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Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.
Vander Haar E, Lee SI, Bandhakavi S, Griffin TJ, Kim DH. Vander Haar E, et al. Among authors: Bandhakavi S. Nat Cell Biol. 2007 Mar;9(3):316-23. doi: 10.1038/ncb1547. Epub 2007 Feb 4. Nat Cell Biol. 2007. PMID: 17277771
Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis.
Bandhakavi S, Xie H, O'Callaghan B, Sakurai H, Kim DH, Griffin TJ. Bandhakavi S, et al. PLoS One. 2008 Feb 13;3(2):e1598. doi: 10.1371/journal.pone.0001598. PLoS One. 2008. PMID: 18270585 Free PMC article.
Specifically, we hypothesized that activation of regulator(s) of heat/oxidative stress responses phenocopied TOR inhibition and sought to identify these putative TOR inhibitor(s). ...Thus, we propose that activated Hsf1 inhibits rapamycin resistance and TOR signaling via elevated expression of specific target genes in S. cerevisiae. ...
Specifically, we hypothesized that activation of regulator(s) of heat/oxidative stress responses phenocopied TOR inhibition and sough …
PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
Woo SY, Kim DH, Jun CB, Kim YM, Haar EV, Lee SI, Hegg JW, Bandhakavi S, Griffin TJ, Kim DH. Woo SY, et al. Among authors: Bandhakavi S. J Biol Chem. 2007 Aug 31;282(35):25604-12. doi: 10.1074/jbc.M704343200. Epub 2007 Jun 28. J Biol Chem. 2007. PMID: 17599906
., Castellvi-Bel, S., Chang, L. M., Sung, R. K., Bowser, M. J., Pique, J. M., Castells, A., and Rustgi, A. K. (2005) Genomics 85, 338-351). ...
., Castellvi-Bel, S., Chang, L. M., Sung, R. K., Bowser, M. J., Pique, J. M., Castells, A., and Rustgi, A. K. (2005) Genomics 85, 338 …
Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response.
Bandhakavi S, Kim YM, Ro SH, Xie H, Onsongo G, Jun CB, Kim DH, Griffin TJ. Bandhakavi S, et al. Mol Cell Proteomics. 2010 Feb;9(2):403-14. doi: 10.1074/mcp.M900326-MCP200. Epub 2009 Nov 23. Mol Cell Proteomics. 2010. PMID: 19955088 Free PMC article.
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