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In the absence of cellular poly (A) binding protein, the glycolytic enzyme GAPDH translocated to the cell nucleus and activated the GAPDH mediated apoptotic pathway by enhancing acetylation and serine 46 phosphorylation of p53.
Thangima Zannat M, Bhattacharjee RB, Bag J. Thangima Zannat M, et al. Among authors: bag j. Biochem Biophys Res Commun. 2011 Jun 3;409(2):171-6. doi: 10.1016/j.bbrc.2011.04.094. Epub 2011 Apr 24. Biochem Biophys Res Commun. 2011. PMID: 21539808
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