8. doi: 10.1074/jbc.M300195200. Epub 2003 Feb 24. J Biol Chem. 2003. PMID: 12600991 Free article.

9

Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays.

Harris J, Mason DE, Li J, Burdick KW, Backes BJ, Chen T, Shipway A, Van Heeke G, Gough L, Ghaemmaghami A, Shakib F, Debaene F, Winssinger N. Harris J, et al. Among authors: backes bj. Chem Biol. 2004 Oct;11(10):1361-72. doi: 10.1016/j.chembiol.2004.08.008. Chem Biol. 2004. PMID: 15489163

10

Biochemical characterization of prostasin, a channel activating protease.

Shipway A, Danahay H, Williams JA, Tully DC, Backes BJ, Harris JL. Shipway A, et al. Among authors: backes bj. Biochem Biophys Res Commun. 2004 Nov 12;324(2):953-63. doi: 10.1016/j.bbrc.2004.09.123. Biochem Biophys Res Commun. 2004. PMID: 15474520

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