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Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications.

Baraldi PG, Preti D, Borea PA, Varani K. Baraldi PG, et al. J Med Chem. 2012 Jun 28;55(12):5676-703. doi: 10.1021/jm300087j. Epub 2012 Apr 17. J Med Chem. 2012. PMID: 22468757 Review. No abstract available.

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Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds.

Romagnoli R, Baraldi PG, Prencipe F, Balzarini J, Liekens S, Estévez F. Romagnoli R, et al. Among authors: baraldi pg. Eur J Med Chem. 2015 Aug 28;101:205-17. doi: 10.1016/j.ejmech.2015.06.042. Epub 2015 Jun 25. Eur J Med Chem. 2015. PMID: 26141911

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Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.

Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Bertolasi V, Cancellieri M, Brancale A, Hamel E, Castagliuolo I, Consolaro F, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: baraldi pg. J Med Chem. 2014 Aug 14;57(15):6795-808. doi: 10.1021/jm5008193. Epub 2014 Jul 28. J Med Chem. 2014. PMID: 25025853 Free PMC article.

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Design, synthesis and biological evaluation of arylcinnamide hybrid derivatives as novel anticancer agents.

Romagnoli R, Baraldi PG, Salvador MK, Chayah M, Camacho ME, Prencipe F, Hamel E, Consolaro F, Basso G, Viola G. Romagnoli R, et al. Among authors: baraldi pg. Eur J Med Chem. 2014 Jun 23;81:394-407. doi: 10.1016/j.ejmech.2014.05.028. Epub 2014 May 10. Eur J Med Chem. 2014. PMID: 24858544 Free PMC article.

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Anticancer activity of novel hybrid molecules containing 5-benzylidene thiazolidine-2,4-dione.

Romagnoli R, Baraldi PG, Salvador MK, Camacho ME, Balzarini J, Bermejo J, Estévez F. Romagnoli R, et al. Among authors: baraldi pg. Eur J Med Chem. 2013 May;63:544-57. doi: 10.1016/j.ejmech.2013.02.030. Epub 2013 Mar 14. Eur J Med Chem. 2013. PMID: 23537942

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Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives.

Romagnoli R, Baraldi PG, Cruz-Lopez O, Tolomeo M, Di Cristina A, Pipitone RM, Grimaudo S, Balzarini J, Brancale A, Hamel E. Romagnoli R, et al. Among authors: baraldi pg. Bioorg Med Chem Lett. 2011 May 1;21(9):2746-51. doi: 10.1016/j.bmcl.2010.11.083. Epub 2010 Nov 21. Bioorg Med Chem Lett. 2011. PMID: 21146985 Free PMC article.

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Synthesis and cellular pharmacology studies of a series of 2-amino-3-aroyl-4-substituted thiophene derivatives.

Romagnoli R, Baraldi PG, Pavani MG, Cruz-Lopez O, Hamel E, Balzarini J, Brognara E, Zuccato C, Gambari R. Romagnoli R, et al. Among authors: baraldi pg. Med Chem. 2010 Nov;6(6):329-43. doi: 10.2174/157340610793563974. Med Chem. 2010. PMID: 21054275

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Substituted 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors.

Romagnoli R, Baraldi PG, Carrion MD, Cruz-Lopez O, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Brancale A, Hamel E. Romagnoli R, et al. Among authors: baraldi pg. Bioorg Med Chem. 2010 Jul 15;18(14):5114-22. doi: 10.1016/j.bmc.2010.05.068. Epub 2010 Jun 1. Bioorg Med Chem. 2010. PMID: 20579891 Free PMC article.

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Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.

Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez Cara C, Carrion MD, Brancale A, Hamel E, Chen L, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: baraldi pg. J Med Chem. 2010 May 27;53(10):4248-58. doi: 10.1021/jm100245q. J Med Chem. 2010. PMID: 20420439 Free PMC article.

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Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.

Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez Cara C, Carrion MD, Balzarini J, Hamel E, Basso G, Bortolozzi R, Viola G. Romagnoli R, et al. Among authors: baraldi pg. Bioorg Med Chem Lett. 2010 May 1;20(9):2733-9. doi: 10.1016/j.bmcl.2010.03.075. Epub 2010 Mar 25. Bioorg Med Chem Lett. 2010. PMID: 20378350 Free PMC article.

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