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Effects of piperacillin/tazobactam on Clostridium difficile growth and toxin production in a human gut model.
Baines SD, Freeman J, Wilcox MH. Baines SD, et al. J Antimicrob Chemother. 2005 Jun;55(6):974-82. doi: 10.1093/jac/dki120. Epub 2005 Apr 28. J Antimicrob Chemother. 2005. PMID: 15860551
In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile.
Corbett D, Wise A, Birchall S, Warn P, Baines SD, Crowther G, Freeman J, Chilton CH, Vernon J, Wilcox MH, Vickers RJ. Corbett D, et al. Among authors: baines sd. J Antimicrob Chemother. 2015;70(6):1751-6. doi: 10.1093/jac/dkv006. Epub 2015 Feb 3. J Antimicrob Chemother. 2015. PMID: 25652750 Free PMC article.
SMT19969 as a treatment for Clostridium difficile infection: an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model.
Baines SD, Crowther GS, Freeman J, Todhunter S, Vickers R, Wilcox MH. Baines SD, et al. J Antimicrob Chemother. 2015 Jan;70(1):182-9. doi: 10.1093/jac/dku324. Epub 2014 Sep 3. J Antimicrob Chemother. 2015. PMID: 25190720 Free PMC article.
In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection.
Chilton CH, Crowther GS, Baines SD, Todhunter SL, Freeman J, Locher HH, Athanasiou A, Wilcox MH. Chilton CH, et al. Among authors: baines sd. J Antimicrob Chemother. 2014 Mar;69(3):697-705. doi: 10.1093/jac/dkt411. Epub 2013 Oct 14. J Antimicrob Chemother. 2014. PMID: 24128668
The changing epidemiology of Clostridium difficile infections.
Freeman J, Bauer MP, Baines SD, Corver J, Fawley WN, Goorhuis B, Kuijper EJ, Wilcox MH. Freeman J, et al. Among authors: baines sd. Clin Microbiol Rev. 2010 Jul;23(3):529-49. doi: 10.1128/CMR.00082-09. Clin Microbiol Rev. 2010. PMID: 20610822 Free PMC article. Review.
Evaluation of the effect of oritavancin on Clostridium difficile spore germination, outgrowth and recovery.
Chilton CH, Freeman J, Baines SD, Crowther GS, Nicholson S, Wilcox MH. Chilton CH, et al. Among authors: baines sd. J Antimicrob Chemother. 2013 Sep;68(9):2078-82. doi: 10.1093/jac/dkt160. Epub 2013 Jun 11. J Antimicrob Chemother. 2013. PMID: 23759507
Measurement of toxin production by Clostridium difficile.
Freeman J, Fawley W, Baines S, Wilcox M. Freeman J, et al. Among authors: baines s. Lancet. 2006 Mar 25;367(9515):982-3; author reply 983-4. doi: 10.1016/S0140-6736(06)68417-1. Lancet. 2006. PMID: 16564352 No abstract available.
Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota.
Crowther GS, Chilton CH, Todhunter SL, Nicholson S, Freeman J, Baines SD, Wilcox MH. Crowther GS, et al. Among authors: baines sd. PLoS One. 2014 Feb 6;9(2):e88396. doi: 10.1371/journal.pone.0088396. eCollection 2014. PLoS One. 2014. PMID: 24516647 Free PMC article.
Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease.
Eyre DW, Walker AS, Freeman J, Baines SD, Fawley WN, Chilton CH, Griffiths D, Vaughan A, Crook DW, Peto TE, Wilcox MH. Eyre DW, et al. Among authors: baines sd. PLoS One. 2013 May 15;8(5):e63540. doi: 10.1371/journal.pone.0063540. Print 2013. PLoS One. 2013. PMID: 23691061 Free PMC article.
Mecillinam: a low-risk antimicrobial agent for induction of Clostridium difficile infection in an in vitro human gut model.
Baines SD, O'Connor R, Huscroft G, Saxton K, Freeman J, Wilcox MH. Baines SD, et al. J Antimicrob Chemother. 2009 Apr;63(4):838-9. doi: 10.1093/jac/dkp017. Epub 2009 Feb 11. J Antimicrob Chemother. 2009. PMID: 19211576 No abstract available.
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