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Page 1
Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors.
Yeh BJ, Rutigliano RJ, Deb A, Bar-Sagi D, Lim WA. Yeh BJ, et al. Nature. 2007 May 31;447(7144):596-600. doi: 10.1038/nature05851. Epub 2007 May 21. Nature. 2007. PMID: 17515921
Co-capping of ras proteins with surface immunoglobulins in B lymphocytes.
Graziadei L, Riabowol K, Bar-Sagi D. Graziadei L, et al. Nature. 1990 Sep 27;347(6291):396-400. doi: 10.1038/347396a0. Nature. 1990. PMID: 2120590
Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.
Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D. Gale NW, et al. Nature. 1993 May 6;363(6424):88-92. doi: 10.1038/363088a0. Nature. 1993. PMID: 8386805
Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J. Li N, et al. Nature. 1993 May 6;363(6424):85-8. doi: 10.1038/363085a0. Nature. 1993. PMID: 8479541
The structural basis of the activation of Ras by Sos.
Boriack-Sjodin PA, Margarit SM, Bar-Sagi D, Kuriyan J. Boriack-Sjodin PA, et al. Nature. 1998 Jul 23;394(6691):337-43. doi: 10.1038/28548. Nature. 1998. PMID: 9690470
Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange.
Hall BE, Yang SS, Boriack-Sjodin PA, Kuriyan J, Bar-Sagi D. Hall BE, et al. J Biol Chem. 2001 Jul 20;276(29):27629-37. doi: 10.1074/jbc.M101727200. Epub 2001 May 1. J Biol Chem. 2001. PMID: 11333268
Redox-dependent downregulation of Rho by Rac.
Nimnual AS, Taylor LJ, Bar-Sagi D. Nimnual AS, et al. Nat Cell Biol. 2003 Mar;5(3):236-41. doi: 10.1038/ncb938. Nat Cell Biol. 2003. PMID: 12598902
Modulation of signalling by Sprouty: a developing story.
Kim HJ, Bar-Sagi D. Kim HJ, et al. Nat Rev Mol Cell Biol. 2004 Jun;5(6):441-50. doi: 10.1038/nrm1400. Nat Rev Mol Cell Biol. 2004. PMID: 15173823 Review. No abstract available.
Analysis of Ras:RasGEF interactions by phage display and static multi-angle light scattering.
Sondermann H, Zhao C, Bar-Sagi D. Sondermann H, et al. Methods. 2005 Oct;37(2):197-202. doi: 10.1016/j.ymeth.2005.05.016. Methods. 2005. PMID: 16288886
Spatial regulation of EGFR signaling by Sprouty2.
Kim HJ, Taylor LJ, Bar-Sagi D. Kim HJ, et al. Curr Biol. 2007 Mar 6;17(5):455-61. doi: 10.1016/j.cub.2007.01.059. Epub 2007 Feb 22. Curr Biol. 2007. PMID: 17320394