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Lymphangiogenesis and cancer metastasis.
Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K. Stacker SA, et al. Nat Rev Cancer. 2002 Aug;2(8):573-83. doi: 10.1038/nrc863. Nat Rev Cancer. 2002. PMID: 12154350 Review.
Corneal avascularity is due to soluble VEGF receptor-1.
Ambati BK, Nozaki M, Singh N, Takeda A, Jani PD, Suthar T, Albuquerque RJ, Richter E, Sakurai E, Newcomb MT, Kleinman ME, Caldwell RB, Lin Q, Ogura Y, Orecchia A, Samuelson DA, Agnew DW, St Leger J, Green WR, Mahasreshti PJ, Curiel DT, Kwan D, Marsh H, Ikeda S, Leiper LJ, Collinson JM, Bogdanovich S, Khurana TS, Shibuya M, Baldwin ME, Ferrara N, Gerber HP, De Falco S, Witta J, Baffi JZ, Raisler BJ, Ambati J. Ambati BK, et al. Nature. 2006 Oct 26;443(7114):993-7. doi: 10.1038/nature05249. Epub 2006 Oct 18. Nature. 2006. PMID: 17051153 Free PMC article.
Differential expression of VEGF ligands and receptors in prostate cancer.
Woollard DJ, Opeskin K, Coso S, Wu D, Baldwin ME, Williams ED. Woollard DJ, et al. Prostate. 2013 May;73(6):563-72. doi: 10.1002/pros.22596. Epub 2012 Oct 4. Prostate. 2013. PMID: 23038639
VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium.
Karnezis T, Shayan R, Caesar C, Roufail S, Harris NC, Ardipradja K, Zhang YF, Williams SP, Farnsworth RH, Chai MG, Rupasinghe TW, Tull DL, Baldwin ME, Sloan EK, Fox SB, Achen MG, Stacker SA. Karnezis T, et al. Cancer Cell. 2012 Feb 14;21(2):181-95. doi: 10.1016/j.ccr.2011.12.026. Cancer Cell. 2012. PMID: 22340592
Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos.
Haiko P, Makinen T, Keskitalo S, Taipale J, Karkkainen MJ, Baldwin ME, Stacker SA, Achen MG, Alitalo K. Haiko P, et al. Mol Cell Biol. 2008 Aug;28(15):4843-50. doi: 10.1128/MCB.02214-07. Epub 2008 Jun 2. Mol Cell Biol. 2008. PMID: 18519586 Free PMC article.
Molecular pathways for lymphangiogenesis and their role in human disease.
Stacker SA, Farnsworth RH, Karnezis T, Shayan R, Smith DP, Paavonen K, Davydova N, Caesar C, Inder R, Baldwin ME, McColl BK, Roufail S, Williams RA, Hughes RA, Alitalo K, Achen MG. Stacker SA, et al. Novartis Found Symp. 2007;281:38-43; discussion 44-53, 208-9. doi: 10.1002/9780470062128.ch4. Novartis Found Symp. 2007. PMID: 17534064 Review.
Vascular endothelial growth factor D is dispensable for development of the lymphatic system.
Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG. Baldwin ME, et al. Mol Cell Biol. 2005 Mar;25(6):2441-9. doi: 10.1128/MCB.25.6.2441-2449.2005. Mol Cell Biol. 2005. PMID: 15743836 Free PMC article.
Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer.
Zeng Y, Opeskin K, Baldwin ME, Horvath LG, Achen MG, Stacker SA, Sutherland RL, Williams ED. Zeng Y, et al. Clin Cancer Res. 2004 Aug 1;10(15):5137-44. doi: 10.1158/1078-0432.CCR-03-0434. Clin Cancer Res. 2004. PMID: 15297417
Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D.
McColl BK, Baldwin ME, Roufail S, Freeman C, Moritz RL, Simpson RJ, Alitalo K, Stacker SA, Achen MG. McColl BK, et al. J Exp Med. 2003 Sep 15;198(6):863-8. doi: 10.1084/jem.20030361. Epub 2003 Sep 8. J Exp Med. 2003. PMID: 12963694 Free PMC article.
Regenerating lizard tails: a new model for investigating lymphangiogenesis.
Daniels CB, Lewis BC, Tsopelas C, Munns SL, Orgeig S, Baldwin ME, Stacker SA, Achen MG, Chatterton BE, Cooter RD. Daniels CB, et al. FASEB J. 2003 Mar;17(3):479-81. doi: 10.1096/fj.02-0579fje. Epub 2003 Jan 2. FASEB J. 2003. PMID: 12514111
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