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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2004 3
2005 6
2006 7
2007 11
2008 9
2009 6
2010 10
2011 6
2012 11
2013 15
2014 22
2015 11
2016 13
2017 22
2018 24
2019 15
2020 20
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2025 14
2026 7

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271 results

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Page 1
Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
Makarova KS, Wolf YI, Iranzo J, Shmakov SA, Alkhnbashi OS, Brouns SJJ, Charpentier E, Cheng D, Haft DH, Horvath P, Moineau S, Mojica FJM, Scott D, Shah SA, Siksnys V, Terns MP, Venclovas Č, White MF, Yakunin AF, Yan W, Zhang F, Garrett RA, Backofen R, van der Oost J, Barrangou R, Koonin EV. Makarova KS, et al. Among authors: backofen r. Nat Rev Microbiol. 2020 Feb;18(2):67-83. doi: 10.1038/s41579-019-0299-x. Epub 2019 Dec 19. Nat Rev Microbiol. 2020. PMID: 31857715 Free PMC article. Review.
An updated evolutionary classification of CRISPR-Cas systems.
Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, Saunders SJ, Barrangou R, Brouns SJ, Charpentier E, Haft DH, Horvath P, Moineau S, Mojica FJ, Terns RM, Terns MP, White MF, Yakunin AF, Garrett RA, van der Oost J, Backofen R, Koonin EV. Makarova KS, et al. Among authors: backofen r. Nat Rev Microbiol. 2015 Nov;13(11):722-36. doi: 10.1038/nrmicro3569. Epub 2015 Sep 28. Nat Rev Microbiol. 2015. PMID: 26411297 Free PMC article. Review.
CRISPR-Cas bioinformatics.
Alkhnbashi OS, Meier T, Mitrofanov A, Backofen R, Voß B. Alkhnbashi OS, et al. Among authors: backofen r. Methods. 2020 Feb 1;172:3-11. doi: 10.1016/j.ymeth.2019.07.013. Epub 2019 Jul 19. Methods. 2020. PMID: 31326596 Review.
Partial RNA design.
Runge F, Franke J, Fertmann D, Backofen R, Hutter F. Runge F, et al. Among authors: backofen r. Bioinformatics. 2024 Jun 28;40(Suppl 1):i437-i445. doi: 10.1093/bioinformatics/btae222. Bioinformatics. 2024. PMID: 38940170 Free PMC article.
Comparative RNA Genomics.
Backofen R, Gorodkin J, Hofacker IL, Stadler PF. Backofen R, et al. Methods Mol Biol. 2024;2802:347-393. doi: 10.1007/978-1-0716-3838-5_12. Methods Mol Biol. 2024. PMID: 38819565
An updated evolutionary classification of CRISPR-Cas systems including rare variants.
Makarova KS, Shmakov SA, Wolf YI, Mutz P, Altae-Tran H, Beisel CL, Brouns SJJ, Charpentier E, Cheng D, Doudna J, Haft DH, Horvath P, Moineau S, Mojica FJM, Pausch P, Pinilla-Redondo R, Shah SA, Siksnys V, Terns MP, Tordoff J, Venclovas Č, White MF, Yakunin AF, Zhang F, Garrett RA, Backofen R, van der Oost J, Barrangou R, Koonin EV. Makarova KS, et al. Among authors: backofen r. Nat Microbiol. 2025 Dec;10(12):3346-3361. doi: 10.1038/s41564-025-02180-8. Epub 2025 Nov 6. Nat Microbiol. 2025. PMID: 41198952 Free PMC article.
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Among authors: backofen r. Nat Cell Biol. 2021 Jul;23(7):704-717. doi: 10.1038/s41556-021-00707-9. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253898 Free PMC article.
A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation.
Forster PM, Jakob MO, Yusuf D, Bubeck M, Limberger H, Luo Y, Thieme P, Polici A, Sterczyk N, Boulekou S, Bartel L, Cosovanu C, Witkowski M, González-Acera M, Kühl AA, Weidinger C; TRR241 IBDome Consortium; Backofen R, Hegazy AN, Patankar JV, Klose CSN. Forster PM, et al. Among authors: backofen r. Neuron. 2025 May 7;113(9):1333-1351.e7. doi: 10.1016/j.neuron.2025.02.018. Epub 2025 Mar 17. Neuron. 2025. PMID: 40101721 Free article.
Computational analysis of CLIP-seq data.
Uhl M, Houwaart T, Corrado G, Wright PR, Backofen R. Uhl M, et al. Among authors: backofen r. Methods. 2017 Apr 15;118-119:60-72. doi: 10.1016/j.ymeth.2017.02.006. Epub 2017 Feb 22. Methods. 2017. PMID: 28254606 Review.
271 results