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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 5
1982 1
1988 2
1989 2
1990 1
1991 3
1992 2
1993 6
1994 3
1995 3
1996 9
1997 10
1998 3
1999 10
2000 2
2001 10
2002 8
2003 6
2004 7
2005 7
2006 9
2007 9
2008 11
2009 11
2010 6
2011 5
2012 7
2013 8
2014 15
2015 10
2016 8
2017 15
2018 11
2019 10
2020 6
2021 11
2022 9
2023 6
2024 9
2025 12
2026 0

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267 results

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Page 1
Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate cancer.
Westaby D, Jiménez-Vacas JM, Figueiredo I, Welti J, Gurel B, Bogdan D, Buroni L, Neeb AJ, Rekowski J, Padilha A, Das S, Taylor J, Zeng W, Waldron N, Goldsmith T, Hobern E, Gabel F, Pandell N, Miranda S, Lambros MB, Carreira S, Swain A, Yuan W, Balk SP, Bezzi M, de Bono JS, Sharp A. Westaby D, et al. Among authors: balk sp. iScience. 2025 Nov 10;28(12):113985. doi: 10.1016/j.isci.2025.113985. eCollection 2025 Dec 19. iScience. 2025. PMID: 41438049 Free PMC article.
Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion.
Ma F, Chen S, Cecchi L, Ersoy-Fazlioglu B, Russo JW, Arai S, Awad S, Calagua C, Xie F, Poluben L, Voznesensky O, Ku AT, Karzai F, Cai C, Einstein DJ, Ye H, Yuan X, Toker A, Taplin ME, Sowalsky AG, Balk SP. Ma F, et al. Among authors: balk sp. J Clin Invest. 2025 Oct 2;135(23):e192368. doi: 10.1172/JCI192368. eCollection 2025 Dec 1. J Clin Invest. 2025. PMID: 41321318 Free PMC article.
Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer.
Jiménez-Vacas JM, Westaby D, Figueiredo I, De Haven Brandon A, Padilha A, Yuan W, Seed G, Bogdan D, Gurel B, Bertan C, Miranda S, Lambros M, Montero-Hidalgo AJ, Coleman I, Yu IPL, Buroni L, Zeng W, Neeb AJ, Welti J, Rekowski J, Paravati R, Gabel F, Pandell N, Ferreira A, Crespo M, Riisnaes R, Das S, Taylor J, Waldron N, Hobern E, Valenti M, Ning J, Bernett I, Liodaki K, Persse T, Galipeau P, Wilkinson S, Trostel SY, Karzai F, Chau CH, Beatson EL, Zhang X, Klumpp-Thomas C, Varkaris A, Luque RM, Swain A, Raynaud F, Lack NA, Thomas CJ, Ha G, Figg WD, Bezzi M, Sowalsky AG, Nelson PS, Carreira S, Balk SP, de Bono JS, Sharp A. Jiménez-Vacas JM, et al. Among authors: balk sp. Nat Commun. 2025 Oct 8;16(1):8806. doi: 10.1038/s41467-025-64042-5. Nat Commun. 2025. PMID: 41062500 Free PMC article.
Increased ErbB2 Signaling Is an Early Adaptation to Androgen Signaling Inhibition and Persists in Castration-Resistant Prostate Cancer.
Owiredu J, Ersoy-Fazlioglu B, Poluben L, Calagua C, Dennehy C, Stavridi AM, Wang L, Voznesensky O, Xie F, Ye H, Sun Y, Einstein DJ, Gao X, Mantia C, Taplin ME, Muller WJ, Balk SP, Russo JW. Owiredu J, et al. Among authors: balk sp. Clin Cancer Res. 2025 Nov 3;31(21):4598-4610. doi: 10.1158/1078-0432.CCR-22-3683. Clin Cancer Res. 2025. PMID: 40795068 Free PMC article.
BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways.
Hirani R, Nandakumar S, Zaman N, Prabhakaraalva P, King SA, Kalidindi TM, Ghale R, Rajanala SH, Fidele DC, De Stanchina E, Mary Lee GS, Taplin ME, Balk SP, Sowalsky AG, Morris MJ, Kishore Pillarsetty NV, Stopsack KH, Gopalan A, Mucci LA, Kyprianou N, Tewari AK, Danila D, Kantoff PW, Chakraborty G. Hirani R, et al. Among authors: balk sp. Cell Rep. 2025 Jun 24;44(6):115779. doi: 10.1016/j.celrep.2025.115779. Epub 2025 May 30. Cell Rep. 2025. PMID: 40448998 Free PMC article.
BH3 mimetics targeting BCL-XL have efficacy in solid tumors with RB1 loss and replication stress.
Varkaris A, Wang K, Nouri M, Kozlova N, Schmidt DR, Stavridi A, Arai S, Ambrosio N, Poluben L, Jimenez-Vacas JM, Westaby D, Carmichael J, Xie F, Figueiredo I, Buroni L, Neeb A, Gurel B, Chevalier N, Brown L, Voznesensky O, Chen SY, Russo JW, Yuan X, Juric D, Beltran H, De Bono JS, Vander Heiden MG, Einstein DJ, Muranen T, Corey E, Sharp A, Balk SP. Varkaris A, et al. Among authors: balk sp. Nat Commun. 2025 May 28;16(1):4931. doi: 10.1038/s41467-025-60238-x. Nat Commun. 2025. PMID: 40436896 Free PMC article.
267 results