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Mutant forms of tumour necrosis factor receptor I that occur in TNF-receptor-associated periodic syndrome retain signalling functions but show abnormal behaviour.
Todd I, Radford PM, Draper-Morgan KA, McIntosh R, Bainbridge S, Dickinson P, Jamhawi L, Sansaridis M, Huggins ML, Tighe PJ, Powell RJ. Todd I, et al. Among authors: bainbridge s. Immunology. 2004 Sep;113(1):65-79. doi: 10.1111/j.1365-2567.2004.01942.x. Immunology. 2004. PMID: 15312137 Free PMC article.
Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line.
Rebelo SL, Amel-Kashipaz MR, Radford PM, Bainbridge SE, Fiets R, Fang J, McDermott EM, Powell RJ, Todd I, Tighe PJ. Rebelo SL, et al. Arthritis Rheum. 2009 Jan;60(1):269-80. doi: 10.1002/art.24147. Arthritis Rheum. 2009. PMID: 19116900
A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing.
Todd I, Negm OH, Reps J, Radford P, Figueredo G, McDermott EM, Drewe E, Powell RJ, Bainbridge S, Hamed M, Crouch S, Garibaldi J, St-Gallay S, Fairclough LC, Tighe PJ. Todd I, et al. Among authors: bainbridge s. Pharmacol Res. 2017 Nov;125(Pt B):188-200. doi: 10.1016/j.phrs.2017.08.012. Epub 2017 Aug 30. Pharmacol Res. 2017. PMID: 28860008
PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline.
Barton SJ, Koppelman GH, Vonk JM, Browning CA, Nolte IM, Stewart CE, Bainbridge S, Mutch S, Rose-Zerilli MJ, Postma DS, Maniatis N, Henry AP, Hall IP, Holgate ST, Tighe P, Holloway JW, Sayers I. Barton SJ, et al. Among authors: bainbridge s. J Allergy Clin Immunol. 2009 Jun;123(6):1391-400.e17. doi: 10.1016/j.jaci.2009.03.014. Epub 2009 May 13. J Allergy Clin Immunol. 2009. PMID: 19443020
IFPA Meeting 2013 Workshop Report I: diabetes in pregnancy, maternal dyslipidemia in pregnancy, oxygen in placental development, stem cells and pregnancy pathology.
Abumaree MH, Alahari S, Albrecht C, Aye IL, Bainbridge S, Chauvin S, Clifton VL, Desoye G, Ermini L, Giuffrida D, Graham CH, Huang QT, Kalionis B, Lager S, Leach L, Li Y, Litvack ML, Nuzzo AM, Moretto-Zita M, O'Tierney-Ginn P, Powell T, Rolfo A, Salomon C, Serov A, Westwood M, Yung HW, Lash GE. Abumaree MH, et al. Among authors: bainbridge s. Placenta. 2014 Feb;35 Suppl:S4-9. doi: 10.1016/j.placenta.2013.11.010. Epub 2013 Dec 1. Placenta. 2014. PMID: 24321782
62 results