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The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance.
Banerjee A, Sugantino M, Sacchettini JC, Jacobs WR Jr. Banerjee A, et al. Microbiology. 1998 Oct;144 ( Pt 10):2697-704. doi: 10.1099/00221287-144-10-2697. Microbiology. 1998. PMID: 9802011
A target of the anti-tuberculosis drugs isoniazid (INH) and ethionamide (ETH) has been shown to be an enoyl reductase, encoded by the inhA gene. ...In M. smegmatis, inhA and mabA are independently transcribed, but in M. tuberculosis and M. bovis BCG, mabA and inhA constitu
A target of the anti-tuberculosis drugs isoniazid (INH) and ethionamide (ETH) has been shown to be an enoyl reductase, encoded by the
Genetic determination of the meso-diaminopimelate biosynthetic pathway of mycobacteria.
Cirillo JD, Weisbrod TR, Banerjee A, Bloom BR, Jacobs WR Jr. Cirillo JD, et al. J Bacteriol. 1994 Jul;176(14):4424-9. doi: 10.1128/jb.176.14.4424-4429.1994. J Bacteriol. 1994. PMID: 8021227 Free PMC article. Retracted.
The increasing incidence of multiple-drug-resistant mycobacterial infections indicates that the development of new methods for treatment of mycobacterial diseases should be a high priority. meso-Diaminopimelic acid (DAP), a key component of a highly immunogen …
The increasing incidence of multiple-drug-resistant mycobacterial infections indicates that the development of new methods for treatment of …
Comparison of the CopB systems of plasmids R1 and ColV2-K94: a single base alteration in CopB gene is responsible for the increased copy number of the low copy number plasmid ColV2-K94.
Banerjee A, Weber PC, Palchaudhuri S. Banerjee A, et al. Mol Gen Genet. 1990 Jan;220(2):320-4. doi: 10.1007/BF00260502. Mol Gen Genet. 1990. PMID: 2325626
We have isolated a deletion mutation and a point mutation in the copB gene of the replication region Repl of the IncFI plasmid ColV2-K94. Subsequently, this copB gene with and without point mutation was cloned and sequenced, and the point mutation was mapped in the …
We have isolated a deletion mutation and a point mutation in the copB gene of the replication region Repl of the IncFI plasmid …
inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis.
Banerjee A, Dubnau E, Quemard A, Balasubramanian V, Um KS, Wilson T, Collins D, de Lisle G, Jacobs WR Jr. Banerjee A, et al. Science. 1994 Jan 14;263(5144):227-30. doi: 10.1126/science.8284673. Science. 1994. PMID: 8284673
The wild-type inhA gene also conferred INH and ETH resistance when transferred on a multicopy plasmid vector to M. smegmatis and M. bovis BCG. ...These results suggest that InhA is likely a primary target of action for INH and ETH....
The wild-type inhA gene also conferred INH and ETH resistance when transferred on a multicopy plasmid vector to M. smegmatis and M. b …
Rapid Mycobacterium species assignment and unambiguous identification of mutations associated with antimicrobial resistance in Mycobacterium tuberculosis by automated DNA sequencing.
Kapur V, Li LL, Hamrick MR, Plikaytis BB, Shinnick TM, Telenti A, Jacobs WR Jr, Banerjee A, Cole S, Yuen KY, et al. Kapur V, et al. Arch Pathol Lab Med. 1995 Feb;119(2):131-8. Arch Pathol Lab Med. 1995. PMID: 7848059
DESIGN AND SPECIMENS: A 360-base pair segment of the gene (hsp65) encoding a 65-kd heat shock protein was characterized from 91 isolates assigned to 24 Mycobacterium species by traditional biochemical techniques. ...CONCLUSIONS: Rapid identification of M tuberculosi …
DESIGN AND SPECIMENS: A 360-base pair segment of the gene (hsp65) encoding a 65-kd heat shock protein was characterized from 9 …
Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study.
Heym B, Honoré N, Truffot-Pernot C, Banerjee A, Schurra C, Jacobs WR Jr, van Embden JD, Grosset JH, Cole ST. Heym B, et al. Lancet. 1994 Jul 30;344(8918):293-8. doi: 10.1016/s0140-6736(94)91338-2. Lancet. 1994. PMID: 7914261
A further 5 strains had alterations in the inhA locus without the katG gene being mutated. Rifampicin resistance was less frequent (13 strains) and usually associated with isoniazid resistance (11 of 13 strains). ...Thus, multidrug resistance is not due to a novel m
A further 5 strains had alterations in the inhA locus without the katG gene being mutated. Rifampicin resistance was less frequent (1
Cloning and DNA sequence of plasmid determinant iss, coding for increased serum survival and surface exclusion, which has homology with lambda DNA.
Chuba PJ, Leon MA, Banerjee A, Palchaudhuri S. Chuba PJ, et al. Mol Gen Genet. 1989 Apr;216(2-3):287-92. doi: 10.1007/BF00334367. Mol Gen Genet. 1989. PMID: 2546040
Escherichia coli K12 cells carrying a cloned 1.4 kb HindIII fragment from plasmid ColV2-K94, showed increased survival in guinea pig serum. ...Determination of the DNA sequence of the fragment demonstrated the presence of a truncated IS2 (165 bp), separated by 250 b …
Escherichia coli K12 cells carrying a cloned 1.4 kb HindIII fragment from plasmid ColV2-K94, showed increased survival in guinea pig …
Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for Rif(R), Toxicity, Mutagenicity, Plasmid Curing.
Hayes S, Wang W, Rajamanickam K, Chu A, Banerjee A, Hayes C. Hayes S, et al. Viruses. 2016 Jun 22;8(6):172. doi: 10.3390/v8060172. Viruses. 2016. PMID: 27338450 Free PMC article.
The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due to the formation of a dead-end P-DnaB complex, sequestering the replicative DnaB helicase from further activity. ...Using fluctuation …
The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due …
Land masses and oceanic currents drive population structure of Heritiera littoralis, a widespread mangrove in the Indo-West Pacific.
Banerjee AK, Guo W, Qiao S, Li W, Xing F, Lin Y, Hou Z, Li S, Liu Y, Huang Y. Banerjee AK, et al. Ecol Evol. 2020 Jun 3;10(14):7349-7363. doi: 10.1002/ece3.6460. eCollection 2020 Jul. Ecol Evol. 2020. PMID: 32760533 Free PMC article.
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