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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Ishikawa H, Barber GN. Ishikawa H, et al. Among authors: barber gn. Nature. 2008 Oct 2;455(7213):674-8. doi: 10.1038/nature07317. Epub 2008 Aug 24. Nature. 2008. PMID: 18724357 Free PMC article.
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway.
Balachandran S, Roberts PC, Kipperman T, Bhalla KN, Compans RW, Archer DR, Barber GN. Balachandran S, et al. Among authors: barber gn. J Virol. 2000 Feb;74(3):1513-23. doi: 10.1128/jvi.74.3.1513-1523.2000. J Virol. 2000. PMID: 10627563 Free PMC article.
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection.
Balachandran S, Roberts PC, Brown LE, Truong H, Pattnaik AK, Archer DR, Barber GN. Balachandran S, et al. Among authors: barber gn. Immunity. 2000 Jul;13(1):129-41. doi: 10.1016/s1074-7613(00)00014-5. Immunity. 2000. PMID: 10933401
The interferons and cell death: guardians of the cell or accomplices of apoptosis?
Barber GN. Barber GN. Semin Cancer Biol. 2000 Apr;10(2):103-11. doi: 10.1006/scbi.2000.0313. Semin Cancer Biol. 2000. PMID: 10936061 Review.
Vesicular stomatitis virus (VSV) therapy of tumors.
Balachandran S, Barber GN. Balachandran S, et al. Among authors: barber gn. IUBMB Life. 2000 Aug;50(2):135-8. doi: 10.1080/713803696. IUBMB Life. 2000. PMID: 11185959
Analyzing the mechanisms of interferon-induced apoptosis using CrmA and hepatitis C virus NS5A.
Ezelle HJ, Balachandran S, Sicheri F, Polyak SJ, Barber GN. Ezelle HJ, et al. Among authors: barber gn. Virology. 2001 Mar 1;281(1):124-37. doi: 10.1006/viro.2001.0815. Virology. 2001. PMID: 11222103
Barber. (2000b) J. Virol. 74, 1513-1523). Given these findings, it is thus plausible that rather than specifically target IFN-inducible genes such as PKR, viruses could also subvert the mechanisms of IFN action, in part, at locations that could block the apoptotic cascade.
Barber. (2000b) J. Virol. 74, 1513-1523). Given these findings, it is thus plausible that rather than specifically target IFN-inducib
Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis.
Balachandran S, Porosnicu M, Barber GN. Balachandran S, et al. Among authors: barber gn. J Virol. 2001 Apr;75(7):3474-9. doi: 10.1128/JVI.75.7.3474-3479.2001. J Virol. 2001. PMID: 11238874 Free PMC article.
Barber, IUBMB Life 50:135-138, 2000). In this study, we further demonstrated, in vivo, the efficacy of VSV antitumor action by showing that tumors that are defective in p53 function or transformed with myc or activated ras are also susceptible to viral cytolysis. ...
Barber, IUBMB Life 50:135-138, 2000). In this study, we further demonstrated, in vivo, the efficacy of VSV antitumor action by showin
Host defense, viruses and apoptosis.
Barber GN. Barber GN. Cell Death Differ. 2001 Feb;8(2):113-26. doi: 10.1038/sj.cdd.4400823. Cell Death Differ. 2001. PMID: 11313713 Review.
Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR.
Saunders LR, Perkins DJ, Balachandran S, Michaels R, Ford R, Mayeda A, Barber GN. Saunders LR, et al. Among authors: barber gn. J Biol Chem. 2001 Aug 24;276(34):32300-12. doi: 10.1074/jbc.M104207200. Epub 2001 Jul 3. J Biol Chem. 2001. PMID: 11438536
Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma.
Toomey NL, Deyev VV, Wood C, Boise LH, Scott D, Liu LH, Cabral L, Podack ER, Barber GN, Harrington WJ Jr. Toomey NL, et al. Among authors: barber gn. Oncogene. 2001 Oct 25;20(48):7029-40. doi: 10.1038/sj.onc.1204895. Oncogene. 2001. PMID: 11704827
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