Baker D - Search Results

1

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.

Janda CY, Dang LT, You C, Chang J, de Lau W, Zhong ZA, Yan KS, Marecic O, Siepe D, Li X, Moody JD, Williams BO, Clevers H, Piehler J, Baker D, Kuo CJ, Garcia KC. Janda CY, et al. Among authors: baker d. Nature. 2017 May 11;545(7653):234-237. doi: 10.1038/nature22306. Epub 2017 May 3. Nature. 2017. PMID: 28467818 Free PMC article.

2

Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130.

Boulanger MJ, Bankovich AJ, Kortemme T, Baker D, Garcia KC. Boulanger MJ, et al. Among authors: baker d. Mol Cell. 2003 Sep;12(3):577-89. doi: 10.1016/s1097-2765(03)00365-4. Mol Cell. 2003. PMID: 14527405 Free article.

3

High-resolution structure prediction and the crystallographic phase problem.

Qian B, Raman S, Das R, Bradley P, McCoy AJ, Read RJ, Baker D. Qian B, et al. Among authors: baker d. Nature. 2007 Nov 8;450(7167):259-64. doi: 10.1038/nature06249. Epub 2007 Oct 14. Nature. 2007. PMID: 17934447 Free PMC article.

4

Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design.

Wang L, Althoff EA, Bolduc J, Jiang L, Moody J, Lassila JK, Giger L, Hilvert D, Stoddard B, Baker D. Wang L, et al. Among authors: baker d. J Mol Biol. 2012 Jan 20;415(3):615-25. doi: 10.1016/j.jmb.2011.10.043. Epub 2011 Nov 3. J Mol Biol. 2012. PMID: 22075445 Free PMC article.

5

Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing.

Whitehead TA, Chevalier A, Song Y, Dreyfus C, Fleishman SJ, De Mattos C, Myers CA, Kamisetty H, Blair P, Wilson IA, Baker D. Whitehead TA, et al. Among authors: baker d. Nat Biotechnol. 2012 May 27;30(6):543-8. doi: 10.1038/nbt.2214. Nat Biotechnol. 2012. PMID: 22634563 Free PMC article.

6

Principles for designing ideal protein structures.

Koga N, Tatsumi-Koga R, Liu G, Xiao R, Acton TB, Montelione GT, Baker D. Koga N, et al. Among authors: baker d. Nature. 2012 Nov 8;491(7423):222-7. doi: 10.1038/nature11600. Nature. 2012. PMID: 23135467 Free PMC article.

7

Improved low-resolution crystallographic refinement with Phenix and Rosetta.

DiMaio F, Echols N, Headd JJ, Terwilliger TC, Adams PD, Baker D. DiMaio F, et al. Among authors: baker d. Nat Methods. 2013 Nov;10(11):1102-4. doi: 10.1038/nmeth.2648. Epub 2013 Sep 29. Nat Methods. 2013. PMID: 24076763 Free PMC article.

8

Accurate design of co-assembling multi-component protein nanomaterials.

King NP, Bale JB, Sheffler W, McNamara DE, Gonen S, Gonen T, Yeates TO, Baker D. King NP, et al. Among authors: baker d. Nature. 2014 Jun 5;510(7503):103-8. doi: 10.1038/nature13404. Epub 2014 May 25. Nature. 2014. PMID: 24870237 Free PMC article.

9

Exploring the repeat protein universe through computational protein design.

Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Brunette TJ, et al. Among authors: baker d. Nature. 2015 Dec 24;528(7583):580-4. doi: 10.1038/nature16162. Epub 2015 Dec 16. Nature. 2015. PMID: 26675729 Free PMC article.

10

Rational design of α-helical tandem repeat proteins with closed architectures.

Doyle L, Hallinan J, Bolduc J, Parmeggiani F, Baker D, Stoddard BL, Bradley P. Doyle L, et al. Among authors: baker d. Nature. 2015 Dec 24;528(7583):585-8. doi: 10.1038/nature16191. Epub 2015 Dec 16. Nature. 2015. PMID: 26675735 Free PMC article.

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