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Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome.
Stackowicz J, Gaudenzio N, Serhan N, Conde E, Godon O, Marichal T, Starkl P, Balbino B, Roers A, Bruhns P, Jönsson F, Moguelet P, Georgin-Lavialle S, Broderick L, Hoffman HM, Galli SJ, Reber LL. Stackowicz J, et al. Among authors: balbino b. J Exp Med. 2021 Oct 4;218(10):e20201466. doi: 10.1084/jem.20201466. Epub 2021 Sep 3. J Exp Med. 2021. PMID: 34477811 Free PMC article.
Approaches to target IgE antibodies in allergic diseases.
Balbino B, Conde E, Marichal T, Starkl P, Reber LL. Balbino B, et al. Pharmacol Ther. 2018 Nov;191:50-64. doi: 10.1016/j.pharmthera.2018.05.015. Epub 2018 Jun 27. Pharmacol Ther. 2018. PMID: 29909239 Free article. Review.
Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice.
Conde E, Bertrand R, Balbino B, Bonnefoy J, Stackowicz J, Caillot N, Colaone F, Hamdi S, Houmadi R, Loste A, Kamphuis JBJ, Huetz F, Guilleminault L, Gaudenzio N, Mougel A, Hardy D, Snouwaert JN, Koller BH, Serra V, Bruhns P, Grouard-Vogel G, Reber LL. Conde E, et al. Among authors: balbino b. Nat Commun. 2021 May 11;12(1):2574. doi: 10.1038/s41467-021-22834-5. Nat Commun. 2021. PMID: 33976140 Free PMC article.
IgE in the pathophysiology and therapy of food allergy.
Michelet M, Balbino B, Guilleminault L, Reber LL. Michelet M, et al. Among authors: balbino b. Eur J Immunol. 2021 Mar;51(3):531-543. doi: 10.1002/eji.202048833. Epub 2021 Feb 17. Eur J Immunol. 2021. PMID: 33527384 Free article. Review.
The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors.
Balbino B, Herviou P, Godon O, Stackowicz J, Goff OR, Iannascoli B, Sterlin D, Brûlé S, Millot GA, Harris FM, Voronina VA, Nadeau KC, Macdonald LE, Murphy AJ, Bruhns P, Reber LL. Balbino B, et al. J Clin Invest. 2020 Mar 2;130(3):1330-1335. doi: 10.1172/JCI129697. J Clin Invest. 2020. PMID: 31770111 Free PMC article.
IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.
Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G. Lee CH, et al. Among authors: balbino b. Nat Immunol. 2017 Aug;18(8):889-898. doi: 10.1038/ni.3770. Epub 2017 Jun 12. Nat Immunol. 2017. PMID: 28604720 Free PMC article.
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