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192 results
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Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2-mediated presystemic metabolism.
Granfors MT, Backman JT, Neuvonen M, Neuvonen PJ. Granfors MT, et al. Among authors: backman jt. Clin Pharmacol Ther. 2004 Dec;76(6):598-606. doi: 10.1016/j.clpt.2004.08.018. Clin Pharmacol Ther. 2004. PMID: 15592331 Clinical Trial.
Azithromycin does not increase plasma concentrations of oral midazolam.
Backman JT, Olkkola KT, Neuvonen PJ. Backman JT, et al. Int J Clin Pharmacol Ther. 1995 Jun;33(6):356-9. Int J Clin Pharmacol Ther. 1995. PMID: 7582388 Clinical Trial.
The effect of erythromycin on the pharmacokinetics and pharmacodynamics of zopiclone.
Aranko K, Luurila H, Backman JT, Neuvonen PJ, Olkkola KT. Aranko K, et al. Among authors: backman jt. Br J Clin Pharmacol. 1994 Oct;38(4):363-7. doi: 10.1111/j.1365-2125.1994.tb04367.x. Br J Clin Pharmacol. 1994. PMID: 7833227 Free PMC article. Clinical Trial.
A pharmacokinetic interaction between roxithromycin and midazolam.
Backman JT, Aranko K, Himberg JJ, Olkkola KT. Backman JT, et al. Eur J Clin Pharmacol. 1994;46(6):551-5. doi: 10.1007/BF00196114. Eur J Clin Pharmacol. 1994. PMID: 7995324 Clinical Trial.
Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.
Olkkola KT, Backman JT, Neuvonen PJ. Olkkola KT, et al. Among authors: backman jt. Clin Pharmacol Ther. 1994 May;55(5):481-5. doi: 10.1038/clpt.1994.60. Clin Pharmacol Ther. 1994. PMID: 8181191 Clinical Trial.
Dose of midazolam should be reduced during diltiazem and verapamil treatments.
Backman JT, Olkkola KT, Aranko K, Himberg JJ, Neuvonen PJ. Backman JT, et al. Br J Clin Pharmacol. 1994 Mar;37(3):221-5. doi: 10.1111/j.1365-2125.1994.tb04266.x. Br J Clin Pharmacol. 1994. PMID: 8198928 Free PMC article. Clinical Trial.
Rifampin drastically reduces plasma concentrations and effects of oral midazolam.
Backman JT, Olkkola KT, Neuvonen PJ. Backman JT, et al. Clin Pharmacol Ther. 1996 Jan;59(1):7-13. doi: 10.1016/S0009-9236(96)90018-1. Clin Pharmacol Ther. 1996. PMID: 8549036 Clinical Trial.
Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin.
Backman JT, Olkkola KT, Ojala M, Laaksovirta H, Neuvonen PJ. Backman JT, et al. Epilepsia. 1996 Mar;37(3):253-7. doi: 10.1111/j.1528-1157.1996.tb00021.x. Epilepsia. 1996. PMID: 8598183
Triazolam is ineffective in patients taking rifampin.
Villikka K, Kivistö KT, Backman JT, Olkkola KT, Neuvonen PJ. Villikka K, et al. Among authors: backman jt. Clin Pharmacol Ther. 1997 Jan;61(1):8-14. doi: 10.1016/S0009-9236(97)90176-4. Clin Pharmacol Ther. 1997. PMID: 9024169 Clinical Trial.
The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.
Backman JT, Kivistö KT, Olkkola KT, Neuvonen PJ. Backman JT, et al. Eur J Clin Pharmacol. 1998 Mar;54(1):53-8. doi: 10.1007/s002280050420. Eur J Clin Pharmacol. 1998. PMID: 9591931 Clinical Trial.
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