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Sex-dependent pain trajectories induced by prolactin require an inflammatory response for pain resolution.
Mecklenburg J, Wangzhou A, Hovhannisyan AH, Barba-Escobedo P, Shein SA, Zou Y, Weldon K, Lai Z, Goffin V, Dussor G, Tumanov AV, Price TJ, Akopian AN. Mecklenburg J, et al. Among authors: barba escobedo p. Brain Behav Immun. 2022 Mar;101:246-263. doi: 10.1016/j.bbi.2022.01.016. Epub 2022 Jan 19. Brain Behav Immun. 2022. PMID: 35065194 Free PMC article.
Prolactin Regulates Pain Responses via a Female-Selective Nociceptor-Specific Mechanism.
Patil M, Belugin S, Mecklenburg J, Wangzhou A, Paige C, Barba-Escobedo PA, Boyd JT, Goffin V, Grattan D, Boehm U, Dussor G, Price TJ, Akopian AN. Patil M, et al. Among authors: barba escobedo pa. iScience. 2019 Oct 25;20:449-465. doi: 10.1016/j.isci.2019.09.039. Epub 2019 Oct 1. iScience. 2019. PMID: 31627131 Free PMC article.
Pituitary hormones are specifically expressed in trigeminal sensory neurons and contribute to pain responses in the trigeminal system.
Hovhannisyan AH, Son H, Mecklenburg J, Barba-Escobedo PA, Tram M, Gomez R, Shannonhouse J, Zou Y, Weldon K, Ruparel S, Lai Z, Tumanov AV, Kim YS, Akopian AN. Hovhannisyan AH, et al. Among authors: barba escobedo pa. Sci Rep. 2021 Sep 8;11(1):17813. doi: 10.1038/s41598-021-97084-y. Sci Rep. 2021. PMID: 34497285 Free PMC article.