Bao G - Search Results

1

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites.

Cradick TJ, Qiu P, Lee CM, Fine EJ, Bao G. Cradick TJ, et al. Among authors: bao g. Mol Ther Nucleic Acids. 2014 Dec 2;3(12):e214. doi: 10.1038/mtna.2014.64. Mol Ther Nucleic Acids. 2014. PMID: 25462530 Free PMC article.

2

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity.

Cradick TJ, Fine EJ, Antico CJ, Bao G. Cradick TJ, et al. Among authors: bao g. Nucleic Acids Res. 2013 Nov;41(20):9584-92. doi: 10.1093/nar/gkt714. Epub 2013 Aug 11. Nucleic Acids Res. 2013. PMID: 23939622 Free PMC article.

3

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage.

Fine EJ, Cradick TJ, Zhao CL, Lin Y, Bao G. Fine EJ, et al. Among authors: bao g. Nucleic Acids Res. 2014 Apr;42(6):e42. doi: 10.1093/nar/gkt1326. Epub 2013 Dec 30. Nucleic Acids Res. 2014. PMID: 24381193 Free PMC article.

4

SAPTA: a new design tool for improving TALE nuclease activity.

Lin Y, Fine EJ, Zheng Z, Antico CJ, Voit RA, Porteus MH, Cradick TJ, Bao G. Lin Y, et al. Among authors: bao g. Nucleic Acids Res. 2014 Apr;42(6):e47. doi: 10.1093/nar/gkt1363. Epub 2014 Jan 16. Nucleic Acids Res. 2014. PMID: 24442582 Free PMC article.

5

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.

Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G. Lin Y, et al. Among authors: bao g. Nucleic Acids Res. 2014 Jun;42(11):7473-85. doi: 10.1093/nar/gku402. Epub 2014 May 16. Nucleic Acids Res. 2014. PMID: 24838573 Free PMC article.

6

The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.

Lee CM, Cradick TJ, Bao G. Lee CM, et al. Among authors: bao g. Mol Ther. 2016 Mar;24(3):645-54. doi: 10.1038/mt.2016.8. Epub 2016 Jan 19. Mol Ther. 2016. PMID: 26782639 Free PMC article.

7

Nanomedicine: tiny particles and machines give huge gains.

Tong S, Fine EJ, Lin Y, Cradick TJ, Bao G. Tong S, et al. Among authors: bao g. Ann Biomed Eng. 2014 Feb;42(2):243-59. doi: 10.1007/s10439-013-0952-x. Epub 2013 Dec 3. Ann Biomed Eng. 2014. PMID: 24297494 Free PMC article. Review.

8

Designing and testing the activities of TAL effector nucleases.

Lin Y, Cradick TJ, Bao G. Lin Y, et al. Among authors: bao g. Methods Mol Biol. 2014;1114:203-19. doi: 10.1007/978-1-62703-761-7_13. Methods Mol Biol. 2014. PMID: 24557905

9

High-throughput cellular screening of engineered nuclease activity using the single-strand annealing assay and luciferase reporter.

Cradick TJ, Antico CJ, Bao G. Cradick TJ, et al. Among authors: bao g. Methods Mol Biol. 2014;1114:339-52. doi: 10.1007/978-1-62703-761-7_22. Methods Mol Biol. 2014. PMID: 24557914

10

Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models.

Fine EJ, Cradick TJ, Bao G. Fine EJ, et al. Among authors: bao g. Methods Mol Biol. 2014;1114:371-83. doi: 10.1007/978-1-62703-761-7_24. Methods Mol Biol. 2014. PMID: 24557916

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