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Effects of combined exenatide and pioglitazone therapy on hepatic fat content in type 2 diabetes.
Sathyanarayana P, Jogi M, Muthupillai R, Krishnamurthy R, Samson SL, Bajaj M. Sathyanarayana P, et al. Among authors: bajaj m. Obesity (Silver Spring). 2011 Dec;19(12):2310-5. doi: 10.1038/oby.2011.152. Epub 2011 Jun 9. Obesity (Silver Spring). 2011. PMID: 21660077 Clinical Trial.
Hypoadiponectinemia is closely associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects.
Kashyap SR, Roman LJ, Mandarino L, DeFronzo R, Bajaj M. Kashyap SR, et al. Among authors: bajaj m. Metab Syndr Relat Disord. 2010 Oct;8(5):459-63. doi: 10.1089/met.2010.0018. Metab Syndr Relat Disord. 2010. PMID: 20854065 Free PMC article.
Insulin resistance is associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects.
Kashyap SR, Roman LJ, Lamont J, Masters BS, Bajaj M, Suraamornkul S, Belfort R, Berria R, Kellogg DL Jr, Liu Y, DeFronzo RA. Kashyap SR, et al. Among authors: bajaj m. J Clin Endocrinol Metab. 2005 Feb;90(2):1100-5. doi: 10.1210/jc.2004-0745. Epub 2004 Nov 23. J Clin Endocrinol Metab. 2005. PMID: 15562034
We determined nitric oxide synthase (NOS) activity in skeletal muscle of 10 type 2 diabetic (hemoglobin A(1C) = 6.8 +/- 0.1%) and 11 control subjects under basal conditions and during an 80 mU/m(2).min euglycemic insulin clamp performed with vastus lateralis muscle biopsie …
We determined nitric oxide synthase (NOS) activity in skeletal muscle of 10 type 2 diabetic (hemoglobin A(1C) = 6.8 +/- 0.1%) and 11 control …
Effects of pioglitazone on intramyocellular fat metabolism in patients with type 2 diabetes mellitus.
Bajaj M, Baig R, Suraamornkul S, Hardies LJ, Coletta DK, Cline GW, Monroy A, Koul S, Sriwijitkamol A, Musi N, Shulman GI, DeFronzo RA. Bajaj M, et al. J Clin Endocrinol Metab. 2010 Apr;95(4):1916-23. doi: 10.1210/jc.2009-0911. Epub 2010 Feb 15. J Clin Endocrinol Metab. 2010. PMID: 20157197 Free PMC article.
RESEARCH DESIGN: Twenty-four T2DM subjects (glycosylated hemoglobin = 8.3 +/- 0.4%) participated in three similar study protocols before and after 4 months of 45 mg/d pioglitazone treatment: 1) 3-h euglycemic insulin (80 mU/m(2) . min) clamp with measurement of intramyocel …
RESEARCH DESIGN: Twenty-four T2DM subjects (glycosylated hemoglobin = 8.3 +/- 0.4%) participated in three similar study protocols before and …
Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model.
Samson SL, Gonzalez EV, Yechoor V, Bajaj M, Oka K, Chan L. Samson SL, et al. Among authors: bajaj m. Mol Ther. 2008 Nov;16(11):1805-12. doi: 10.1038/mt.2008.198. Epub 2008 Sep 9. Mol Ther. 2008. PMID: 18781141 Free PMC article.
Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients.
Bajaj M, Suraamornkul S, Romanelli A, Cline GW, Mandarino LJ, Shulman GI, DeFronzo RA. Bajaj M, et al. Diabetes. 2005 Nov;54(11):3148-53. doi: 10.2337/diabetes.54.11.3148. Diabetes. 2005. PMID: 16249438 Clinical Trial.
Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle.
Richardson DK, Kashyap S, Bajaj M, Cusi K, Mandarino SJ, Finlayson J, DeFronzo RA, Jenkinson CP, Mandarino LJ. Richardson DK, et al. Among authors: bajaj m. J Biol Chem. 2005 Mar 18;280(11):10290-7. doi: 10.1074/jbc.M408985200. Epub 2004 Dec 14. J Biol Chem. 2005. PMID: 15598661
Sustained reduction in plasma free fatty acid concentration improves insulin action without altering plasma adipocytokine levels in subjects with strong family history of type 2 diabetes.
Bajaj M, Suraamornkul S, Kashyap S, Cusi K, Mandarino L, DeFronzo RA. Bajaj M, et al. J Clin Endocrinol Metab. 2004 Sep;89(9):4649-55. doi: 10.1210/jc.2004-0224. J Clin Endocrinol Metab. 2004. PMID: 15356076
To investigate the effect of a sustained (7-d) decrease in plasma free fatty acid (FFA) concentration in individuals genetically predisposed to develop type 2 diabetes mellitus (T2DM), we studied the effect of acipimox, a potent inhibitor of lipolysis, on insulin action and adipo …
To investigate the effect of a sustained (7-d) decrease in plasma free fatty acid (FFA) concentration in individuals genetically predisposed …
Effect of pioglitazone on circulating adipocytokine levels and insulin sensitivity in type 2 diabetic patients.
Miyazaki Y, Mahankali A, Wajcberg E, Bajaj M, Mandarino LJ, DeFronzo RA. Miyazaki Y, et al. Among authors: bajaj m. J Clin Endocrinol Metab. 2004 Sep;89(9):4312-9. doi: 10.1210/jc.2004-0190. J Clin Endocrinol Metab. 2004. PMID: 15356026 Clinical Trial.
Twenty-three subjects with T2DM (age 54 +/- 2 yr, body mass index 29 +/- 1 kg/m(2)) were randomly assigned to receive placebo (n = 11) or PIO, 45 mg/d (n = 12), for 4 months. Before and after treatment, subjects received a 75-g oral glucose tolerance test (OGTT); euglycemi …
Twenty-three subjects with T2DM (age 54 +/- 2 yr, body mass index 29 +/- 1 kg/m(2)) were randomly assigned to receive placebo (n = 11 …
Type 2 diabetes in South Asians: a pathophysiologic focus on the Asian-Indian epidemic.
Bajaj M, Banerji MA. Bajaj M, et al. Curr Diab Rep. 2004 Jun;4(3):213-8. doi: 10.1007/s11892-004-0026-4. Curr Diab Rep. 2004. PMID: 15132888 Review.
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