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The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling.
Ochodnicka-Mackovicova K, Bahjat M, Maas C, van der Veen A, Bloedjes TA, de Bruin AM, van Andel H, Schrader CE, Hendriks RW, Verhoeyen E, Bende RJ, van Noesel CJ, Guikema JE. Ochodnicka-Mackovicova K, et al. Among authors: bahjat m. J Immunol. 2016 Oct 1;197(7):2918-29. doi: 10.4049/jimmunol.1501989. Epub 2016 Aug 24. J Immunol. 2016. PMID: 27559048 Free article.
NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity.
Ochodnicka-Mackovicova K, Bahjat M, Bloedjes TA, Maas C, de Bruin AM, Bende RJ, van Noesel CJ, Guikema JE. Ochodnicka-Mackovicova K, et al. Among authors: bahjat m. Blood. 2015 Sep 10;126(11):1324-35. doi: 10.1182/blood-2015-01-621623. Epub 2015 Jul 7. Blood. 2015. PMID: 26153519 Free PMC article.
Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.
Carreras Puigvert J, von Stechow L, Siddappa R, Pines A, Bahjat M, Haazen LC, Olsen JV, Vrieling H, Meerman JH, Mullenders LH, van de Water B, Danen EH. Carreras Puigvert J, et al. Among authors: bahjat m. Sci Signal. 2013 Jan 22;6(259):ra5. doi: 10.1126/scisignal.2003208. Sci Signal. 2013. PMID: 23354688
Potential epigenetic therapeutics for atherosclerosis treatment.
Nicorescu I, Dallinga GM, de Winther MPJ, Stroes ESG, Bahjat M. Nicorescu I, et al. Among authors: bahjat m. Atherosclerosis. 2019 Feb;281:189-197. doi: 10.1016/j.atherosclerosis.2018.10.006. Epub 2018 Oct 8. Atherosclerosis. 2019. PMID: 30340764 Review.
Design and In Vitro Evaluation of Eudragit-Based Extended Release Diltiazem Microspheres for Once- and Twice-Daily Administration: The Effect of Coating on Drug Release Behavior.
Bolourchian N, Bahjat M. Bolourchian N, et al. Among authors: bahjat m. Turk J Pharm Sci. 2019 Sep;16(3):340-347. doi: 10.4274/tjps.galenos.2018.24861. Epub 2019 Jul 10. Turk J Pharm Sci. 2019. PMID: 32454733 Free PMC article.
Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a).
Stiekema LCA, Prange KHM, Hoogeveen RM, Verweij SL, Kroon J, Schnitzler JG, Dzobo KE, Cupido AJ, Tsimikas S, Stroes ESG, de Winther MPJ, Bahjat M. Stiekema LCA, et al. Among authors: bahjat m. Eur Heart J. 2020 Jun 21;41(24):2262-2271. doi: 10.1093/eurheartj/ehaa171. Eur Heart J. 2020. PMID: 32268367 Free PMC article.
The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors.
Bahjat M, de Wilde G, van Dam T, Maas C, Bloedjes T, Bende RJ, van Noesel CJM, Luijks DM, Eldering E, Kersten MJ, Guikema JEJ. Bahjat M, et al. Cell Cycle. 2019 Sep;18(18):2307-2322. doi: 10.1080/15384101.2019.1646068. Epub 2019 Jul 26. Cell Cycle. 2019. PMID: 31349760 Free PMC article.
Platelet lysate induces chondrogenic differentiation of umbilical cord-derived mesenchymal stem cells.
Hassan G, Bahjat M, Kasem I, Soukkarieh C, Aljamali M. Hassan G, et al. Among authors: bahjat m. Cell Mol Biol Lett. 2018 Mar 20;23:11. doi: 10.1186/s11658-018-0080-6. eCollection 2018. Cell Mol Biol Lett. 2018. PMID: 29568314 Free PMC article.