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What we have learned about pancreatic cancer from mouse models.
Pérez-Mancera PA, Guerra C, Barbacid M, Tuveson DA. Pérez-Mancera PA, et al. Among authors: barbacid m. Gastroenterology. 2012 May;142(5):1079-92. doi: 10.1053/j.gastro.2012.03.002. Epub 2012 Mar 8. Gastroenterology. 2012. PMID: 22406637 Review. No abstract available.
Mouse models of cancer.
Berns A, Barbacid M. Berns A, et al. Among authors: barbacid m. Mol Oncol. 2013 Apr;7(2):143-5. doi: 10.1016/j.molonc.2013.02.014. Epub 2013 Feb 26. Mol Oncol. 2013. PMID: 23499582 Free PMC article. No abstract available.
Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C. Hermann PC, et al. Among authors: barbacid m. Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12. Gastroenterology. 2014. PMID: 25127677
A Braf kinase-inactive mutant induces lung adenocarcinoma.
Nieto P, Ambrogio C, Esteban-Burgos L, Gómez-López G, Blasco MT, Yao Z, Marais R, Rosen N, Chiarle R, Pisano DG, Barbacid M, Santamaría D. Nieto P, et al. Among authors: barbacid m. Nature. 2017 Aug 10;548(7666):239-243. doi: 10.1038/nature23297. Epub 2017 Aug 2. Nature. 2017. PMID: 28783725 Free PMC article.
Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas.
Esteban-Burgos L, Wang H, Nieto P, Zheng J, Blanco-Aparicio C, Varela C, Gómez-López G, Fernández-García F, Sanclemente M, Guerra C, Drosten M, Galán J, Caleiras E, Martínez-Torrecuadrada J, Fajas L, Peng SB, Santamaría D, Musteanu M, Barbacid M. Esteban-Burgos L, et al. Among authors: barbacid m. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24415-24426. doi: 10.1073/pnas.2002520117. Epub 2020 Sep 10. Proc Natl Acad Sci U S A. 2020. PMID: 32913049 Free PMC article.
Reply: 'Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer'.
Alvarez R, Musteanu M, Garcia-Garcia E, Lopez-Casas PP, Megias D, Guerra C, Muñoz M, Quijano Y, Cubillo A, Rodriguez-Pascual J, Plaza C, de Vicente E, Prados S, Tabernero S, Barbacid M, Lopez-Rios F, Hidalgo M. Alvarez R, et al. Among authors: barbacid m. Br J Cancer. 2014 Oct 14;111(8):1677-8. doi: 10.1038/bjc.2014.129. Epub 2014 Mar 18. Br J Cancer. 2014. PMID: 24642623 Free PMC article. No abstract available.
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