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Page 1
Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists.
Bharate SB, Rodge A, Joshi RK, Kaur J, Srinivasan S, Kumar SS, Kulkarni-Almeida A, Balachandran S, Balakrishnan A, Vishwakarma RA. Bharate SB, et al. Among authors: balachandran s. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6357-61. doi: 10.1016/j.bmcl.2008.10.085. Epub 2008 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18993064
Novel derivatives of ISO-1 as potent inhibitors of MIF biological function.
Balachandran S, Rodge A, Gadekar PK, Yadav VN, Kamath D, Chetrapal-Kunwar A, Bhatt P, Srinivasan S, Sharma S, Vishwakarma RA, Dagia NM. Balachandran S, et al. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4773-6. doi: 10.1016/j.bmcl.2009.06.052. Epub 2009 Jun 17. Bioorg Med Chem Lett. 2009. PMID: 19592246
Synthesis and biological activity of novel MIF antagonists.
Balachandran S, Gadekar PK, Parkale S, Yadav VN, Kamath D, Ramaswamy S, Sharma S, Vishwakarma RA, Dagia NM. Balachandran S, et al. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1508-11. doi: 10.1016/j.bmcl.2010.12.127. Epub 2011 Jan 1. Bioorg Med Chem Lett. 2011. PMID: 21277206
A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis.
Dagia NM, Kamath DV, Bhatt P, Gupte RD, Dadarkar SS, Fonseca L, Agarwal G, Chetrapal-Kunwar A, Balachandran S, Srinivasan S, Bose J, Pari K, B-Rao C, Parkale SS, Gadekar PK, Rodge AH, Mandrekar N, Vishwakarma RA, Sharma S. Dagia NM, et al. Among authors: balachandran s. Eur J Pharmacol. 2009 Apr 1;607(1-3):201-12. doi: 10.1016/j.ejphar.2009.02.031. Epub 2009 Feb 21. Eur J Pharmacol. 2009. PMID: 19239912
Pharmacology of a novel, orally active PDE4 inhibitor.
Dastidar SG, Ray A, Shirumalla R, Rajagopal D, Chaudhary S, Nanda K, Sharma P, Seth MK, Balachandran S, Gupta N, Palle V. Dastidar SG, et al. Among authors: balachandran s. Pharmacology. 2009;83(5):275-86. doi: 10.1159/000209608. Epub 2009 Mar 25. Pharmacology. 2009. PMID: 19321962
Necroptosis blockade prevents lung injury in severe influenza.
Gautam A, Boyd DF, Nikhar S, Zhang T, Siokas I, Van de Velde LA, Gaevert J, Meliopoulos V, Thapa B, Rodriguez DA, Cai KQ, Yin C, Schnepf D, Beer J, DeAntoneo C, Williams RM, Shubina M, Livingston B, Zhang D, Andrake MD, Lee S, Boda R, Duddupudi AL, Crawford JC, Vogel P, Loch C, Schwemmle M, Fritz LC, Schultz-Cherry S, Green DR, Cuny GD, Thomas PG, Degterev A, Balachandran S. Gautam A, et al. Among authors: balachandran s. Nature. 2024 Apr;628(8009):835-843. doi: 10.1038/s41586-024-07265-8. Epub 2024 Apr 10. Nature. 2024. PMID: 38600381
STIGMA: Single-cell tissue-specific gene prioritization using machine learning.
Balachandran S, Prada-Medina CA, Mensah MA, Glaser J, Kakar N, Nagel I, Pozojevic J, Audain E, Hitz MP, Kircher M, Sreenivasan VKA, Spielmann M. Balachandran S, et al. Am J Hum Genet. 2024 Mar 7;111(3):618. doi: 10.1016/j.ajhg.2024.01.009. Am J Hum Genet. 2024. PMID: 38458167 Free PMC article. No abstract available.
MRE11 mobilizes CGAS and drives ZBP1-dependent necroptosis.
Beltrán-Visiedo M, Balachandran S, Galluzzi L. Beltrán-Visiedo M, et al. Among authors: balachandran s. Cell Res. 2024 Mar 5. doi: 10.1038/s41422-024-00939-y. Online ahead of print. Cell Res. 2024. PMID: 38443562 No abstract available.
STIGMA: Single-cell tissue-specific gene prioritization using machine learning.
Balachandran S, Prada-Medina CA, Mensah MA, Kakar N, Nagel I, Pozojevic J, Audain E, Hitz MP, Kircher M, Sreenivasan VKA, Spielmann M. Balachandran S, et al. Am J Hum Genet. 2024 Feb 1;111(2):338-349. doi: 10.1016/j.ajhg.2023.12.011. Epub 2024 Jan 15. Am J Hum Genet. 2024. PMID: 38228144 Free PMC article.
363 results