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Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail.
Brasacchio D, Okabe J, Tikellis C, Balcerczyk A, George P, Baker EK, Calkin AC, Brownlee M, Cooper ME, El-Osta A. Brasacchio D, et al. Among authors: baker ek. Diabetes. 2009 May;58(5):1229-36. doi: 10.2337/db08-1666. Epub 2009 Feb 10. Diabetes. 2009. PMID: 19208907 Free PMC article.
MDR1, chemotherapy and chromatin remodeling.
Baker EK, El-Osta A. Baker EK, et al. Cancer Biol Ther. 2004 Sep;3(9):819-24. doi: 10.4161/cbt.3.9.1101. Epub 2004 Sep 23. Cancer Biol Ther. 2004. PMID: 15326379 Review.
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