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The role of placental exosomes in reproduction.
Mincheva-Nilsson L, Baranov V. Mincheva-Nilsson L, et al. Am J Reprod Immunol. 2010 Jun;63(6):520-33. doi: 10.1111/j.1600-0897.2010.00822.x. Epub 2010 Mar 11. Am J Reprod Immunol. 2010. PMID: 20331583 Review.
Human placenta expresses and secretes NKG2D ligands via exosomes that down-modulate the cognate receptor expression: evidence for immunosuppressive function.
Hedlund M, Stenqvist AC, Nagaeva O, Kjellberg L, Wulff M, Baranov V, Mincheva-Nilsson L. Hedlund M, et al. J Immunol. 2009 Jul 1;183(1):340-51. doi: 10.4049/jimmunol.0803477. J Immunol. 2009. PMID: 19542445
Exosomes secreted by human placenta carry functional Fas ligand and TRAIL molecules and convey apoptosis in activated immune cells, suggesting exosome-mediated immune privilege of the fetus.
Stenqvist AC, Nagaeva O, Baranov V, Mincheva-Nilsson L. Stenqvist AC, et al. J Immunol. 2013 Dec 1;191(11):5515-23. doi: 10.4049/jimmunol.1301885. Epub 2013 Nov 1. J Immunol. 2013. PMID: 24184557
Placenta-derived soluble MHC class I chain-related molecules down-regulate NKG2D receptor on peripheral blood mononuclear cells during human pregnancy: a possible novel immune escape mechanism for fetal survival.
Mincheva-Nilsson L, Nagaeva O, Chen T, Stendahl U, Antsiferova J, Mogren I, Hernestål J, Baranov V. Mincheva-Nilsson L, et al. J Immunol. 2006 Mar 15;176(6):3585-92. doi: 10.4049/jimmunol.176.6.3585. J Immunol. 2006. PMID: 16517727
An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells.
Golovliov I, Baranov V, Krocova Z, Kovarova H, Sjöstedt A. Golovliov I, et al. Infect Immun. 2003 Oct;71(10):5940-50. doi: 10.1128/iai.71.10.5940-5950.2003. Infect Immun. 2003. PMID: 14500514 Free PMC article.
Carcinoembryonic antigen (CEA) and CEA-related cell adhesion molecule 1 (CEACAM1), apically expressed on human colonic M cells, are potential receptors for microbial adhesion.
Baranov V, Hammarström S. Baranov V, et al. Histochem Cell Biol. 2004 Feb;121(2):83-9. doi: 10.1007/s00418-003-0613-5. Epub 2004 Jan 31. Histochem Cell Biol. 2004. PMID: 14758482
Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity.
Labani-Motlagh A, Israelsson P, Ottander U, Lundin E, Nagaev I, Nagaeva O, Dehlin E, Baranov V, Mincheva-Nilsson L. Labani-Motlagh A, et al. Tumour Biol. 2016 Apr;37(4):5455-66. doi: 10.1007/s13277-015-4313-2. Epub 2015 Nov 13. Tumour Biol. 2016. PMID: 26563374
Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion.
Lundholm M, Schröder M, Nagaeva O, Baranov V, Widmark A, Mincheva-Nilsson L, Wikström P. Lundholm M, et al. PLoS One. 2014 Sep 30;9(9):e108925. doi: 10.1371/journal.pone.0108925. eCollection 2014. PLoS One. 2014. PMID: 25268476 Free PMC article.
Placenta-derived exosomes and syncytiotrophoblast microparticles and their role in human reproduction: immune modulation for pregnancy success.
Mincheva-Nilsson L, Baranov V. Mincheva-Nilsson L, et al. Am J Reprod Immunol. 2014 Nov;72(5):440-57. doi: 10.1111/aji.12311. Epub 2014 Aug 28. Am J Reprod Immunol. 2014. PMID: 25164206
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