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Vesicular stomatitis virus (VSV) therapy of tumors.
Balachandran S, Barber GN. Balachandran S, et al. Among authors: barber gn. IUBMB Life. 2000 Aug;50(2):135-8. doi: 10.1080/713803696. IUBMB Life. 2000. PMID: 11185959
Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth.
Meurs EF, Watanabe Y, Kadereit S, Barber GN, Katze MG, Chong K, Williams BR, Hovanessian AG. Meurs EF, et al. Among authors: barber gn. J Virol. 1992 Oct;66(10):5805-14. doi: 10.1128/JVI.66.10.5805-5814.1992. J Virol. 1992. PMID: 1382142 Free PMC article.
The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties.
Barber GN, Thompson S, Lee TG, Strom T, Jagus R, Darveau A, Katze MG. Barber GN, et al. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4278-82. doi: 10.1073/pnas.91.10.4278. Proc Natl Acad Sci U S A. 1994. PMID: 7514301 Free PMC article.
Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation.
Barber GN, Wambach M, Thompson S, Jagus R, Katze MG. Barber GN, et al. Mol Cell Biol. 1995 Jun;15(6):3138-46. doi: 10.1128/mcb.15.6.3138. Mol Cell Biol. 1995. PMID: 7539103 Free PMC article.
Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase.
Barber GN, Jagus R, Meurs EF, Hovanessian AG, Katze MG. Barber GN, et al. J Biol Chem. 1995 Jul 21;270(29):17423-8. doi: 10.1074/jbc.270.29.17423. J Biol Chem. 1995. PMID: 7615547
A novel translational regulation function for the simian virus 40 large-T antigen gene.
Rajan P, Swaminathan S, Zhu J, Cole CN, Barber G, Tevethia MJ, Thimmapaya B. Rajan P, et al. J Virol. 1995 Feb;69(2):785-95. doi: 10.1128/JVI.69.2.785-795.1995. J Virol. 1995. PMID: 7815544 Free PMC article.
Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase.
Barber GN, Wambach M, Wong ML, Dever TE, Hinnebusch AG, Katze MG. Barber GN, et al. Proc Natl Acad Sci U S A. 1993 May 15;90(10):4621-5. doi: 10.1073/pnas.90.10.4621. Proc Natl Acad Sci U S A. 1993. PMID: 8099444 Free PMC article.
The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity.
Polyak SJ, Tang N, Wambach M, Barber GN, Katze MG. Polyak SJ, et al. Among authors: barber gn. J Biol Chem. 1996 Jan 19;271(3):1702-7. doi: 10.1074/jbc.271.3.1702. J Biol Chem. 1996. PMID: 8576172
The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia.
Abraham N, Jaramillo ML, Duncan PI, M├ęthot N, Icely PL, Stojdl DF, Barber GN, Bell JC. Abraham N, et al. Among authors: barber gn. Exp Cell Res. 1998 Nov 1;244(2):394-404. doi: 10.1006/excr.1998.4201. Exp Cell Res. 1998. PMID: 9806790
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling.
Balachandran S, Kim CN, Yeh WC, Mak TW, Bhalla K, Barber GN. Balachandran S, et al. Among authors: barber gn. EMBO J. 1998 Dec 1;17(23):6888-902. doi: 10.1093/emboj/17.23.6888. EMBO J. 1998. PMID: 9843495 Free PMC article.
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