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Caspase 2 is both required for p53-mediated apoptosis and downregulated by p53 in a p21-dependent manner.
Baptiste-Okoh N, Barsotti AM, Prives C. Baptiste-Okoh N, et al. Cell Cycle. 2008 May 1;7(9):1133-8. doi: 10.4161/cc.7.9.5805. Epub 2008 Feb 19. Cell Cycle. 2008. PMID: 18418048
A role for caspase 2 and PIDD in the process of p53-mediated apoptosis.
Baptiste-Okoh N, Barsotti AM, Prives C. Baptiste-Okoh N, et al. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1937-42. doi: 10.1073/pnas.0711800105. Epub 2008 Jan 31. Proc Natl Acad Sci U S A. 2008. PMID: 18238895 Free PMC article.
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